Highlights

  • No change for astroctyes

    Genetically removing the RNA-binding protein PTBP1 from astrocytes does not convert them into neurons, contrary to previous claims.

    Min Zhang, Naoto Kubota ... Sika Zheng
    Research Article
  • Eed and craniofacial development

    Eed, a subunit of the enzyme PRC2, controls important processes in craniofacial development after induction of the neural crest.

    Tim Casey-Clyde, S John Liu ... David R Raleigh
    Research Article
  • Phosphate buffering

    Lysosome-related vacuoles control the metabolism of inorganic polyphosphates to stabilize the concentration of phosphate in the cytosol.

    Samuel Bru, Lydie Michaillat Mayer ... Andreas Mayer
    Research Article
  • How we understand each other

    eLife author Joe Barnby answers questions about a study that explored how humans navigate social interactions.

    Inside eLife
  • Focus Issue: Trained Immunity

    The articles in this focus issue discuss progress towards a better understanding of memory in the innate immune system, and efforts to develop new vaccines and therapeutics based on “trained immunity”.

    Collection
  • Equity, diversity and inclusion

    eLife has published its 10th report on its work to address inequities in research and publishing.

    Inside eLife

Latest research

    1. Neuroscience

    Characterisation of cold-selective lamina I spinal projection neurons

    Aimi N Razlan, Wenhui Ma ... Junichi Hachisuka
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity

    Sen-Lin Lai, Chris Q Doe
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    The basolateral amygdala complex and perirhinal cortex represent focal and peripheral states of information processing in rats

    Francesca S Wong, A Simon Killcross ... Nathan M Holmes
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in Mycobacterium intracellulare

    Yoshitaka Tateishi, Yuriko Ozeki ... Sohkichi Matsumoto
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Convincing
    1. Ecology

    Cardenolide toxin diversity impacts monarch butterfly growth and sequestration

    Anurag A Agrawal, Amy P Hastings, Paola Rubiano-Buitrago
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Continuous flashing suppression of V1 responses and the perceptual consequences revealed via two-photon calcium imaging and transformer modeling

    Cai-Xia Chen, Xin Wang ... Cong Yu
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    EEG decodability of facial expressions and their stereoscopic depth cues in immersive virtual reality

    Felix Klotzsche, Ammara Nasim ... Michael Gaebler
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    DANCE: An open-source analysis pipeline and low-cost hardware to quantify aggression and courtship in Drosophila

    R Sai Prathap Yadav, Paulami Dey ... Pavan Agrawal
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Modulating task outcome value to mitigate real-world procrastination via noninvasive brain stimulation

    Zhiyi Chen, Zhilin Ren ... Tingyong Feng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Persistent contacts between Climp63 and microtubules cause mitotic defects and nuclear fragmentation

    Jelmi uit de Bos, Ulrike Kutay
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing