Highlights

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    Eed, a subunit of the enzyme PRC2, controls important processes in craniofacial development after induction of the neural crest.

    Tim Casey-Clyde, S John Liu ... David R Raleigh
    Research Article

  • The power of pyruvate

    The metabolic fate of a nutrient called pyruvate determines how big cells become.

    Ashish G Toshniwal, Geanette Lam ... Jared Rutter
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  • Microglia on the move

    Microglia adopt fundamentally different strategies for surveilling the health of neurons during chronic neurodegeneration.

    Sunitha Subhramanian, Olga Bocharova ... Ilia V Baskakov
    Reviewed Preprint Updated

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    Lysosome-related vacuoles control the metabolism of inorganic polyphosphates to stabilize the concentration of phosphate in the cytosol.

    Samuel Bru, Lydie Michaillat Mayer ... Andreas Mayer
    Research Article

  • Equity, diversity and inclusion

    eLife has published its 10th report on its work to address inequities in research and publishing.

    Inside eLife

  • The SAFE Labs Handbook

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    Erika Donà, James M Gahan ... Philip Coen
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    Continuous developmental changes in word recognition support language learning across early childhood

    Michael C Frank, Virginia A Marchman ... Martin Zettersten
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics
    2. Medicine

    Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach

    Jacky Guy, Elena Hein ... Adrian Bird
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Spatial learning in multi-scale environments: Roles of hippocampus, orbitofrontal cortex, and retrosplenial cortex

    Yidan Qiu, Senning Zheng ... Ruiwang Huang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    The Self-Interest of Adolescents Overrules Cooperation in Social Dilemmas

    Xiaoyan Wu, Hongyu Fu ... Chao Liu
    Revised
    Reviewed Preprint v2
    Updated
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    • Solid
    1. Computational and Systems Biology

    Generative modeling for RNA splicing prediction and design

    Di Wu, Natalie Maus ... Yoseph Barash
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    • Important
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    1. Neuroscience

    A differentiable model for optimizing the genetic drivers of synaptogenesis

    Tommaso Boccato, Matteo Ferrante, Nicola Toschi
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    Reviewed Preprint v1
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    1. Ecology

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    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
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    • Important
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    1. Neuroscience

    Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling

    Stephan Tetenborg, Eyad Shihabeddin ... John O’Brien
    Revised
    Reviewed Preprint v3
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    1. Neuroscience

    The dominance of large-scale phase dynamics in human cortex, from delta to gamma

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    Revised
    Reviewed Preprint v2
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    • Important
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Magazine

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    1. Microbiology and Infectious Disease

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  6. Research Culture: The SAFE Labs Handbook as a tool for improving lab culture

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    Angela Montero, Lydia WS Finley
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