Stem Cells and Regenerative Medicine

Latest articles

1. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states

   Junjun Yao, Shaoxing Dai ... Tianqing Li

   A single-nucleus transcriptomic atlas reveals the molecular signatures and trajectory dynamics of the neurogenic lineage in the human hippocampus during neonatal development, adulthood, aging, and after injury.
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Tuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells

   Léa Torcq, Sara Majello ... Anne A. Schmidt
3. 1. Stem Cells and Regenerative Medicine

   Disease modeling and pharmacological rescue of autosomal dominant Retinitis Pigmentosa associated with RHO copy number variation

   Sangeetha Kandoi, Cassandra Martinez ... Deepak A. Lamba
4. 1. Stem Cells and Regenerative Medicine

   Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells

   Fanny-Meï Cloarec-Ung, Jamie Beaulieu ... David JHF Knapp
5. 1. Stem Cells and Regenerative Medicine

   A versatile high-throughput assay based on 3D ring-shaped cardiac tissues generated from human induced pluripotent stem cell-derived cardiomyocytes

   Magali Seguret, Patricia Davidson ... Jean-Sébastien Hulot

   A novel hydrogel-based platform uses a limited number of cells for tissue generation and offers unique advantages for high-throughput cardiac tissue culture.
6. 1. Stem Cells and Regenerative Medicine

   Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis

   Shintaro Watanuki, Hiroshi Kobayashi ... Keiyo Takubo

   Isotope tracing, mathematical modeling, and single-cell ATP analysis reveal changes in blood cell metabolism under various conditions, showing stressed hematopoietic stem cells support hematopoiesis through glycolytic ATP production via PFKFB3.
7. 1. Stem Cells and Regenerative Medicine

   Endocrine disruptor-induced epimutagenesis in vitro: Insight into molecular mechanisms

   Jake D. Lehle, Yu-Huey Lin ... John R. McCarrey
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish

   Laura Massoz, David Bergemann ... Isabelle Manfroid
9. 1. Stem Cells and Regenerative Medicine

   Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway

   Ryosuke Isotani, Masaki Igarashi ... Toshimasa Yamauchi
10. 1. Stem Cells and Regenerative Medicine

    Switching of RNA splicing regulators in immature neuroblasts: a key step in adult neurogenesis

    Corentin Bernou, Marc-André Mouthon ... François D. Boussin