Highlights

Latest research

    1. Structural Biology and Molecular Biophysics

    A structural code for assembly specificity in GID/CTLH-type E3 ligases

    Pia Maria van gen Hassend, Hermann Schindelin
    Structural characterization of the CTLH-CRA domain-mediated pairing in the CTLH ubiquitin ligase complex enables rational engineering of interfaces with altered binding specificity.
    1. Ecology
    2. Evolutionary Biology

    Fitness drivers of division of labor in vertebrates

    Irene García-Ruiz, Dustin R Rubenstein
    Direct survival benefits in larger groups rather than kin-selected indirect fitness primarily drive the evolution of division of labor in cooperatively breeding vertebrates, particularly under harsh environmental conditions.
    1. Cell Biology

    Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions

    Sunayana Sarkar, Harsha Sharma ... Manish Jaiswal
    A genetic toolkit establishes Drosophila as a tractable metazoan system for systematic interrogation of conserved biological functions of the ancient polymer polyphosphate.
    1. Neuroscience

    A multi-resolution imaging and analysis pipeline for comparative circuit reconstruction in insects

    Valentin Gillet, Marcel E Sayre ... Stanley Heinze
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cancer Biology

    JAK-STAT Pathway Heterogeneity Governs Immunotherapy Response in Breast Cancer

    Jianbo Zhou, Heng Zhang ... Fu Peng
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Immunology and Inflammation

    Integrated single cell multiomic profiling and functional validation reveal distinct cellular routes to human plasma cell differentiation

    Colin A Fields, James F Read ... Deepta Bhattacharya
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Mood computational mechanisms underlying increased risk behavior in adolescent suicidal patients

    Zhihao Wang, Tian Nan ... Bastien Blain
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Synaptic vesicle undocking induces low frequency depression

    Melissa Silva, Federico F Trigo ... Alain Marty
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Neuroscience

    Two neuropeptides that promote blood feeding in Anopheles stephensi mosquitoes

    Prashali Bansal, Roshni Pillai ... Sonia Q Sen
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid