Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics

    Mutational and Expression Profile of ZNF217, ZNF750, ZNF703 Zinc Finger Genes in Kenyan Women Diagnosed with Breast Cancer

    Michael Kitoi, John Gitau ... Francis Makokha
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics

    Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila

    Xiaoyu Wu, Xingzhuo Yang ... Juan Du
    The Mettl5/Trmt112 complex alters rRNA methylation, increasing PERIOD protein linking ribosome function, clock genes, and proteasome in sleep regulation in Drosophila.
    1. Genetics and Genomics
    2. Cancer Biology

    Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8

    Hyunkyung Kong, Jiyeon Choi ... Kevin M Brown
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Genetics and Genomics

    Adapting clinical chemistry plasma as a source for liquid biopsies

    Spencer C Ding, Jingru Yu ... Wei Gu
    Residual plasma from rapid routine clinical chemistry tubes enables cell-free DNA NGS-based analysis, providing an untapped, scalable, and accessible resource without specialized collection workflows.
    1. Genetics and Genomics

    Identification of a somatic H3K23me3 methyltransferase SET-19 in C. elegans

    Mingjing Xu, Zixue Fan ... Xuezhu Feng
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Optics-free reconstruction of shapes, images and volumes with DNA barcode proximity graphs

    Hanna Liao, Sanjay Kottapalli ... Sanjay Srivatsan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    The causes and consequences of human-specific DNA methylation

    Zhenzhen Ma, Alexander L Starr ... Hunter B Fraser
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Incomplete
    1. Genetics and Genomics
    2. Immunology and Inflammation

    GM-CSF regulates ILC states and myeloid cell signaling during ulceration in Crohn’s disease

    Joshua K Morrison, Ksenija Sabic ... Ling-shiang Chuang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Neuroscience

    Oxytocin receptor controls promiscuity and development in prairie voles

    Ruchira Sharma, Kristen M Berendzen ... Devanand S Manoli
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Genetics and Genomics
    2. Medicine

    Point of View: Teaching early-career researchers how to respond to peer reviewers

    Eric Kalkhoven, Manon Kluijtmans
    Responding to reports from peer reviewers is a crucial part of scientific publishing, but early-career researchers are rarely taught about this process.
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Highlights

    1. Genetics and Genomics
    2. Medicine

    How to respond to peer reviewers

    Eric Kalkhoven, Manon Kluijtmans
    1. Developmental Biology
    2. Genetics and Genomics

    Written out of history

    Lisa M Thomann, Julie Batut
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Chromosomes: Finding a role for non-coding DNA in trypanosomes

    Markus R Schmidt

Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Murim Choi
    Seoul National University College of Medicine, South Korea
  3. Yamini Dalal
    National Cancer Institute, United States
  4. See more editors