Cancer Biology

Latest articles

1. 1. Cancer Biology

   Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas

   Anne Fajac, Iva Simeonova ... Franck Toledo

   The male-specific tumor-suppressive effects of minor p53 isoforms were correlated with higher Ackr4 expression levels, which have implications for sex-specific cancer prognosis in humans.
2. 1. Cancer Biology
   2. Structural Biology and Molecular Biophysics

   Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain

   Gabriella O Estevam, Edmond M Linossi ... James S Fraser

   Deep mutational scanning reveals interactions in the MET kinase domain that are critical for regulation and cancer-related signaling.
3. 1. Cancer Biology

   Engineering PEG10-assembled endogenous virus-like particles with genetically encoded neoantigen peptides for cancer vaccination

   Ruijing Tang, Luobin Guo ... Xiaolong Liu

   ePAC, a novel cancer vaccine utilizing a mammalian-derived virus-like particle to co-deliver neoantigens and CpG-ODN, demonstrates strong antitumor efficacy in mouse models.
4. 1. Cancer Biology
   2. Stem Cells and Regenerative Medicine

   Regulation of lung cancer initiation and progression by the stem cell determinant Musashi

   Alison G Barber, Cynthia M Quintero ... Tannishtha Reya
5. 1. Medicine
   2. Cancer Biology

   Development and Assessment of a Sustainable PhD Internship Program Supporting Diverse Biomedical Career Outcomes

   Patrick D Brandt, Dawayne Whittington ... Rebekah L Layton
6. 1. Cancer Biology

   The T Cell Receptor β Chain Repertoire of Tumor Infiltrating Lymphocytes Improves Neoantigen Prediction and Prioritization

   Thi Mong Quynh Pham, Thanh Nhan Nguyen ... Le Son Tran
7. 1. Cancer Biology

   Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway

   Elazar Besser, Anat Gelfand ... David Meiri

   The cannabinoids cannabidiol, cannabidivarin, and the newly identified 331-18A demonstrate antitumoral effects in Notch1-mutated leukemia, underscoring the potential and complexity of Cannabis as a novel treatment for cancer.
8. 1. Cancer Biology

   Targeting ribosome biogenesis as a novel therapeutic approach to overcome EMT-related chemoresistance in breast cancer

   Yi Ban, Yue Zou ... Dingcheng Gao

   Inhibiting the RiBi pathway impedes both EMT and MET processes, enhancing chemotherapy efficacy and presenting a novel avenue to tackle advanced breast cancer treatment resistance.
9. 1. Computational and Systems Biology
   2. Cancer Biology

   Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data

   Aurélie AG Gabriel, Julien Racle ... David Gfeller
10. 1. Cancer Biology

    TAK1-mediated phosphorylation of PLCE1 represses PIP2 hydrolysis to impede esophageal squamous cancer metastasis

    Qianqian Ju, Wenjing Sheng ... Cheng Sun