Browse our Research Articles

Page 2 of 1,484
    1. Neuroscience

    Circadian control of a sex-specific behavior in Drosophila

    Sabrina Riva, Maria Fernanda Ceriani ... Diana Lorena Franco
    A semi-automated system for monitoring egg-laying reveals that lateral dorsal neurons are key regulators of circadian oviposition, showing that the neural circuits controlling oviposition and circadian locomotor behavior are different.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Redirection of SARS-CoV-2 to phagocytes by intranasal sACE2-Fc as a universal decoy confers complete prophylactic protection

    Jingyi Wang, Jiangchuan Li ... Bo Feng
    Functional and mechanistic analyses reveal that intranasal decoys engage phagocytic clearance beyond viral neutralization to provide effective protection, establishing immune redirection for developing broad-spectrum countermeasures against airborne viral threats.
    1. Biochemistry and Chemical Biology

    The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells

    Guillaume Lefrançois, Emilie Lavallée ... Gerardo Ferbeyre
    Biochemical and genetic evidence identifies ATP5I as a biguanide target, redefining biguanide action through ATP synthase regulation and assembly, mitochondrial architecture, and mitochondrial protein turnover.
    1. Neuroscience

    Bilateral equalization of synaptic output in olfactory glomeruli of Xenopus tadpoles

    Marta Casas, Beatrice Terni, Artur Llobet
    A novel bilateral compensatory mechanism important for the activity of olfactory glomeruli in Xenopus tropicalis tadpoles was uncovered.
    1. Genetics and Genomics

    Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

    Slavica Stanojcic, Bridlin Barckmann ... Yvon Sterkers
    Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide composition, G‑quadruplex enrichment, and distinctive nucleosome patterns.
    1. Cancer Biology
    2. Developmental Biology

    Tumors mimic the niche to inhibit neighboring stem cell differentiation

    Yang Zhang, Yuejia Wang ... Shaowei Zhao
    Drosophila female germline tumors mutant for bam or bgcn mimic the stem cell niche to inhibit the differentiation of neighboring wild-type germline stem cells.
    1. Neuroscience

    Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing

    Katrina Bartas, Pieter Derdeyn ... Kevin T Beier
    Addictive drugs, as well as ketamine/xylazine, change the connectivity to ventral tegmental area dopamine cells, which may be related to cellular activity.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Adrenomedullin restores the human cortical interneurons migration defects induced by hypoxia

    Alyssa Puno, Wojciech P Michno ... Anca M Pasca
    Exposure of human cortical interneurons to hypoxia leads to decreased migration, a process that is likely altered in preterm infants and contributes to the increased risk for neurodevelopmental problems.
    1. Neuroscience

    A meta-analysis suggests that TMS targeting the hippocampal network selectively improves episodic memory

    Elena Badillo Goicoechea, Phillip F Agres ... Joel L Voss
    Meta-analysis indicates that network-targeted non-invasive brain stimulation consistently enhances memory function supported by the hippocampal network, thus providing robust evidence that specific memory abilities rely on specific modifiable brain networks.
    1. Neuroscience

    Subregional activity in the dentate gyrus is amplified during elevated cognitive demands

    Charlotte Castillon, Shintaro Otsuka ... Anis Contractor
    Selective engagement of suprapyramidal dentate gyrus neurons during a high-demand pattern separation task reveals blade-specific circuit engagement for enhancing mnemonic discrimination.