Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Developmental Biology

    Cell Signaling: Not all dimers are equal

    Jeet H Patel, Mary C Mullins
    Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.
    Version of Record
    Insight
    1. Developmental Biology

    Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila

    Pengzhen Dong, Yue Li ... Hai Huang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Transcriptome profiling of tendon fibroblasts at the onset of embryonic muscle contraction reveals novel force-responsive genes

    Pavan K Nayak, Arul Subramanian, Thomas F Schilling
    Muscle contraction forces shape tenocyte gene expression, with sequencing and spatial analyses revealing unique force-dependent gene regulation patterns, suggesting tenocytes fine-tune tendon matrix in response to varied mechanical cues.
    1. Developmental Biology

    An atypical basement membrane forms a midline barrier during left-right asymmetric gut development in the chicken embryo

    Cora Demler, John C Lawlor ... Natasza A Kurpios
    A novel midline barrier is discovered in the developing gut, highlighting its dynamics and function, with broad implications for patterning mechanisms, extracellular matrix significance, and laterality disorders.
    1. Developmental Biology

    The epididymis contributes to sperm DNA integrity and early embryo development through Cysteine-Rich Secretory Proteins

    Valeria Sulzyk, Ludmila Curci ... Patricia S Cuasnicu
    The identification of epididymal proteins relevant for sperm DNA integrity and early embryo development will contribute to a better understanding, diagnosis, and treatment of human infertility.
    1. Developmental Biology
    2. Neuroscience

    In mice, discrete odors can selectively promote the neurogenesis of sensory neuron subtypes that they stimulate

    Kawsar Hossain, Madeline Smith ... Stephen W Santoro
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Bcl11b orchestrates subcerebral projection neuron axon development via cell-autonomous, non-cell-autonomous, and subcellular mechanisms

    Yasuhiro Itoh, Mollie B Woodworth ... Jeffrey D Macklis
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Premature vision drives aberrant development of response properties in primary visual cortex

    Sophie V Griswold, Stephen D Van Hooser
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Transcriptional complexity in the insect central complex: single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts

    Derek Epiney, Gonzalo N Morales Chaya ... Chris Q Doe
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing

Senior editors

  1. Albert Cardona
    University of Cambridge, United Kingdom
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors