Genes and chromosomes

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The need for efficient pre-RNA splicing during early embryonic development of Drosophila indicates that the constraints imposed by the cell cycle are a force capable of driving changes in Eukaryotic gene architecture.
Leonardo Gastón Guilgur, Pedro Prudêncio, Daniel Sobral, Denisa Liszekova, André Rosa, Rui Gonçalo Martinho
10.7554/eLife.02181
A stable tetrameric nucleosome occupies the central segment of each ∼120-bp budding yeast centromere in two rotational phases of both reflectional orientations in vivo.
Steven Henikoff, Srinivas Ramachandran, Kristina Krassovsky, Terri D Bryson, Christine A Codomo, Kristin Brogaard, Jonathan Widom, Ji-Ping Wang, Jorja G Henikoff
10.7554/eLife.01861
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The acetylation of histones at specific sites close to DNA can regulate transcription.
Vincenzo Di Cerbo, Fabio Mohn, Daniel P Ryan, Emilie Montellier, Salim Kacem, Philipp Tropberger, Eleni Kallis, Monika Holzner, Leslie Hoerner, Angelika Feldmann, Florian Martin Richter, Andrew J Bannister, Gerhard Mittler, Jens Michaelis, Saadi Khochbin, Robert Feil, Dirk Schuebeler, Tom Owen-Hughes, Sylvain Daujat, Robert Schneider
10.7554/eLife.01632
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