Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Developmental Biology

    Comparative single-cell transcriptomic roadmap of mammalian fetal ovarian development

    Yifei Fang, Shiyao Han ... Jingyue Ellie Duan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Opto-MDMi: a dual-lock optogenetic system for robust activation of endogenous p53

    Tatsuki Tsuruoka, Takashi Sumikama ... Kazuhiro Aoki
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A mitochondrial quality control mechanism reverses the phagosome maturation arrest caused by Mycobacterium tuberculosis

    Surbhi Verma, Shweta Thakur ... Dhiraj Kumar
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Distinct prokaryotic gut microbiome and proviral-immune axes of pathophysiology in Sickle Cell Disease

    Zachary N Flamholz, Jennifer De Los Santos ... Libusha Kelly
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    The cistrome response to hypoxia in human umbilical vein endothelial cells

    Ayush Singh, Viktor Pastukh ... Hank W Bass
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    The openretina Project: Collaborative Retina Modelling Across Datasets and Species

    Federico D’Agostino, Thomas Zenkel ... Matthias Bethge
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Targeting tankyrase scaffolding in the β-catenin destruction complex by PROTAC overcomes the limitation of catalytic inhibitors in cancer

    Qian Wang, Liping Li ... Chuo Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Unexpected plasticity in the life cycle of Trypanosoma brucei

    Carina Praisler, Jaime N Lisack ... Markus Engstler
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Solid
    1. Developmental Biology

    A genetic screen reveals dosage-sensitive effects of ASD genes and identifies domino as a regulator of synaptic and behavioral phenotypes

    Ellen Stirtz, Zachary B Madaj ... Adelheid Lempradl
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Structural basis for site-specific histone H3 acetylation-dependent regulation of RNAPII transcription through nucleosomes

    Takumi Oishi, Suguru Hatazawa ... Hitoshi Kurumizaka
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
Load more