Browse our Research Articles

The IFT172 C-terminus bridges IFT-A and IFT-B complexes through mutually exclusive interactions with IFT140 and IFT144, and harbors a U-box-like domain linking intraflagellar transport to ubiquitin-dependent ciliary signaling.

Queuing theory links multiplicity of infection (MOI) to force of infection (FOI), enabling the estimation of transmission intensity for falciparum malaria (and other infectious diseases) from sparsely sampled surveys.

CLas hijacks the DA/DcDop2-miR-31a-AKH-JH signaling cascade to improve D. citri lipid metabolism and fecundity, while simultaneously promoting its replication.

Chemogenetic and in vivo recording approaches reveal how persistent hyperactivity in the posterior paraventricular thalamus promotes sensitization of fear responses to unlearned threats after stress exposure.

Coregulator TR-FRET profiling reveals ligand-specific LXR signaling signatures that can guide the therapeutic design of ABCA1-inducing LXR agonists with attenuated risk of hepatic lipogenesis.

Single-neuron recordings reveal that anterior cingulate cortex and caudate nucleus encode the interaction between rewards, state transitions, and choices that underlies flexible, goal-directed decision-making.

Esr1 directs adolescent transcriptional maturation of medial preoptic GABAergic neurons, enabling the normal development of mating behavior in male and female mice.

Tunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and volume coverage, allowing flexible sampling and measurements of vascular, neuronal, and immune dynamics.

Long-term motor recovery after musculoskeletal alteration relies on gradually developing novel compensatory movements to overcome the rigid, maladaptive timing of stable muscle synergies.

Enterovirus D68, a cause of acute flaccid myelitis, disrupts the composition and function of the nuclear pore complex primarily through its 2A protease, which is also toxic to motor neurons.