Highlights

  • Mapping regulatory DNA

    Cis-regulatory elements in the large genome of Parhyale hawaiensis can be identified by integrating chromatin accessibility and sequence conservation data.

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Research Article

  • Hypoxia to healthspan

    Genetic tools highlight potential signalling components underlying hypoxia-induced longevity in C. elegans.

    Elizabeth S Kitto, Shijiao Huang ... Scott F Leiser
    Reviewed Preprint Updated

  • Symbionts shape pest traits

    Novel endosymbiotic bacteria have contrasting effects on the performance and dispersal of Russian wheat aphids and on the severity of damage caused to cereal host plants.

    Xinyue Gu, Alex Gill ... Ary A Hoffmann
    Reviewed Preprint

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Biochemistry and Chemical Biology

    A Sequential Assembly Mechanism for Stable Cdc13 Dimerization on Telomeric DNA

    Po-Wei Chiu, Yu-Ting Lin ... Jing-Jer Lin
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Physics of Living Systems

    Thermodynamic principles of enzymatic regulation in biomolecular condensates from reaction-coupled molecular modeling

    Enrico Lavagna, Francesco Delfino ... Alessandro Barducci
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    From static structures to dynamic landscapes: cryo-EM redefines RNA biology

    Shekhar Jadhav, Spandan Saha ... Marco Marcia
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Electroconvulsive stimulation drives cortical spreading depression dependent immediate early gene expression in mice

    Hugo J Ladret, Leonardo Lupori ... Georg B Keller
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Zapit: Open Source Laser-Scanning Photostimulation For Neuroscience

    Michael Lohse, Oliver M Gauld ... Robert AA Campbell
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Ecology

    Wetness modulates the effects of grazing on net ecosystem productivity in global grasslands

    Yueqiang Wu, Le Qi ... Biao Zhu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Transposons contribute to splice-isoform diversity in the Drosophila brain

    Malak Choucri, Tina Rainey, Christoph D Treiber
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Genome-wide discovery of cis-regulatory elements in a large genome

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Integrating genome-wide maps of chromatin accessibility and sequence conservation provides an accessible low-cost approach for identifying cis-regulatory elements in large genomes, validated in the emerging model Parhyale.
    1. Physiology

    Sex-biased expression of enteroendocrine cell-derived hormones contributes to higher fat storage in Drosophila females

    Puja Biswas, Elizabeth J Rideout
    Sex-specific regulation of enteroendocrine hormones shapes energy storage differently in male and female flies.
    1. Developmental Biology

    Bidirectional redistribution of actomyosin drives epithelial invagination in ascidian siphon tube morphogenesis

    Jinghan Qiao, Pengyu Yu ... Bo Dong
    Bidirectional relocation of actomyosin as a novel mechanism drives invagination in developing organs.
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Magazine

    1. Genetics and Genomics
    2. Developmental Biology
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    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan

  2. Research Culture: From East to West – an early-career researcher’s voyage across continents

    Samuel C Eziuzor
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    Episode 105: September 2026

    1. Cell Biology
    2. Computational and Systems Biology

    Philosophy of Biology: The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    1. Genetics and Genomics

    Environmental Learning: How experience shapes individuality

    Bassem A Hassan

  6. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
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Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
  17. Plant Biology
  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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