Cancer Biology

Latest articles

1. 1. Cancer Biology

   Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids

   Yanping Li, Xiaoxin Xie ... Qionghua Zhu
2. 1. Cancer Biology
   2. Computational and Systems Biology

   Systematic analysis of network-driven adaptive resistance to CDK4/6 and oestrogen receptor inhibition using meta-dynamic network modelling

   Anthony Hart, Sung-Young Shin, Lan K Nguyen

   Meta Dynamic Network analysis can identify the capacity of a network to facilitate adaptive drug resistance and the respective underlying mechanistic causes.
3. 1. Cancer Biology

   A senescent-immune reserve niche model for incomplete lobular involution in the aging breast

   Jaida C Lue, Darren J Baker ... Derek C Radisky
4. 1. Cancer Biology

   Nerve Injury-Induced Protein 2 preserves lysosomal membrane integrity to suppress ferroptosis

   Jin Zhang, Miranda Bustamante ... Xinbin Chen
5. 1. Computational and Systems Biology
   2. Cancer Biology

   dbGIST: An LLM-Assisted Multi-Omics Resource for Target Exploration and Cross-Dataset Validation in Gastrointestinal Stromal Tumors

   Zhao Sun, Qian Zhao ... Yang Fu
6. 1. Cancer Biology
   2. Medicine

   A novel prognostic score based on carbohydrate antigen 125, alpha-fetoprotein and carcinoembryonic antigen for Predicting postoperative prognosis in endometrial cancer: Results from a retrospective cohort study

   Zi-hao Wang, Qing Li ... Xiao-xin Ma
7. 1. Developmental Biology
   2. Cancer Biology

   A Rare Nestin-Expressing Granule Cell Precursor Subpopulation Underlies SHH Medulloblastoma Formation

   Salsabiel El Nagar, Yinwen Liang ... Alexandra L Joyner
8. 1. Cancer Biology

   Heterotypic interfacial tension between oncogenic and wild-type populations forms the mechanical basis of tissue-specific oncogenesis in epithelia

   Amrapali Datta, Phanindra Dewan ... Medhavi Vishwakarma

   Mechanical interactions at the interface of mutant and wild-type cell populations govern tissue-specific responses to oncogenic transformation in epithelia, causing mutants to be extruded, spatially restrained, or undergo persistent expansion.
9. 1. Cell Biology
   2. Cancer Biology

   Slap restricts oncogenic Src-family kinase signaling to maintain colonic epithelial homeostasis

   Dana Naim, Zouheir Houhou ... Serge Roche
10. 1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis

    Patrick B Jonker, Mumina Sadullozoda ... Alexander Muir

    Modeling the metabolic microenvironment of pancreatic tumors leads to the identification of polyunsaturated fatty acid metabolism as a vulnerability of pancreatic cancer.