Browse our Research Articles

The direct observation of collagen using magnetic resonance imaging is possible, presenting a new method to study the protein in vivo.

HSD17B7-dependent cholesterol biosynthesis is essential for hair cell function, implicating HSD17B7 disruption in the pathogenesis of hearing loss.

Connexin43 is the most ubiquitously expressed connexin in the human body, and the CO₂-dependent opening of Connexin43 hemichannels implies that CO₂ may influence many physiological processes.

A range of biophysical techniques is used in combination with computational analysis to understand whether glutamine-binding protein binds its ligand via the induced-fit or conformational selection mechanism.

Pericytes regulate cerebrovascular development, while vascular smooth muscle cells prevent hemorrhage and blood–brain barrier breakdown at vascular hotspots in juvenile and adult zebrafish.

Trained monocytes alleviate DSS-induced colitis via bacterial clearance and monocyte differentiation reprogramming.

A conserved kinase network links nutrient sensing to chromosome segregation and gene regulation by modulating cohesin dynamics through phosphorylation.

A cognitive adaptation in Heliconius butterflies, accompanied by strikingly divergent changes in two principal insect integration centres, reveals that neural circuits can differ strongly in their propensity for evolutionary change.

ITCH is an important regulator of SARS-CoV-2 life cycle, coordinating ubiquitination, assembly, autophagosome-mediated secretion, and spike stability, highlighting ITCH as a promising therapeutic target for antiviral intervention.

TrASPr+BOS enables accurate prediction and design of tissue-specific RNA splicing, even for tissues not trained on, uncovering unseen regulatory elements and guiding sequence edits that reshape splicing outcomes.