Highlights

  • The evolution of effectors

    Pathogens that cause abnormal growths called galls in plants rely on effector molecules with structures and targeting strategies that are conserved across evolutionary lineages.

    Soham Mukhopadhyay, Muhammad Asim Javed ... Edel Perez-Lopez
    Tools and Resources
  • Modelling archaeal membranes

    Archaea use single-headed and double-headed lipids to construct cell membranes that are both flexible and capable of withstanding extreme environments.

    Miguel Amaral, Felix Frey ... Anđela Šarić
    Research Article
  • No change for astroctyes

    Genetically removing the RNA-binding protein PTBP1 from astrocytes does not convert them into neurons, contrary to previous claims.

    Min Zhang, Naoto Kubota ... Sika Zheng
    Reviewed Preprint Updated
  • Genetic pathways in brown algae

    Life-cycle-related patterns of gene expression are conserved across the brown algae.

    Pélagie Ratchinski, Olivier Godfroy ... J Mark Cock
    Reviewed Preprint Updated
  • Tracing cell fates in embryos

    Differences in the activity of an enzyme called CARM1 influence whether blastomeres become part of the embryo or the placenta.

    Ying Zhang, Qi Chen
    Insight
  • New university partnerships

    eLife is partnering with two leading UK universities on open access agreements that promote a more open and equitable approach to scientific publishing.

    Press Pack

Latest research

    1. Cell Biology

    Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

    Devon E Mason, Paula Camacho ... Joel D Boerckel
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Currentscape analysis of dendritic inputs during place field dynamics

    Bence Fogel, Balázs B Ujfalussy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    The time course of visuo-semantic representations in the human brain is captured by combining vision and language models

    Boyan Rong, Alessandro Thomas Gifford ... Radoslaw Martin Cichy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization

    Roland Philipp, Yuki Hara ... Kazuhiko Seki
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Epidemiology and Global Health

    Spatiotemporal relationships between extreme weather events and arbovirus transmission across Brazil

    Victoria M Cox, Felipe Campos de Melo Iani ... Ilaria Dorigatti
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Identifying regulators of associative learning using a protein-labelling approach in C. elegans

    Aelon Rahmani, Anna McMillen ... Yee Lian Chew
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cancer Biology

    Multi-gradient Permutation Survival Analysis Identifies Mitosis and Immune Signatures Steadily Associated with Cancer Patient Prognosis

    Xinlei Cai, Yi Ye ... Hongbin Ji
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Developmental Biology

    Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye

    Alicia Hurtado, Victor López-Soriano ... Francisco Javier Barrionuevo
    The Sox9 gene is necessary for maintaining vision in the mouse adult eye, acting as an essential factor for retinal and corneal function.
    1. Neuroscience

    Mixed evidence for the rhythmicity of auditory perceptual judgements in humans

    Cécile Fabio, Christoph Kayser
    Across multiple experiments, the evidence for any rhythmicity of auditory perception remains difficult to establish.
    1. Evolutionary Biology

    Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (Ooceraea biroi)

    Kip D Lacy, Jina Lee ... Daniel JC Kronauer
    A complementary sex determination locus is conserved in ants and dates back to approximately 112 million years ago.