Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Neuroscience

    Foveated metamers of the early visual system

    William F Broderick, Gizem Rufo ... Eero P Simoncelli
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Cell Biology

    N6-Adenosine Methylation of a Single Site in SARS-CoV-2 5′-UTR Promotes Translation

    Ammar Aly, Gary Scott ... A Pejmun Haghighi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    Preferential formation of NUP98-KDM5A condensates at specific H3K4me3-rich loci drives leukemogenic gene expression

    Augusto Berrocal, Jonathan E Sandoval ... Bo Huang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Optimising the tilt-increment for in situ cryo-electron tomography

    Maarten W Tuijtel, Tomáš Majtner ... Martin Beck
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cancer Biology

    CDK4 or CDK6 upregulation induces DNA replication stress and genomic instability to cause EGFR targeted therapy resistance in lung cancer

    Beatrice Gini, Philippe Gui ... Collin M Blakely
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology

    The structure-interaction model of polymyxin lipopeptides with human oligopeptide transporter 2

    Xukai Jiang, Yining Luo ... Jian Li
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Genetics and Genomics
    2. Evolutionary Biology

    Pre-Cambrian origin of envelope-carrying retrotransposons in metazoans

    Shashank Chary, Rippei Hayashi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins

    Daniel J Kelpsch, Liyun Zhang ... Steven A Farber
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    The C3-C3aR axis modulates trained immunity in alveolar macrophages

    Alexander P Earhart, Alberto Lopez ... Hrishikesh S Kulkarni
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    Adaptive plasticity of aspartate metabolism in succinate dehydrogenase-deficient cancer cells

    David Sokolov, Eric Zheng ... Lucas B Sullivan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete