Inter-individual stereotypy of the Platynereis larval visual connectome
- Max Planck Institute for Developmental Biology, Germany
Abstract
Developmental programs have the fidelity to form neural circuits with the same structure and function among individuals of the same species. It is less well understood, however, to what extent entire neural circuits of different individuals are similar. In a previous paper (Randel et al., 2014) we reported the neuronal connectome of the visual eye circuit from the head of a Platynereis dumerilii larva. We now report a full-body serial section transmission electron microscopy (ssTEM) dataset of another larva of the same age, for which we describe the connectome of the visual eyes and the larval eyespots. Anatomical comparisons and quantitative analyses of the two circuits reveal a high inter-individual stereotypy of the cell complement, neuronal projections and synaptic connectivity, including the left-right asymmetry in the connectivity of some neurons. Our work shows the extent to which the eye circuitry in Platynereis larvae is hard-wired.
Article and author information
Author details
Reviewing Editor
- Eve Marder, Brandeis University, United States
Version history
- Received: April 17, 2015
- Accepted: June 9, 2015
- Accepted Manuscript published: June 10, 2015 (version 1)
- Version of Record published: June 23, 2015 (version 2)
Copyright
© 2015, Randel et al.
This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.
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Inter-individual stereotypy of the Platynereis larval visual connectome
eLife 4:e08069.
https://doi.org/10.7554/eLife.08069
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