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    1. Structural Biology and Molecular Biophysics

    Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments

    Sofia Lövestam, Jane L Wagstaff ... Sjors HW Scheres
    Phosphomimetic mutations allow the assembly of full-length recombinant tau into Alzheimer's paired helical filaments by disrupting intramolecular contacts between its ordered core and fuzzy coat.
    1. Structural Biology and Molecular Biophysics

    ProteinConformers: large-scale and energetically profiled descriptions of protein conformational landscapes

    Yihang Zhou, Chen Wei ... Yang Zhang
    Not revised
    Reviewed Preprint v1
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    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    RNA Selectively Modulates Activity of Virulent Amyloid PSMα3 and Host Defense LL-37 via Phase Separation and Aggregation Dynamics

    Bader Rayan, Eilon Barnea ... Meytal Landau
    Revised
    Reviewed Preprint v2
    Updated
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    1. Structural Biology and Molecular Biophysics

    Binding Entropy Can Be Predicted by Crystallographic Ensembles

    Charlotte A Miller, Stephanie A Wankowicz
    Not revised
    Reviewed Preprint v1
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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    ATP-driven conformational dynamics reveal hidden intermediates in a heterodimeric ABC transporter

    Matija Pečak, Christoph Nocker, Robert Tampé
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    Reviewed Preprint v1
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    1. Structural Biology and Molecular Biophysics

    Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

    Nevin K Zacharia, Stefanie Kuhns ... Esben Lorentzen
    Revised
    Reviewed Preprint v2
    Updated
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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into the recruitment of viral Type 2 IRES to ribosomal preinitiation complex for protein synthesis

    Deepakash Das, Tanweer Hussain
    Revised
    Reviewed Preprint v2
    Updated
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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Natural xanthones as α-Mangostin induce vasorelaxation involving key gating residues in the S6 domain of BK channels

    Soenke Cordeiro, Robert Patejdl ... Marianne A Musinszki
    Identification of mangostins as potent BK channel activators links natural xanthones to vascular smooth muscle relaxation, providing a mechanistic basis for their reported antihypertensive effects.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Defining the Antigenic Topology and Prospective Binding Breadth of Vaccination-induced SARS-CoV-2 Neutralizing Antibodies

    Deepika Jaiswal, Clara G Altomare ... Goran Bajic
    Not revised
    Reviewed Preprint v1
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    1. Structural Biology and Molecular Biophysics

    Cryo-EM structure of the bicarbonate receptor GPR30

    Shota Kaneda, Airi Jo-Watanabe ... Osamu Nureki
    Revised
    Reviewed Preprint v3
    Updated
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