Neuroscience

Neuroscience

eLife publishes research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    Neuropsychological evidence of multi-domain network hubs in the human thalamus

    Kai Hwang et al.
    Lesions to the anterior-medio-dorsal thalamus cause widespread behavioral impairments across multiple cognitive domains, suggesting that thalamic hubs are critical for interconnecting diverse cognitive processes.
    1. Neuroscience

    Experience-dependent weakening of callosal synaptic connections in the absence of postsynaptic FMRP

    Zhe Zhang et al.
    Postnatal, postsynaptic loss of FMRP specifically weakens callosal synaptic inputs onto L2/3 pyramidal neurons, in requirement ofnormal sensory experience, through downregulating AMPA receptor transmission and without affecting local synaptic inputs during cortical circuit development.
    1. Genetics and Genomics
    2. Neuroscience

    The structure of behavioral variation within a genotype

    Zachary Werkhoven et al.
    Multidimensional analysis of data from high-throughput behavioral assays reveals many independent axes of behavioral variation among inbred animals reared in the same environment.
    1. Neuroscience

    Dynamic dichotomy of accumbal population activity underlies cocaine sensitization

    Ruud van Zessen et al.
    Cocaine elicits opposing activity changes in D1R vs D2R spiny projection neurons of the nucleus accumbens with much variability, subsequent recruitment of a subset of D1R neurons drives behavioral sensitization.
    1. Neuroscience

    Early life experience sets hard limits on motor learning as evidenced from artificial arm use

    Roni O Maimon-Mor et al.
    Biological- or artificial-arm experience during early development has a significant effect on artificial-arm motor control in adulthood, providing evidence for limited sensorimotor plasticity beyond childhood.

Highlights

    1. Neuroscience

    Decoding the infrastructure of the cerebellum

    Willem S van Hoogstraten, Chris I De Zeeuw
    1. Evolutionary Biology
    2. Neuroscience

    On the origin of fly species

    Hui Gong, Lucia Prieto-Godino

Senior editors

  1. Michael J Frank
    Brown University, United States
  2. John Huguenard
    Stanford University School of Medicine, United States
  3. Tamar Makin
    University College London, United Kingdom
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