Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Evolutionary Biology

    Latent gene network expression underlies partial re-evolution of a polyphenic trait in the worker caste of ants

    Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Gcn5 – mTORC1 – TFEB signalling axis mediated control of autophagy regulates Drosophila blood cell homeostasis

    Arjun Aji Reeja, Mincy Kunjumon ... Rohan Jayant Khadilkar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    The microtubule-binding protein EML3 is required for mammalian embryonic growth and cerebral cortical development, and Eml3 null mice are a model of cobblestone brain malformation

    Isabelle Carrier, Eduardo Diez ... Roderick McInnes
    Absence of EML3 in mice leads to delayed embryonic development, small size, perinatal lethality, and the over-migration of neuroblasts due to a defective pial basement membrane.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure.
    1. Developmental Biology

    Trpv4 links environmental temperature to testicular differentiation in hermaphroditic ricefield eel

    Yang Zhi, Luo Tingting ... Sun Yuhua
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells

    Volker Soltys, Moritz Peters ... Yingguang Frank Chan
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Solid
    1. Developmental Biology

    Genome-wide discovery of cis-regulatory elements in a large genome

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology

    Ectopic hAMH-driven SOX17 expression induces hyperplastic Sertoli valve formation in mouse testes

    Xiao Han, Aya Uchida ... Yoshiakira Kanai
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    In vitro sexual dimorphism establishment in schistosomes

    Rémi Pichon, Magda E Lotkowska ... Gabriel Rinaldi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Wunen(s) help navigate Primordial Germ Cells by attenuating Hedgehog signaling

    Amrita Roy, Adheena Elsa Roy ... Girish Deshpande
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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Highlights

    1. Developmental Biology

    Oocyte Development: The discovery of the mammalian fusome

    Michael Buszczak, Anirban Dasgupta
    1. Developmental Biology
    2. Genetics and Genomics

    Written out of history

    Lisa M Thomann, Julie Batut
    1. Developmental Biology

    Limb Patterning: The cellular logic of limb regeneration

    Matthew Cherubino, Catherine D McCusker

Senior editors

  1. Albert Cardona
    University of Cambridge, United Kingdom
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors