Highlights

  • Mapping regulatory DNA

    Cis-regulatory elements in the large genome of Parhyale hawaiensis can be identified by integrating chromatin accessibility and sequence conservation data.

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Reviewed Preprint Updated

  • Hypoxia to healthspan

    Genetic tools highlight potential signalling components underlying hypoxia-induced longevity in C. elegans.

    Elizabeth S Kitto, Shijiao Huang ... Scott F Leiser
    Reviewed Preprint Updated

  • Symbionts shape pest traits

    Novel endosymbiotic bacteria have contrasting effects on the performance and dispersal of Russian wheat aphids and on the severity of damage caused to cereal host plants.

    Xinyue Gu, Alex Gill ... Ary A Hoffmann
    Reviewed Preprint

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    State-, Trait- and Recovery-Related Differences in Reinforcement Learning and Value-Based Decision Making in Major Depressive Disorder

    Madeleine Moses-Payne, Ruibin Zhang ... Jonathan Roiser
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Non-invasive measurement of neurotransmitter-specific glucose metabolism in the human brain using proton-observed proton-edited 13C-MRS (POPE13C-MRS)

    Antoine Cherix, Oliver Haermson ... Charlotte Stagg
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Neuroscience

    Dissociation between impaired explicit spatial remapping and preserved implicit neural dynamics in Alzheimer’s disease

    Xueling Wang, Yimeng Wang ... Chenguang Zheng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    foxQ2 marks fast-acting interneurons including dopaminergic neurons of mushroom bodies and central complex in the beetle T. castaneum

    Ying Pang, Bastian Klußmann-Fricke ... Gregor Bucher
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Cognitive control networks in human and macaque

    Valentina Mione, Freja Holm Prins ... John Duncan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Physics of Living Systems

    An engineered multi-step differentiation program in Escherichia coli for self-organized spatial patterning

    Emanuele Boni, Hélène Siboulet ... Yolanda Schaerli
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

    Abhilasha Joshi, Alison E Comrie ... Loren M Frank
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Long-range inhibitory axons from medial entorhinal cortex target lateral entorhinal neurons projecting to the hippocampal formation

    Eirik S Nilssen, Bente Jacobsen ... Menno P Witter
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Heterogeneous responses to embryonic critical period perturbations within the Drosophila larval locomotor circuit

    Niklas Krick, Jacob Davies ... Matthias Landgraf
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Distinct goal location beta frequency dynamics in hippocampus and prefrontal cortex across learning

    Glingna Wang, Nan Zhou ... Jai Y Yu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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Magazine

    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan

  2. Research Culture: From East to West – an early-career researcher’s voyage across continents

    Samuel C Eziuzor
  3. Close-up of an iris

    Episode 105: September 2026

    1. Cell Biology
    2. Computational and Systems Biology

    Philosophy of Biology: The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    1. Genetics and Genomics

    Environmental Learning: How experience shapes individuality

    Bassem A Hassan

  6. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
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  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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