Browse our Research Articles

Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor immunity.

Superoxide dismutases, particularly Sod1, differentially tune redox signaling of germline and cyst stem cells, enabling their self-renewal and differentiation, thereby maintaining Drosophila testicular stem cell homeostasis.

NAT10-mediated mRNA acetylation links neural activity to local protein synthesis at synapses, influencing memory consolidation.

Chloroquine interferes with artemisinin activation, and such interactions should be considered when formulating antimalarial drug combinations.

GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.

Stable pressure gradients can arise in cells from the combination of actomyosin-generated cortical tension, cytoplasmic poroelasticity, and water flows across the membrane.

Topographically distributed plCoA populations direct innate olfactory responses by signaling to divergent valence-specific targets, linking upstream olfactory identity to downstream valence behaviors, through a population code.

Stress-related corticotropin-releasing factor signaling directly modulates striatal cholinergic circuits, and alcohol exposure disrupts this control, revealing a circuit mechanism linking stress, alcohol use, and impaired behavioral flexibility.

Studying the reproductive life history of an acoel reveals that a body-size-dependent program regulates organ growth and regeneration dynamics and discovers a novel form of egg-laying behavior.

Competition between Quaking and SF1 for a subset of ACUAA intron branch sites influences alternative splicing in different tissues and organisms.