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Activity fluctuations, or noise correlations, are robust measures of neuronal connectivity and they reveal that neural circuity controls mixing of information at a granular level across millimeter-length scales.

The severity of active tuberculosis in a high-burden population is not explained by host or pathogen genetic variation, suggesting a dominant role for social and environmental factors.

An automated bioluminescent image analysis framework, maRQup, parametrizes tumor dynamics and provides quantitative metrics, enabling large-scale evaluation and optimization of preclinical cancer immunotherapies.

In-cell biophysical analyses identify a sequence-encoded energy storage function of innate immune adaptor proteins that allows cells to respond quickly and decisively to pathogenic signals.

Being responsible for a partner's adverse outcomes is associated with anterior insula activation, while the superior temporal sulcus tracks prediction errors for the partner's reward resulting from the participant's decisions.

A novel pipeline for analyzing longitudinal two-photon microscopy data of cerebrovasculature in mice interrogates the vasculature network before and after optogenetic stimulation, revealing new insights into their coordination.

Stable pressure gradients can arise in cells from the combination of actomyosin-generated cortical tension, cytoplasmic poroelasticity, and water flows across the membrane.

Topographically distributed plCoA populations direct innate olfactory responses by signaling to divergent valence-specific targets, linking upstream olfactory identity to downstream valence behaviors, through a population code.

GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.

Stress-related corticotropin-releasing factor signaling directly modulates striatal cholinergic circuits, and alcohol exposure disrupts this control, revealing a circuit mechanism linking stress, alcohol use, and impaired behavioral flexibility.