Browse our latest Evolutionary Biology articles

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    1. Cancer Biology
    2. Evolutionary Biology

    Punctuated mutagenesis promotes multi-step evolutionary adaptation in human cancers

    Christopher Graser, Wenbo Wu ... Franziska Michor
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Evolutionary Biology

    Trained immunity and immune priming in plants and invertebrates

    Joachim Kurtz, Raul Andino ... Jurriaan Ton
    An evolutionary perspective on immune priming across plants and invertebrates highlights the roles of microbiomes and epigenetic regulation in shaping innate immune memory with promising applications in agriculture and aquaculture.
    1. Evolutionary Biology

    Coenzyme-protein interactions since early life

    Alma Carolina Sanchez Rocha, Mikhail Makarov ... Klára Hlouchová
    Amino acids that were abundant since the prebiotic era are enriched in protein binding sites of the most ancient coenzymes, supporting the plausibility of an early coenzyme–peptide world.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The primate Major Histocompatibility Complex as a case study of gene family evolution

    Alyssa Lyn Fortier, Jonathan K Pritchard
    The Major Histocompatibility Complex region evolves via gene birth-and-death, resulting in short-lived genes, rapidly expanding gene subfamilies, and many gene fragments.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Pre-Cambrian origin of envelope-carrying retrotransposons in metazoans

    Shashank Chary, Rippei Hayashi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Ecology
    2. Evolutionary Biology

    Fitness drivers of division of labor in vertebrates

    Irene García-Ruiz, Dustin Rubenstein
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Evolutionary Biology

    High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains

    Caroline Kikawa, Andrea N Loes ... Jesse D Bloom
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Evolutionary Biology

    Evolution of gene expression in seasonal environments

    Shuichi N Kudo, Yuka Ikezaki ... Akiko Satake
    A comparative analysis of genome-wide seasonal gene expression dynamics across four forest tree species revealed that a shared 'molecular calendar' emerges in winter, constraining gene expression evolution and potentially limiting temporal niche partitioning and species divergence in seasonal environments.
    1. Developmental Biology
    2. Evolutionary Biology

    HoxB-derived hoxba and hoxbb clusters are essential for the anterior–posterior positioning of zebrafish pectoral fins

    Morimichi Kikuchi, Renka Fujii ... Akinori Kawamura
    HoxB-dependent anterior–posterior patterning and the evolutionary origin of pectoral fins.
    1. Evolutionary Biology

    Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies

    Kai S Shimagaki, Rebecca M Lynch, John P Barton
    Fitness constraints on the HIV envelope protein are highly similar in humans and rhesus macaques, emphasizing the utility of macaque models of infection and antibody development.