Browse our Research Articles

Page 2 of 1,420
    1. Cancer Biology
    2. Computational and Systems Biology

    Altered thymic niche synergistically drives the massive proliferation of malignant thymocytes

    Erika Tsingos, Advaita M Dick, Baubak Bajoghli
    Combining computer modeling and experiments in animals shows that the spatial organization of thymic epithelial cells affects the availability of signaling molecules that regulate thymocyte proliferation and development.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Magnetotactic bacteria optimally navigate natural pore networks

    Alexander P Petroff, Julia Hernandez ... Nina Radchenko-Hannafin
    Diverse magnetotactic bacteria are adapted to the local geomagnetic field and grain size to maximize their swimming speed through the pore space.
    1. Cell Biology
    2. Evolutionary Biology

    Horizontally transferred cell-free chromatin particles function as autonomous ‘satellite genomes’ and vehicles for transposable elements within host cells

    Soumita Banerjee, Soniya Sanjay Shende ... Indraneel Mittra
    Uptake of cell-free chromatin particles released from dying cells and carrying non-coding DNA could redefine mammalian genomics.
    1. Evolutionary Biology

    The success of artificial selection for collective composition hinges on initial and target values

    Juhee Lee, Wenying Shou, Hye Jin Park
    Mathematical modeling uncovers how initial and target compositions limit microbial community selection, as inter-community selection clashes with intra-community selection like a rafter battling a waterfall.
    1. Structural Biology and Molecular Biophysics

    Crosslinking by ZapD drives the assembly of short FtsZ filaments into toroidal structures in solution

    Adrián Merino-Salomón, Jonathan Scheneider ... German Rivas
    Promoting FtsZ toroidal polymer formation by ZapD offers new insights into stabilizing the bacterial division ring.
    1. Cancer Biology

    SETD2 suppresses tumorigenesis in a KRASG12C-driven lung cancer model, and its catalytic activity is regulated by histone acetylation

    Ricardo J Mack, Natasha M Flores ... Or Gozani
    Genetic and biochemical studies show that SETD2 is tumor suppressive in a lung cancer mouse model and SETD2 methylation activity in vitro is regulated by histone acetylation.
    1. Evolutionary Biology

    The general version of Hamilton’s rule

    Matthijs van Veelen
    The flexibility of the general version of Hamilton's rule allows the rule to match the complexity of the model of social behaviour, or the complexity implied by the data.
    1. Microbiology and Infectious Disease

    Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils

    Marietta M Ravesloot-Chavez, Erik Van Dis ... Sarah A Stanley
    Wild-derived mice exhibit diversity in outcomes after infection with Mycobacterium tuberculosis.
    1. Neuroscience

    Sequence action representations contextualize during early skill learning

    Debadatta Dash, Fumiaki Iwane ... Leonardo G Cohen
    When learning a new skill, neural representations of individual actions rapidly incorporate contextual information pertaining to the encompassing skill sequence-primarily during rest breaks interleaved with practice.
    1. Neuroscience

    The spatial frequency representation predicts category coding in the inferior temporal cortex

    Ramin Toosi, Behnam Karami ... Mohammad-Reza A Dehaqani
    Spatial frequency is explicitly and dynamically represented in the primate inferior temporal cortex, revealing distinct neural populations that differentially support object recognition, specially emphasizing high-frequency contributions to face processing.