Highlights

  • Morphogenesis in fungi

    Glycolysis orchestrates morphogenesis and virulence in fungi by regulating the de novo biosynthesis of sulfur-containing amino acids.

    Dhrumi Shah, Nikita Rewatkar ... Sriram Varahan
    Research Article

  • Metal transport breakthrough

    Researchers have identified the transport protein used by the parasite Toxoplasma gondii to import iron and zinc.

    Dana Aghabi, Cecilia Gallego Rubio ... Clare R Harding
    Research Article

  • Social tolerance in macaques

    Species of macaques with high social tolerance have larger amygdalae than species with low social tolerance. Image credit: Sarah Silvère.

    Sarah Silvere, Julien Lamy ... Sebastien Ballesta
    Research Article

  • Research culture

    The Researcher Development Concordat has led to improvements in research culture in the UK, but there is still more to do.

    Robert AR Drake, Laura A Gray ... Joan Chang
    Feature Article

  • Written out of history

    Four women whose pioneering contributions to science have been largely overlooked.

    Lisa M Thomann, Julie Batut
    Feature Article

  • What is a Reviewed Preprint?

    Reviewed Preprints provide benefits to authors and to the wider scientific community.

    Inside eLife
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Cell Biology

    Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis

    Changle Zhao, Yongxun Chen ... Jing Wei
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Designing optimal perturbation inputs for system identification in neuroscience

    Mikito Ogino, Daiki Sekizawa ... Masafumi Oizumi
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Evolutionary Biology

    Inference of germinal center evolutionary dynamics via simulation-based deep learning

    Duncan K Ralph, Athanasios G Bakis ... Frederick A Matsen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Automated genome mining predicts structural diversity and taxonomic distribution of peptide metallophores across bacteria

    Zachary L Reitz, Bita Pourmohsenin ... Marnix Medema
    Automated detection of metallophore biosynthesis reveals that metal-chelating non-ribosomal peptides are widespread, chemically diverse, and deeply rooted in bacterial evolution.
    1. Neuroscience

    Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced mechanical pain hypersensitivity

    Riku Kawanabe-Kobayashi, Sawako Uchiyama ... Makoto Tsuda
    Stress activates a locus coeruleus–spinal dorsal horn noradrenergic circuit that drives mechanical pain hypersensitivity through Hes5-positive astrocytes.
    1. Developmental Biology
    2. Genetics and Genomics

    Drosophila melanogaster model of RVCL-S demonstrates age dependent disease progression

    Elena Gracheva, Abigail Matt ... Chao Zhou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Anesthesia Lowers Spatial Frequency Preference in the Primary Visual Cortex

    Jiahao Wu, Taisuke Yoneda ... Yumiko Yoshimura
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Should I stay or should I go? Spatiotemporal dynamics of bacterial biofilms in confined flows

    Massinissa Benbelkacem, Gabriel Ramos ... Yohan Davit
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics
    2. Evolutionary Biology

    Faroese Whole Genomes Provide Insight into Ancestry and Recent Selection

    Iman Hamid, Ólavur Mortensen ... Noomi O Gregersen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Microbiology and Infectious Disease

    Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation

    Simone Margaard Offersen, Signe Adamberg ... Anders Brunse
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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Magazine

    1. Neuroscience

    Non-Visual Light Perception: Ancient photoreceptor shapes behavioural responses

    N Sören Häfker
    1. Ecology

    Insect Migration: A sense of direction

    Aleksandr Pakhomov, Dmitry Kishkinev
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Virus Evolution: Scaling up efforts to target evolving viruses

    Lin Wang, Henrik Salje
    1. Developmental Biology

    Oocyte Development: The discovery of the mammalian fusome

    Michael Buszczak, Anirban Dasgupta
    1. Neuroscience

    Temporal Information: Synaptic footprints of time in working memory

    Dhruv Grover, Marissa L Heintschel
    1. Developmental Biology
    2. Genetics and Genomics

    Equity, Diversity and Inclusion: Four women whose pioneering contributions to science have been largely overlooked

    Lisa M Thomann, Julie Batut
    1. Neuroscience

    Brain Mapping: Redefining borders in the sensorimotor cortex

    Sylvain Crochet
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
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  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
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  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
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  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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