Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles

    Brian D Mueller, Sean A Merrill ... Erik M Jorgensen
    The Caenorbhaditis elegans presynapse contains two pools of synaptic vesicles at the active zone, coupled to either neuronal-type or muscle-type calcium channels, and to different docking machinery.
    1. Cell Biology
    2. Neuroscience

    Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell

    Yu Wang, Meghan Lee Arnold ... Barth D Grant
    Giant neuron derived vesicles called exophers are processed by phagocytosis in neighboring skin cells, and the phagocytic interaction promotes exopher production.
    1. Neuroscience

    Netrin-1 regulates the balance of synaptic glutamate signaling in the adult ventral tegmental area

    Marcella M Cline, Barbara Juarez ... Larry S Zweifel
    Genetic analysis of Ntn1 in adult mouse midbrain neurons reveals its function in maintaining excitatory synapses, loss of Ntn1 function in inhibitory neurons is significantly detrimental to mesolimbic system function.
    1. Neuroscience

    A parabrachial to hypothalamic pathway mediates defensive behavior

    Fan Wang, Yuge Chen ... Zhihua Gao
    Neural circuit research reveals a previously unrecognized role for the LPBCCK-PVN pathway in controlling defensive behaviors.
    1. Computational and Systems Biology
    2. Neuroscience

    Asymmetric retinal direction tuning predicts optokinetic eye movements across stimulus conditions

    Scott C Harris, Felice A Dunn
    Retinal physiology and anatomy and visual behavior reveal how sensory circuits in the retina can shape an organism’s eye movements over a range of ethologically relevant stimulus conditions.
    1. Neuroscience

    The entorhinal-DG/CA3 pathway in the medial temporal lobe retains visual working memory of a simple surface feature

    Weizhen Xie, Marcus Cappiello ... Weiwei Zhang
    High-resolution fMRI data reveal an often-neglected contribution of the medial temporal lobe circuitry to item-specific representation in visual working memory, suggesting the mechanism traditionally deemed dedicated to long-term memory can be exploited to support the quality of human working memory.
    1. Neuroscience

    Neural learning rules for generating flexible predictions and computing the successor representation

    Ching Fang, Dmitriy Aronov ... Emily L Mackevicius
    A recurrent network using a simple, biologically plausible learning rule can learn the successor representation, suggesting that long-horizon predictions are computations that are easily accessible in neural circuits.
    1. Neuroscience

    Rapid learning of predictive maps with STDP and theta phase precession

    Tom M George, William de Cothi ... Caswell Barry
    A close approximation to the successor representation is learnt by a simple spike-time-dependent learning rule between cells undergoing theta phase precession.

Senior editors

  1. Timothy Behrens
    University of Oxford, United Kingdom
  2. Tirin Moore
    Howard Hughes Medical Institute, Stanford University, United States
  3. Ma-Li Wong
    State University of New York Upstate Medical University, United States
  4. See more editors