Browse our Research Articles

A new approach uses heat-induced antigen retrieval to enable tissue clearing, multiple-round immunostaining, and expansion microscopy for volumetric imaging of centimeter-scale clinical formalin-fixed paraffin-embedded specimens.

Efficient myogenic and lipogenic transdifferentiation of chicken fibroblasts in 3D culture produces meat with precisely controlled levels of intramuscular fat and extracellular matrix.

Serum exosomal sequencing combined with cell and animal experiments indicate that miRNA-199b-5p is a novel miRNA associated with osteoarthritis (OA) and can modulate the onset and progression of the disease.

Interplay between multiple Legionella pneumophila effector proteins lead to spatial and temporal regulation of the host Rab10 localization to the bacterial vacuole by controlling noncanonical ubiquitin modifications.

Entomophthora muscae has one of the largest fungal genomes (1.03 Gb) owing to extensive proliferation of transposable elements.

A complete mutational scan of a protein-DNA interface shows that pairwise epistatic interactions among amino acids determine a transcription factor's specificity for DNA and facilitate the evolution of new functions.

Enterococcus faecalis infection elicits a cellular response marked by novel bacterial-host interactions, revealing insights into immune evasion mechanisms in chronic wound infections.

HSCB could be activated by PI3K signaling to facilitate FOG1 nuclear translocation to promote human erythropoiesis and megakaryopoiesis, highlighting an important, previously unrecognized iron–sulfur cluster delivery independent function of HSCB.

A novel neurodevelopmental role for FMRP in collaboration with MAP1B, jointly orchestrating neuronal migration by influencing the microtubular cytoskeleton.