Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Zebrafish Rif1 impacts zygotic genome activation, replication timing, and sex determination

    Emily A Masser, Tyler D Noble ... Christopher L Sansam
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Evolutionary Biology
    2. Genetics and Genomics

    Intersecting experimental evolution and CRISPR screens to identify novel toxin resistance loci

    Michele Marconcini, Steeve Cruchet ... Richard Benton
    Selection of animal populations and of cultured cells provides complementary datasets to identify candidate genes involved in conferring resistance to a natural insecticide.
    1. Genetics and Genomics

    Environmental Learning: How experience shapes individuality

    Bassem A Hassan
    Behavioural diversity across fruit flies changes with individual learning, even when genetic, past and momentary environmental factors are held constant.
    Version of Record
    Insight
    1. Genetics and Genomics

    The genetic control of rapid genome content divergence in Arabidopsis thaliana

    Christopher J Fiscus, Daniel Koenig
    Repeat variation in wild Arabidopsis thaliana arises from centromere-proximal sequence changes and rare variants in DNA replication, repair, and methylation genes, consistent with purifying selection constraining genome expansion.
    1. Genetics and Genomics

    AGES for Ageing: Evaluating the auxin-inducible gene expression system for use in Drosophila ageing studies

    Taylor McGilvary, Kriti Gupta ... Nathan Woodling
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Determining the off-target activity of antibiotics and novel translation initiation sites in mitochondria

    James Marks, Emma Young, Markus Hafner
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Separable downmodulation of meiotic axis protein deposition and DNA break induction at chromosome ends

    Adhithi R Raghavan, Kieron May ... Andreas Hochwagen
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Ecology

    Plasticity Associated with Adoption of Social Roles in Clown Anemonefish

    Lili F Vizer, Douglas Alvarado ... Peter M Buston
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics

    Resetting of H3K4me2 during mammalian parental-to-zygote transition

    Chong Wang, Yang Li ... Jiawei Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Optics-free reconstruction of shapes, images and volumes with DNA barcode proximity graphs

    Hanna Liao, Sanjay Kottapalli ... Sanjay Srivatsan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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Highlights

    1. Genetics and Genomics
    Microscopy image of a fruit fly. Image credit: USGS (CC0)

    How experience shapes individuality

    Bassem A Hassan
    1. Genetics and Genomics
    2. Medicine

    Responding to peer reviewers

    Eric Kalkhoven, Manon Kluijtmans
    1. Developmental Biology
    2. Genetics and Genomics

    Written out of history

    Lisa M Thomann, Julie Batut

Senior editors

  1. Murim Choi
    Seoul National University College of Medicine, South Korea
  2. Yamini Dalal
    National Cancer Institute, United States
  3. Detlef Weigel
    Max Planck Institute for Developmental Biology, Germany
  4. See more editors