Andrew C Glover, Hannah Koenker ... Thomas S Churcher
While transmission intensity should still drive where insecticide-treated nets are prioritised, deprioritising areas where people are more likely to use nets may cause larger case resurgences than otherwise expected.
Anastasios Marantos, Kim Sneppen ... Namiko Mitarai
Energy-limited bacterial cells reduce phage adsorption, particularly for weakly binding viruses, revealing host physiology as a key factor in viral commitment to infection.
Spontaneous reactivation of an interrupted biosynthetic gene reveals unexpected plasticity in folate-dependent one-carbon metabolism that promotes growth and virulence in the foodborne human pathogen Listeria monocytogenes.
Brain activity in the pre-supplementary motor area and dorsolateral prefrontal cortex represents gaze-weighted accumulated evidence signals in value-based decision-making.
MOTS-c, a mitochondrial-encoded microprotein, has immunological origins and functions, revealing for the first time that our immune system is encoded by both co-evolved nuclear and mitochondrial genomes.
In a mouse model of E. coli meningitis, non-myeloid TLR4 signaling is a key determinant of the inflammatory response in all leptomeningeal cells and of the increase in vascular permeability.
Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
Latent developmental potential facilitates trait re-evolution with novel phenotypic patterns, adding a new perspective to understanding of the origins of novel traits in evolutionary and developmental biology.
Ali Özgür Argunşah, Tevye Jason Stachniak ... Theofanis Karayannis
Elfn1-mediated synaptic facilitation onto somatostatin-positive interneurons drives the local lateral inhibition required to functionally segregate cortical barrel and septal processing domains in mice.