Browse our Research Articles

Transcriptomic and metabolite analysis reveal sex differences in circulation and excretion of bile acids in a mouse- model of hepatocellular carcinoma (HCC), and the identified female-specific gene profile correlates with better HCC survival.

ANKEF1 stabilizes the sperm axoneme by reinforcing the nexin–dynein regulatory complex, revealing a mechanical buffering mechanism essential for flagellar integrity and male fertility.

The morphogenesis of brain folding patterns across species is studied by physical gel models, simulations, and a quantitative morphometric analysis.

Maintaining CDK4/6 inhibition constrains drug‑resistant breast tumors by delaying cell‑cycle entry, and adding CDK2 inhibition further deepens control to guide post‑progression therapy.

Post‑HI oxidative‑phosphorylation uncoupling drives secondary energy failure in neonatal brains, and preventing the post‑HI CMRO₂ surge is a key mechanism underlying hypothermia’s neuroprotection.

PLSCR1 is an IFN-λ-stimulated gene that enhances IFN-λR1 expression at both transcriptional and protein level, highlighting the potential for targeting PLSCR1 pathways in anti-influenza therapy.

Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal compass.

Loss of class A scavenger receptor MARCO results in elevated lung Ace expression and elevated plasma aldosterone concentrations in male mice, demonstrating an endocrine function of this immune scavenger receptor.

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

Claims for a Triassic-aged crown lizard merit detailed reanalysis, the results of which find that Cryptovaranoides is not only not a lizard, but is a more distantly related diapsid reptile.