Browse our Research Articles

Page 2 of 1,474
    1. Structural Biology and Molecular Biophysics

    Active regulation of the epidermal growth factor receptor by the membrane bilayer

    Shwetha Srinivasan, Xingcheng Lin ... Gabriela S Schlau-Cohen
    Membrane composition modulates EGFR conformational dynamics and signaling, revealing that the bilayer properties can override ligand control to influence receptor activation in health and disease.
    1. Neuroscience

    Fear conditioning biases olfactory sensory neuron frequencies across generations

    Clara W Liff, Yasmine R Ayman ... Bianca J Marlin
    Olfactory fear conditioning biases olfactory stem cell receptor fate, increasing the frequency by which maturing neurons express the receptor of the paired odor and changing the representation of the olfactory sensory neuron landscape in the next generation.
    1. Neuroscience

    Audiovisual cues must be predictable and win-paired to drive risky choice

    Brett A Hathaway, Dexter R Kim ... Catharine Winstanley
    Sensory cues increase risky choice when paired with wins but reduce risky choice when paired with losses, with parallel shifts in sensitivity to negative outcomes.
    1. Neuroscience

    Individuality across environmental context in Drosophila melanogaster

    Thomas F Mathejczyk, Cara Knief ... Gerit A Linneweber
    Environmental differences alter behavioral performance in Drosophila melanogaster without eliminating consistent individual differences.
    1. Neuroscience

    Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain

    Kevin C Lister, Calvin Wong ... Arkady Khoutorsky
    Spinal translational control mechanisms regulate gene expression and nociceptive circuit sensitization during the chronic phase of neuropathic pain.
    1. Immunology and Inflammation

    Contrasting roles for IKK-regulated inflammatory signalling pathways for development and maintenance of type 1 and adaptive γδ T cells

    Farjana Islam, Cayman Williams ... Benedict Seddon
    Inhibitor of κB kinase signalling differentially controls development and survival of γδ T cell subsets through nuclear factor-κB activation and repression of receptor-interacting protein kinase 1-driven necroptosis, revealing distinct inflammatory signalling requirements from αβ T cells.
    1. Neuroscience

    Principles of gamma synchrony predict figure–ground perception in texture stimuli

    Maryam Karimian, Mark Jonathan Roberts ... Mario Senden
    Principles of weakly coupled oscillators capture human figure-ground segregation and its training-induced enhancement, indicating gamma synchrony remains a plausible grouping mechanism.
    1. Neuroscience

    Stimulus dependencies—rather than next-word prediction—can explain pre-onset brain encoding in naturalistic listening designs

    Inés Schönmann, Jakub Szewczyk ... Micha Heilbron
    The ability to predict brain activity from words before they occur can be explained by information shared between neighbouring words, without requiring next-word prediction by the brain.
    1. Cell Biology

    GTPase-activating protein DLC1 spatio-temporally regulates Rho signaling

    Lucien Hinderling, Max Heydasch ... Olivier Pertz
    Mechanosensitive recruitment of DLC1 to focal adhesions creates a positive feedback loop that locally amplifies Rho activation in response to tension.