Cancer Biology

Latest articles

1. 1. Cancer Biology

   Overcoming the nutritional immunity by engineering iron-scavenging bacteria for cancer therapy

   Sin-Wei Huang, See-Khai Lim ... Kurt Yun Mou

   Bacterial therapy can be impeded by nutrition deprivation in the tumor microenvironment, and enhancing bacteria resistance to iron sequestration enhances its antitumoral activity for therapeutic purposes.
2. 1. Cancer Biology
   2. Cell Biology

   Exosomes: How tumors escape the immune system

   Stefanie Schmieder

   Mutations in the gene for β-catenin cause liver cancer cells to release fewer exosomes, which reduces the number of immune cells infiltrating the tumor.
3. 1. Cancer Biology

   Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia

   Kyle Spinler, Michael Hamilton ... Tannishtha Reya
4. 1. Cancer Biology

   Inhibition of ULK1/2 and KRAS^G12C controls tumor growth in preclinical models of lung cancer

   Phaedra C. Ghazi, Kayla T. O’Toole ... Martin McMahon
5. 1. Cancer Biology
   2. Cell Biology

   mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3^IBTK-mediated ubiquitination of eIF4A1 in cancer cells

   Dongyue Jiao, Huiru Sun ... Kun Gao

   Overexpression of inhibitor of Bruton's tyrosine kinase contributes to the process of tumorigenesis by amplifying translation, represents a promising target for anti-cancer therapies.
6. 1. Cancer Biology

   Replication of null results: Absence of evidence or evidence of absence?

   Samuel Pawel, Rachel Heyard ... Leonhard Held

   Equivalence testing and Bayes factors are informative statistical methods for analyzing replication studies of original studies with null results, and can address the limitations of the commonly used non-significance criterion.
7. 1. Cancer Biology
   2. Evolutionary Biology

   High-density sampling reveals volume growth in human tumours

   Arman Angaji, Michel Owusu ... Johannes Berg
8. 1. Cancer Biology

   Unveiling neoadjuvant chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

   Yiwei Huang, Lin Cheng ... Shanye Yin
9. 1. Cancer Biology
   2. Cell Biology

   CYRI-B mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake

   Savvas Nikolaou, Amelie Juin ... Laura M Machesky
10. 1. Cancer Biology

    Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

    Keene L. Abbott, Ahmed Ali ... Matthew G. Vander Heiden