Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Cell Biology

    Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism

    Fangqing Deng, Rong Yang ... Lianbing Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Evolutionary Biology

    Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotype

    Tom Louis Ducrocq, Damien Laporte, Bertrand Daignan-Fornier
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Impacts of DNA methylation on H2A.Z deposition and nucleosome stability

    Rochelle M Shih, Yasuhiro Arimura ... Hironori Funabiki
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology

    Paternal over- and under-nutrition program fetal and placental development in a sex-specific manner in mice

    Hannah L Morgan, Nader Eid ... Adam J Watkins
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    Deciphering interferon functions in avian influenza: Insights from receptor knockout models in the natural host

    Mohanned Naif Alhussien, Hanna-Kaisa Vikkula ... Benjamin Schusser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Solid
    1. Cell Biology

    Decoupling AMPK from fatty acid synthesis allows maintenance of fitness late in life

    Hanane Hadj-Moussa, Megan Ulusan ... Jonathan Houseley
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A miniaturized MR1 metabolite display system with native-like protein features

    Photis Rotsides, Omkar Shinde ... Nikolaos G Sgourakis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Evolutionary Biology

    Bacterial ancestry of the mitochondrial ATP exporter

    Jotin Gogoi, Rajan Sankaranarayanan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Examining Alzheimer’s Disease modifiable risk factors: Impact of physical activity and diet on neuroanatomy and behaviour in mouse models

    Cindy L García, Chloe Anastassiadis ... M Mallar Chakravarty
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Decentralized Clocks and Direct Photoreception: The Zebrafish as an Integrative Model for Circadian Biology

    Wang Liao, Chun-jiao Wei ... Da-long Ren
    Not revised
    Reviewed Preprint v1