The novel pre-training framework integrating sequential and geometric encoders significantly enhances protein engineering by accurately predicting variant effects and thermostability, outperforming existing zero-shot learning methods with minimal computational cost.
A built-in solution for correcting optical aberrations in long (> 6 mm) gradient index (GRIN) lenses enables unbiased two-photon functional recordings of large neuronal populations in the deep mouse brain.
Sulfakinin-receptor1 signaling system alters the expression of odorant receptors in antenna to modulate the behavioral switch between foraging and mating in the oriental fruit fly.
