Highlights

  • Eed and craniofacial development

    Eed, a subunit of the enzyme PRC2, controls important processes in craniofacial development after induction of the neural crest.

    Tim Casey-Clyde, S John Liu ... David R Raleigh
    Research Article
  • The power of pyruvate

    The metabolic fate of a nutrient called pyruvate determines how big cells become.

    Ashish G Toshniwal, Geanette Lam ... Jared Rutter
    Research Article
  • Microglia on the move

    Microglia adopt fundamentally different strategies for surveilling the health of neurons during chronic neurodegeneration.

    Sunitha Subhramanian, Olga Bocharova ... Ilia V Baskakov
    Reviewed Preprint Updated
  • Phosphate buffering

    Lysosome-related vacuoles control the metabolism of inorganic polyphosphates to stabilize the concentration of phosphate in the cytosol.

    Samuel Bru, Lydie Michaillat Mayer ... Andreas Mayer
    Research Article
  • Equity, diversity and inclusion

    eLife has published its 10th report on its work to address inequities in research and publishing.

    Inside eLife
  • The SAFE Labs Handbook

    New handbook could help group leaders to improve research culture in their labs.

    Erika Donà, James M Gahan ... Philip Coen
    Feature Article

Latest research

    1. Neuroscience

    Emergence of Functional Heart-Brain Circuits in a Vertebrate

    Luis Hernandez-Nunez, Joana Avrami ... Mark C Fishman
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Decoding Spine Nanostructure in Mental Disorders Reveals a Schizophrenia-Linked Role for Ecrg4

    Yutaro Kashiwagi, Qingrui Liu ... Shigeo Okabe
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activity

    Ryo Masumura, Kyosuke Goda ... Naofumi Uesaka
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    A three-dimensional immunofluorescence atlas of the brain of the hackled-orb weaver spider, Uloborus diversus

    Gregory Artiushin, Abel Corver, Andrew Gordus
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Individuality transfer: Predicting human decision-making across task conditions

    Hiroshi Higashi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Synergistic MAPT mutations as a platform to uncover modifiers of tau pathogenesis

    Miles R Bryan, Michael F Almeida ... Todd J Cohen
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Solid
    1. Neuroscience

    A Forebrain Hub for Cautious Actions via the Midbrain

    Ji Zhou, Muhammad S Sajid ... Manuel A Castro-Alamancos
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    The representation of facial emotion expands from sensory to prefrontal cortex with development

    Xiaoxu Fan, Abhishek Tripathi, Kelly R Bijanki
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Intersection of transient cell states with stable cell types in hippocampus

    Jack A Olmstead, Lauren E King, Brenda L Bloodgood
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience
    2. Ecology

    New idtracker.ai: rethinking multi-animal tracking as a representation learning problem to increase accuracy and reduce tracking times

    Jordi Torrents, Tiago Costa, Gonzalo G de Polavieja
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling