Highlights

  • Body size and urban survival

    A global study of 30,000 species reveals how body size affects whether wildlife thrives or struggles in cities.

    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
    Research Article
  • Pikas power yak pastures

    Plateau pikas play a role in enhancing weight gains in yaks, by suppressing toxic plants and improving the availability and quality of palatable forage.

    Zhiwei Zhong, Bingbo Ni ... Zhibin Zhang
    Reviewed Preprint Updated
  • Re-evolving traits

    Hybridization chain reaction and confocal imaging reveal latent ocelli gene regulatory network expression in ant workers, with a role in partial re-evolution of caste-specific traits.

    Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
    Research Article
  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial
  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife
  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article

Latest research

    1. Structural Biology and Molecular Biophysics

    In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles

    Zahra Seraj, Ximena Zottig ... Andrei A Korostelev
    Cryogenic electron microscopy of cellular extracts can visualize atomic details and discover new interactions between biological molecules, such as the interactions of the ribosome, the protein-making machinery, with essential proteins to regulate cellular functions.
    1. Neuroscience

    Sensitivity of the human temporal voice areas to nonhuman primate vocalizations

    Leonardo Ceravolo, Coralie Debracque ... Didier Grandjean
    Vocalizations of nonhuman primates, especially when acoustic and phylogenetic proximity is the highest, enhance human brain activity in the anterior temporal lobe.
    1. Neuroscience

    Frequency and laminar profile of feature-specific visual activity revealed by interleaved EEG–fMRI

    Tommy Clausner, José P Marques ... Mathilde Bonnefond
    Combined human laminar EEG–fMRI reveals feature-specific gamma band activity, and dissociates general (lower frequency) from feature-specific (higher frequency) alpha band activity related to superficial and deep cortical layers.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Nutrient Microenvironments Reprogram Pigment Epithelium Metabolism and Phenotype

    Rayne R Lim, Emily Zhao ... Jennifer R Chao
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Chromosomes and Gene Expression

    Volatile diacetyl triggers rapid fmo-2 expression through DHAP-glycerol shunt induction

    Marco Giorda, Anamitra Sen, Martin S Denzel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Mapping abstraction and metacognition onto distinct transdiagnostic symptom profiles

    Taiki Oka, Yoshihiko Kunisato ... Aurelio Cortese
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Immunology and Inflammation

    CD56dimCD16dim NK cells are the dominant effector cells against HIV-infected primary T-cells

    William Howell, Courtney Branch ... Edward Barker
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Bacterial and viral gut microbiome alterations characterize microbiome-immune-pathophysiology axes in sickle cell disease

    Zachary N Flamholz, Jennifer De Los Santos ... Libusha Kelly
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    A high-throughput assay for the measurement of Ca2+-oscillations and insulin release from uniformly sized β-cell spheroids

    Stijn Robben, Patricia Davidson ... Thomas Voets
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Bifunctional Architecture Enables Substrate Catalysis and Channeling in Paracoccus TMAO Demethylase

    Trung Thach, KanagaVijayan Dhanabalan ... Ramaswamy Subramanian
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Incomplete