Research Articles

Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.

Latest articles

    1. Ecology

    The neuropeptide sulfakinin is a peripheral regulator of insect behavioral switch between mating and foraging

    Hong-Fei Li, Bao Dong ... Hong-Bo Jiang
    Sulfakinin-receptor1 signaling system alters the expression of odorant receptors in antenna to modulate the behavioral switch between foraging and mating in the oriental fruit fly.
    1. Computational and Systems Biology

    Semantical and geometrical protein encoding toward enhanced bioactivity and thermostability

    Yang Tan, Bingxin Zhou ... Liang Hong
    The novel pre-training framework integrating sequential and geometric encoders significantly enhances protein engineering by accurately predicting variant effects and thermostability, outperforming existing zero-shot learning methods with minimal computational cost.
    1. Neuroscience

    Temporal dynamics analysis reveals that concurrent working memory load eliminates the Stroop effect through disrupting stimulus-response mapping

    Yafen Li, Yixuan Lin ... Antao Chen
    The concurrent working memory load influences the Stroop conflict processing during the later stage of stimulus-response mapping.
    1. Neuroscience

    GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine

    Takashi Yamamoto, Kayoko Ueji ... Shinya Ugawa
    The enhanced taste and flavor of food induced by the addition of L-ornithine, referred to as 'kokumi' in humans, may be mediated by GPRC6A receptors expressed in taste cells.
    1. Neuroscience

    Neural geometry from mixed sensorimotor selectivity for predictive sensorimotor control

    Yiheng Zhang, Yun Chen ... He Cui
    Target motion modulates monkey M1 neural dynamics during reaching, characterized by an orbital neural geometry composed of target-velocity-dependent tilting rings, suggesting that sensory information can be independently incorporated during motor generation.
    1. Physics of Living Systems

    Physiological magnetic field strengths help magnetotactic bacteria navigate in simulated sediments

    Agnese Codutti, Mohammad A Charsooghi ... Stefan Klumpp
    Microfluidics experiments and simulations show that magnetotactic bacteria are adapted to the geomagnetic field strength for optimal navigation in sediment environments.
    1. Neuroscience

    Perceptual and attentional impairments of conscious access involve distinct neural mechanisms despite equal task performance

    Samuel Noorman, Timo Stein ... Simon van Gaal
    When performance is matched, the attentional blink allows for greater integration of complex stimulus features than masking, reflecting spared recurrent processing during attentional versus perceptual impairments of conscious access.
    1. Evolutionary Biology
    2. Neuroscience

    The first complete 3D reconstruction and morphofunctional mapping of an insect eye

    Anastasia A Makarova, Nicholas J Chua ... Alexey A Polilov
    Even the smallest compound eyes retain the functional specialization of ommatidia.
    1. Evolutionary Biology

    Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticity

    William R Thomas, Troy Richter ... Liliana M Davalos
    Adaptive gene expression in the common shrew hypothalamus connects energy homeostasis with reversible brain size changes in response to seasonal environmental challenges.
    1. Microbiology and Infectious Disease

    Complex system modeling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteria

    Sromona D Mukherjee, Carlos Batagello ... Aaron W Miller
    Microbiome composition through the redundancy of oxalate-degrading bacteria, critically influence oxalate metabolism, explaining variable outcomes of Oxalobacter formigenes therapy and offers insights for improving probiotic selection and clinical trial strategies.