Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Immunology and Inflammation

    ITK Deficiency Attenuates Alveolar Hemorrhage by Enhancing Regulatory T Cell-Mediated Tissue Resilience

    Mohammad Saddam Hossain, Ali Mobeen ... Mobin Karimi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Junctional β-Catenin Stabilization Links Wnt Signaling and Force Generation

    Agimaa Otgonbaatar, Sujithra Shankar ... Nicholas S Tolwinski
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Identifying molecular instructions to hard-wire a sensory neuron’s synaptic connectivity

    Júnia Vieira dos Santos, Renee Yin Yu ... Brian E Chen
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Medicine
    2. Immunology and Inflammation

    TLR4 signaling drives tissue inflammation, Claudin-5 internalization, and vascular barrier breakdown in a mouse model of neonatal meningitis

    Philip V Seegren, Amir Rattner ... Jeremy Nathans
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine

    Mid-zone hepatocytes trade proliferation for survival via Atf4-Chop axis in early acute liver injury

    Yaying Zhu, Chengxiang Deng ... Zhao Shan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Computational and Systems Biology

    Permute-match tests detect significant correlations between time series despite nonstationarity and limited replicates

    Alex E Yuan, Wenying Shou
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Thalamo-accumbal circuit adaptations following extended oxycodone abstinence

    Yanaira Alonso-Caraballo, Yan Li ... Elena H Chartoff
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Compelling
    1. Developmental Biology
    2. Genetics and Genomics

    Multiple Molecular Pathways to Longevity: Opposing Gene Expression Programs Define Distinct Aging Strategies

    Zenith D Rudich, Jiaxi Guan ... Jeremy M Van Raamsdonk
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Excitation–inhibition balance controls coupling stability and network reorganization in a plastic Kuramoto model

    Satoshi Kuroki, Kenji Mizuseki
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cancer Biology

    JAK-STAT Pathway Heterogeneity Governs Immunotherapy Response in Breast Cancer

    Jianbo Zhou, Heng Zhang ... Fu Peng
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Convincing
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