Highlights

We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    Synaptic vesicle undocking induces low frequency depression

    Melissa Silva, Federico F Trigo ... Alain Marty
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Neuroscience

    Esr1-Dependent Signaling and Transcriptional Maturation in the Medial Preoptic Area of the Hypothalamus Shapes the Development of Mating Behavior during Adolescence

    Koichi Hashikawa, Yoshiko Hashikawa ... Garret D Stuber
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Characterisation of cold-selective lamina I spinal projection neurons

    Aimi N Razlan, Wenhui Ma ... Junichi Hachisuka
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine

    Navigating the Path: Making Smart Choices… Advice to Physician Scientists on Choosing a Clinical Specialty

    Talia H Swartz, José E Cavazos ... Christopher S Williams
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Hierarchical cortical plasticity in congenital sight impairment

    Roni O Maimon-Mor, Mahtab Farahbakhsh ... Tessa M Dekker
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Investigating the native functions of [NiFe]-CODH through genomic context analysis

    Maximilian Böhm, Henrik Land
    Genomic neighborhood signatures delineate catalytic versus putative regulatory CODH clades, establishing a framework for predicting enzyme functionality and guiding discovery of biocatalysts for CO2 reduction.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Separating selection from mutation in antibody language models

    Frederick A Matsen IV, Will Dumm ... Hugh K Haddox
    Factoring out nucleotide-level mutation biases from antibody language models dramatically improves prediction of functional mutation effects while reducing computational cost by orders of magnitude.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Detecting directed motion and confinement in single-particle trajectories using hidden variables

    François Simon, Guillaume Ramadier ... Lucien E Weiss
    Exatrack is a framework for analyzing Brownian, directed, and confined motion using a hidden-variable probabilistic model to extract physical insight into particle diffusion.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

    Yuzhen Liu, Christopher D McGann ... Devin K Schweppe
    DNA O-MAP enables proximity labeling at specific genomic loci in fixed cells using programmable oligonucleotides, revealing locus-proximal proteomes and chromatin interactions without genetic modification.
    1. Neuroscience

    A behavioral architecture for realistic simulations of Drosophila larva locomotion and foraging

    Panagiotis Sakagiannis, Anna-Maria Jürgensen, Martin Paul Nawrot
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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Magazine

    1. Neuroscience

    Memory Encoding and Retrieval: Rethinking how memories are retrieved

    Rocco Pizzarelli, Marilena Griguoli
    1. Structural Biology and Molecular Biophysics

    Membrane Biology: Two binding sites are better than one

    Mackenzie K Scott, John E Burke
    1. Neuroscience

    Psychedelic Drugs: Reshaping human neurons

    Jessica L Maltman, Javier González-Maeso
    1. Structural Biology and Molecular Biophysics

    Membrane Proteins: A missing link for efflux pumps

    Hilal Wehbi, Isabelle Broutin
    1. Microbiology and Infectious Disease

    Gut Microbiome: Bacteria weigh up costs and benefits of mobile weapons

    Zhao Wang, Yang Fu

  6. Point of View: An easy way to improve lab meetings

    Cara Glynn, Tiago Monteiro
    1. Neuroscience

    Neuropathic Pain: Closing in on the causes of chronic neuropathic pain

    Geoffroy Laumet
  8. See more Magazine articles

Categories

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  4. Chromosomes and Gene Expression
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  9. Evolutionary Biology
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  11. Immunology and Inflammation
  12. Medicine
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