Highlights

We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Microbiology and Infectious Disease
    2. Evolutionary Biology

    Host and antibiotic jointly select for greater virulence in Staphylococcus aureus

    Michelle Su, Kim L Hoang ... Timothy D Read
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Cancer Biology

    Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8

    Hyunkyung Kong, Jiyeon Choi ... Kevin M Brown
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology

    A single-cell transcriptomic atlas of inner ear morphogenesis in zebrafish

    Akankshi Munjal, Kalki Kukreja ... Ian A Swinburne
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Cancer Biology
    2. Cell Biology

    HER2-driven mammary tumorigenesis enhances bioenergetics despite reductions in mitochondrial content

    Sara M Frangos, Henver S Brunetta ... Graham P Holloway
    Multi-omic and bioenergetic profiling in a HER2-driven mouse model of mammary cancer reveals that reduced mitochondrial content does not limit tumor respiratory capacity, which is instead dramatically elevated compared to benign mammary tissue.
    1. Neuroscience

    Canonical neurodevelopmental trajectories of structural and functional manifolds

    Alicja Monaghan, Richard AI Bethlehem ... Duncan E Astle
    Contrary to prior work, principal axes of structural and functional connectivity are established early in life, remaining stable and undergoing refinement throughout development.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Natural xanthones as α-Mangostin induce vasorelaxation involving key gating residues in the S6 domain of BK channels

    Soenke Cordeiro, Robert Patejdl ... Marianne A Musinszki
    Identification of mangostins as potent BK channel activators links natural xanthones to vascular smooth muscle relaxation, providing a mechanistic basis for their reported antihypertensive effects.
    1. Neuroscience

    Continuous flash suppression of neural responses and population orientation coding in macaque V1

    Cai-Xia Chen, Xin Wang ... Cong Yu
    Continuous flash suppression reduces V1 orientation responses in an ocular-dominance-dependent manner, which may still allow low-level coarse orientation discrimination but provide insufficient information for higher-level visual and cognitive tasks.
    1. Biochemistry and Chemical Biology

    Purified Zymogens Reveal Mechanisms of Snake Venom Metalloproteinase Auto-Activation

    Sophie Hall, Iara Aimê Cardoso ... Christiane Schaffitzel
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Calibrated analysis framework for nanopore direct RNA sequencing uncovers cell-specific m6A stoichiometry at conserved sites

    Denise Ohnezeit, Elene Loliashvili ... Angus C Wilson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Computational and Systems Biology

    Geometry shapes cytoplasmic Cdk1 waves that drive cortical dynamics

    Daniel Cebrián-Lacasa, Marcin Leda ... Lendert Gelens
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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Magazine

    1. Neuroscience

    Vestibular Hair Cells: Are kinocilia motile?

    Ruth Anne Eatock, Marina Kabirova
    1. Neuroscience

    Neurotransmitters: The sound of neural silence

    Nikki Tjahjono, Yu-Shun Wang, Lin Tian
    1. Neuroscience

    Language Models: Does the brain really know what word is coming next?

    Richard J Antonello
    1. Genetics and Genomics
    2. Medicine

    Point of View: Teaching early-career researchers how to respond to peer reviewers

    Eric Kalkhoven, Manon Kluijtmans
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Antibody Language Models: Taking the biology seriously makes models better

    Antonio Matas-Gil, Andreas Tiffeau-Mayer
    1. Neuroscience

    Neuroanatomy: Hidden folds reveal brain organization

    Jürgen Germann
    1. Neuroscience

    Orbitofrontal Cortex: Cocaine disrupts hidden states in the brain

    Margo Le, Ronald Keiflin
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
  17. Plant Biology
  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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