Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Computational and Systems Biology
    2. Stem Cells and Regenerative Medicine

    Combinatorial transcription factor interactions drive modular gene regulatory networks

    Jialei Duan, Boxun Li ... Gary C Hon
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    SETD6-mediated methylation of PPARγ establishes a transcriptional feedback circuit promoting lipid accumulation in liver-derived cells

    Noa Nashnaz, Dana Goldberg ... Dan Levy
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Ecology

    The overall and sequence-specific degradation of soil extracellular DNA fragments: rates and influential factors

    Ting Li, Song Zhang ... Rongxiao Che
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    Sequential adaptor function of Treacle and MDC1 couples nucleolar reorganization to RNF8-dependent recruitment of HDR factors

    Andrea Haenel, Johannes Leyrer ... Manuel Stucki
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    Tolerance to Lung Infection in TWIK2 K+ Efflux Mediated Macrophage Trained Immunity

    Josh Thompson, Yufan Li ... Jingsong Xu
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Cell Biology

    p66Shc Mediates SUMO2-induced Endothelial Dysfunction

    Jitendra Kumar, Shravan K Uppulapu ... Santosh Kumar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    • Solid
    1. Neuroscience

    Distinct neural representations of perceptual and numerical absence in the human brain

    Benjy Barnett, Stephen M Fleming
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    An integrated human forebrain organoid reveals microglia-mediated CD8+ T cell recruitment and neuroimmune dysfunction in Alzheimer’s disease pathology

    Yilin Feng, Feifei Yu ... Shaohua Ma
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    A membrane insertion code for intrinsically disordered proteins

    Fidha Nazreen Kunnath Muhammedkutty, Huan-Xiang Zhou
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Out-of-balance Growth Enables Cost-free Synthesis of the Flagellum and Other Proteins in a Single Bacterium

    Mayra Garcia-Alcala, Josiah C Kratz, Philippe Cluzel
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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