Browse our Research Articles

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    1. Developmental Biology

    Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells

    Hiroki Tsutsumi, Tomoki Chiba ... Hiroshi Asahara
    Single-cell profiling reveals CD55+CD248+ tendon stem/progenitor cells.
    1. Neuroscience

    A forebrain hub for cautious actions via the midbrain

    Ji Zhou, Muhammad Sarmad Sajid ... Manuel A Castro-Alamancos
    Cautious action timing under threat depends on glutamatergic signaling from the subthalamic nucleus to the midbrain, revealing a circuit mechanism for adaptive goal-directed behavior.
    1. Computational and Systems Biology

    The representation of facial emotion expands from sensory to prefrontal cortex with development

    Xiaoxu Fan, Abhishek Tripathi, Kelly Bijanki
    Facial emotion representations expand from sensory cortex to prefrontal regions across development, suggesting that the prefrontal cortex matures with development to enable a full understanding of facial emotion.
    1. Neuroscience

    Causal evidence for a domain-specific role of left superior frontal sulcus in human perceptual decision-making

    Miguel Barretto-Garcia, Marcus Grueschow ... Christian C Ruff
    Disrupting left superior frontal sulcus selectively impaired perceptual but not value-based decisions, revealing segregated prefrontal circuits for integrating sensory evidence versus subjective preferences in human choice behaviour.
    1. Neuroscience

    Human brain dynamics and spatiotemporal trajectories during threat processing

    Joyneel Misra, Luiz Pessoa
    Intrinsic neural attractors and extrinsic environmental inputs jointly steer the dynamic trajectories of brain activity during threat processing.
    1. Physics of Living Systems

    Feeding rates in sessile versus motile ciliates are hydrodynamically equivalent

    Jingyi Liu, Yi Man ... Eva Kanso
    Fluid flow analysis reveals that both swimming and sessile ciliates achieve competitive nutrient uptake, resolving the long-standing debate over the hydrodynamic advantage of either strategy.
    1. Evolutionary Biology

    Accelerated evolution in networked metapopulations of Pseudomonas aeruginosa

    Partha Pratim Chakraborty, Rees Kassen
    Centralized migration accelerates adaptation and drives parallel evolution, emphasizing the key influence of spatial organization on evolutionary dynamics across systems from pathogen transmission to species range shifts.
    1. Cancer Biology
    2. Cell Biology

    Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function

    Bei Zhang, Ting Cai ... Zhihao Wu
    The carboxyl-terminal alanine-threonine-tailed protein ATP5α helps glioblastoma mitochondria maintain a high membrane potential and keep the permeability transition pore closed, thereby promoting tumor growth and increasing resistance to apoptosis.
    1. Immunology and Inflammation

    Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco-flavored e-cigarette-exposed mouse lungs

    Gagandeep Kaur, Thomas Lamb ... Irfan Rahman
    Profiling cell-specific immune responses reveals altered neutrophil function and enhanced T-cell mediated cell death following acute in vivo exposure to tobacco-flavored e-cigarette aerosol using single-cell technology.
    1. Epidemiology and Global Health

    Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onwards

    Marie-Cécile Dupas, Maria F Vincenti-Gonzalez ... Simon Dellicour
    Post-2020, highly pathogenic avian influenza H5 circulation is characterised by spatially expanded ecological suitability, changes in key environmental predictors, and a wider range of avian species affected.