Genes and chromosomes

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A stable tetrameric nucleosome occupies the central segment of each ∼120-bp budding yeast centromere in two rotational phases of both reflectional orientations in vivo.
Steven Henikoff, Srinivas Ramachandran, Kristina Krassovsky, Terri D Bryson, Christine A Codomo, Kristin Brogaard, Jonathan Widom, Ji-Ping Wang, Jorja G Henikoff
10.7554/eLife.01861
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The acetylation of histones at specific sites close to DNA can regulate transcription.
Vincenzo Di Cerbo, Fabio Mohn, Daniel P Ryan, Emilie Montellier, Salim Kacem, Philipp Tropberger, Eleni Kallis, Monika Holzner, Leslie Hoerner, Angelika Feldmann, Florian Martin Richter, Andrew J Bannister, Gerhard Mittler, Jens Michaelis, Saadi Khochbin, Robert Feil, Dirk Schuebeler, Tom Owen-Hughes, Sylvain Daujat, Robert Schneider
10.7554/eLife.01632
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A novel complex composed of various components of a chromatin remodeling complex, a chromatin remodeling factor and a transcription factor suppresses the dedifferentiation of intermediate neural progenitors back into neuroblasts in Drosophila.
Chwee Tat Koe, Song Li, Fabrizio Rossi, Jack Jing Lin Wong, Yan Wang, Zhizhuo Zhang, Keng Chen, Sherry Shiying Aw, Helena E Richardson, Paul Robson, Wing-Kin Sung, Fengwei Yu, Cayetano Gonzalez, Hongyan Wang
10.7554/eLife.01906
Experiments on E. coli show that multiple mechanisms contribute to extreme resistance to ionizing radiation in bacteria, with mutations to three genes for DNA repair having a prominent role in one evolved population.
Rose T Byrne, Audrey J Klingele, Eric L Cabot, Wendy S Schackwitz, Jeffrey A Martin, Joel Martin, Zhong Wang, Elizabeth A Wood, Christa Pennacchio, Len A Pennacchio, Nicole T Perna, John R Battista, Michael M Cox
10.7554/eLife.01322

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