Highlights

We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Medicine
    2. Immunology and Inflammation

    PDL-1+ Neutrophils mediate susceptibility during endotoxemia in Metabolically Dysfunctional-Associated Fatty Liver Disease

    Cleyson da Cruz Oliveira Barros, Alexandre Kanashiro ... Fernando Queiroz Cunha
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Real-Time Closed-Loop Feedback System For Mouse Mesoscale Cortical Signal And Movement Control: CLoPy

    Pankaj K Gupta, Timothy H Murphy
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Humans underestimate their body mass in microgravity: evidence from reaching movements during spaceflight

    Zhaoran Zhang, Yu Tian ... Kunlin Wei
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Cell Biology

    Secreted exosomes induce filopodia formation

    Caitlin McAtee, Mikin R Patel ... Alissa M Weaver
    Exosome-associated THSD7A is identified as a key trigger of filopodia formation in cancer cells and neurons, revealing a novel pathway with implications for metastasis, neuronal connectivity, and other filopodia-dependent processes.
    1. Computational and Systems Biology

    Nonlinear transcriptional responses to gradual modulation of transcription factor dosage

    Júlia Domingo, Mariia Minaeva ... Tuuli Lappalainen
    A new CRISPR-based approach for tuning gene expression up and down allowed identification of how other genes' expression responds to changes of transcription factors.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response

    Long-Feng Lu, Can Zhang ... Shun Li
    CDK2-mediated TBK1 degradation via Dtx4 represents a previously unrecognized regulatory mechanism that modulates antiviral immunity in fish.
    1. Developmental Biology
    2. Neuroscience

    Afadin sorts different retinal neuron types into accurate cellular layers

    Matthew R Lum, Sachin Patel ... Xin Duan
    Genetic perturbation of Afadin in the retina reveals its importance for the precise organization of the retinal layers while leaving neuronal fate and numbers unaffected.
    Version of Record
    Short Report
    • Important
    • Solid
    1. Neuroscience

    A unifying account of replay as context-driven memory reactivation

    Zhenglong Zhou, Michael J Kahana, Anna C Schapiro
    A context-driven memory model simulates a wide range of characteristics of waking and sleeping hippocampal replay, providing a new account of how and why replay occurs.
    1. Developmental Biology
    2. Computational and Systems Biology

    A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales

    Alice Gros, Jules Vanaret ... Sham Tlili
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Medicine
    2. Neuroscience

    Impaired Adaptive Learning in Chronic Pain Contributes to Apathy

    Xinyuan Yan, Crina M Peterson ... David P Darrow
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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Magazine

    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Chromosomes: Finding a role for non-coding DNA in trypanosomes

    Markus R Schmidt
    1. Cancer Biology
    2. Cell Biology

    Chemotherapy: Lipid balance and chemoresistance in cancer cells

    Kaori Kanemaru, Yoshikazu Nakamura
    1. Genetics and Genomics
    2. Physics of Living Systems

    Raman Spectroscopy: Probing the proteome

    Wei-Hsiang Lin, Chia-Liang Cheng
    1. Genetics and Genomics
    2. Neuroscience

    Opioid Use Disorder: Identifying new targets in the fight against opioids

    Fernanda Laezza
    1. Cancer Biology

    Breast Cancer: Slowing the growth of drug-resistant tumors

    Yingyi Zhang, Qianying Lu
    1. Neuroscience

    Experience-Dependent Plasticity: The little brain supervises learning in the big brain

    Martha Garcia, Mark Wagner
    1. Microbiology and Infectious Disease

    Tuberculosis: A surprising new hiding place for a dangerous pathogen

    Sheetal Gandotra, Yogendra Singh
  8. See more Magazine articles

Categories

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  4. Chromosomes and Gene Expression
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  12. Medicine
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  14. Neuroscience
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