Insights

Latest articles

1. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Virus Evolution: Scaling up efforts to target evolving viruses

   Lin Wang, Henrik Salje

   High-throughput neutralisation tests could lead to a better understanding of the evolution of human influenza.
2. 1. Developmental Biology

   Oocyte Development: The discovery of the mammalian fusome

   Michael Buszczak, Anirban Dasgupta

   The presence of an organelle called the fusome in species as diverse as Drosophila and mammals indicates an ancient, conserved programme of germ cell development.
3. 1. Neuroscience

   Temporal Information: Synaptic footprints of time in working memory

   Dhruv Grover, Marissa L Heintschel

   Temporary changes in synapses may allow working memory to keep track of both events and their timing.
4. 1. Neuroscience

   Brain Mapping: Redefining borders in the sensorimotor cortex

   Sylvain Crochet

   Experiments mapping individual neurons in the sensorimotor cortex of mice show that sharp transitions in functional properties can define cortical regions.
5. 1. Structural Biology and Molecular Biophysics

   Receptor Proteins: Lipids challenge ligands to control receptors

   Adam JM Wollman

   The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.
6. 1. Medicine
   2. Structural Biology and Molecular Biophysics

   Medical Imaging: MRI sets its sights on collagen

   Fritz Schick

   Reducing the echo time of a whole-body MRI scanner makes it possible to image collagen, an important structural protein found in bones and tendons.
7. 1. Developmental Biology

   Limb Patterning: The cellular logic of limb regeneration

   Matthew Cherubino, Catherine D McCusker

   Hierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.
8. 1. Neuroscience

   Aging: Linking neuron-glia interactions and longevity

   Michael Pokrass, Nan Hao

   Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.
9. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Chromosomes: Finding a role for non-coding DNA in trypanosomes

   Markus R Schmidt

   Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.
10. 1. Cancer Biology
    2. Cell Biology

    Chemotherapy: Lipid balance and chemoresistance in cancer cells

    Kaori Kanemaru, Yoshikazu Nakamura

    A shift in the balance between two lipids – cholesterol and sphingomyelin – makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.