Neuroscience

Latest articles

1. 1. Neuroscience

   Data-driven reduction of dendritic morphologies with preserved dendro-somatic responses

   Willem AM Wybo et al.

   A flexible and accurate methodology to fit reduced compartmental models to dendritic morphologies shows that models with very few compartments can capture many dendritic computations.
2. 1. Neuroscience

   Release probability increases towards distal dendrites boosting high-frequency signal transfer in the rodent hippocampus

   Dmitri A Rusakov et al.

   Excitatory synapses that occur further away from the postsynaptic cell soma exhibit greater neurotransmitter release probability, which appears to improve signal transfer fidelity for high-frequency afferent firing.
3. 1. Neuroscience

   A cell atlas of the chick retina based on single-cell transcriptomics

   Masahito Yamagata et al.

   A molecular atlas of the chick retina provides a comprehensive classification and characterization of 136 cell types, yielding novel insights into retinal structure, function, development, and evolution.
4. 1. Genetics and Genomics
   2. Neuroscience

   Roles of the ClC chloride channel CLH-1 in food-associated salt chemotaxis behavior of C. elegans

   Chanhyun Park et al.

   A ClC chloride channel protein allows neurons to interpret both temporal resolution and intensity of sensory input, which thereby contributes to an experience-dependent navigation behavior.
5. 1. Neuroscience

   Subcellular sequencing of single neurons reveals the dendritic transcriptome of GABAergic interneurons

   Julio D Perez et al.

   Single somata and dendrites of individual rat neurons were laser-captured and sequenced to discover and compare the subcellular transcriptomes, identifying over 4000 mRNAs in GABAergic dendrites.
6. 1. Neuroscience

   Activation of MAP3K DLK and LZK in Purkinje cells causes rapid and slow degeneration depending on signaling strength

   Yunbo Li et al.
7. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

   Laura J Wagstaff et al.

   In vivo experiments on transgenic mice, and cell culture studies, establish Schwann cell c-Jun as a central regulator of peripheral nerve repair, and repair failure, during aging and chronic denervation.
8. 1. Neuroscience

   Layer 6 ensembles can selectively regulate the behavioral impact and layer-specific representation of sensory deviants

   Jakob Voigts et al.

   Changing which layer 6 neurons are active during sensory tasks disrupts the detection and encoding of changes, but still allows integration of sensory information in the absence of changes.
9. 1. Developmental Biology
   2. Neuroscience

   Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes

   Maria Schörnig et al.
10. 1. Neuroscience

    Human complex exploration strategies are enriched by noradrenaline-modulated heuristics

    Magda Dubois et al.

    Humans supplement complex, resource-demanding strategies with simple heuristics for solving the exploration-exploitation dilemma, and noradrenaline functioning controls their utilisation.