Alexander M Herman, Longwen Huang ... Benjamin R Arenkiel
Optogenetic techniques, whereby light is used to activate neuronal cells, are quickly becoming widely used in neuroscience; but excessive exposure to light can actually silence certain types of neuronal cells.
PTBP2 ensures that adult protein variants are expressed only in mature neurons through regulation of alternative splicing during early neuronal development.
Daine R Lesniak, Kara L Marshall ... Ellen A Lumpkin
Computer simulations show that the firing patterns of branched touch receptors can be set in part by the organization of their sensory endings in the skin.
Rishidev Chaudhuri, Alberto Bernacchia, Xiao-Jing Wang
Specific types of heterogeneity in the connectivity profile of a biological network give rise to dynamics with a hierarchy of localized temporal scales.
Sabrina Asteriti, Claudia Gargini, Lorenzo Cangiano
Electrophysiological recordings show that cones in the eyes of mice are able to receive strong input from rods via gap junctions, supporting the view that this route plays an important role in vision.
During learning, one climbing fiber input instructs plasticity that is expressed in the simple-spike responses of cerebellar Purkinje cells, and causes neural learning that may inhibit future climbing fiber instructions.
Ana I Domingos, Aylesse Sordillo ... Jeffrey M Friedman
Natural sugars are preferred over artificial sweeteners because of their nutritional content, which is sensed by MCH neurons in the lateral hypothalamus.
