Drosophila female germline tumors mutant for bam or bgcn mimic the stem cell niche to inhibit the differentiation of neighboring wild-type germline stem cells.
Elena Badillo Goicoechea, Phillip F Agres ... Joel L Voss
Meta-analysis indicates that network-targeted non-invasive brain stimulation consistently enhances memory function supported by the hippocampal network, thus providing robust evidence that specific memory abilities rely on specific modifiable brain networks.
A newly developed chemo-immunological strategy enabled detection of acetoacetate-mediated lysine acetoacetylation, identified the associated regulatory enzymes, and revealed its distinct biological functions and physiological significance.
Neural reward signals following effort are amplified for self-benefiting outcomes but attenuated for other-benefiting outcomes, contingent upon reward magnitude and individual effort sensitivity.
The Drosophila ryanodine receptor plays a conserved role in setting functional and structural muscle properties, regulates embryonic muscle development and could be used to assess the impact of human RYR1 mutations.
Dissociable neural signatures of integration and segregation provide the first direct neuroimaging evidence for the integration-segregation theory of exogenous attention.
A biologically plausible reinforcement learning model that integrates associative memory and hippocampal remapping explains context-dependent flexible behavior, neural dynamics, and psychosis-related symptoms.
Mahdiyar Shahbazi, Olivier Codol ... Paul L Gribble
Recurrent neural network models trained on a novel motor skill exhibit a persistent shift in preparatory activity that enables faster relearning, without cognitive or contextual cues.
Lamina I projection neurons that respond selectively to skin cooling receive monosynaptic input from Trpm8-expressing primary afferents and innervate brain regions involved in perception of cold and cold defence mechanisms.
