Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Genetics and Genomics
    2. Computational and Systems Biology

    Massively Parallel Polyribosome Profiling Reveals Translation Defects of Human Disease-Relevant UTR Mutations

    Wei-Ping Li, Jia-Ying Su ... Chien-Ling Lin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    In vivo mapping of striatal neurodegeneration in Huntington’s disease with Soma and Neurite Density Imaging

    Vasileios Ioakeimidis, Marco Palombo ... Claudia Metzler-Baddeley
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Structural Biology and Molecular Biophysics

    DIRseq: a method for predicting drug-interacting residues of intrinsically disordered proteins from sequences

    Matthew MacAinsh, Sanbo Qin, Huan-Xiang Zhou
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Dissociation of the nuclear basket triggers chromosome loss in aging yeast

    Mihailo Mirkovic, Jordan McCarthy ... Yves Barral
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Cell Biology
    2. Immunology and Inflammation

    Protein phase change batteries drive innate immune signaling and cell fate

    Alejandro Rodriguez Gama, Tayla Miller ... Randal Halfmann
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    The TTLL10 polyglycylase is stimulated by tubulin glutamylation and inhibited by polyglycylation

    Steven W Cummings, Yan Li ... Antonina Roll-Mecak
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Compelling
    1. Neuroscience

    Observational activation of anterior cingulate cortical neurons coordinates hippocampal replay in social learning

    Xiang Mou, Daoyun Ji
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Orderly mitosis shapes interphase genome architecture

    Krishnendu Guin, Adib Keikhosravi ... Tom Misteli
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Restoring data balance via generative models of T cell receptors for antigen-binding prediction

    Emanuele Loffredo, Mauro Pastore ... Rémi Monasson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Spatially Periodic Computation in the Entorhinal-Hippocampal Circuit During Navigation

    Bo Zhang, Xin Guan ... Jia Liu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete