Cell Biology

Latest articles

1. 1. Cell Biology

   Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

   Ewa K Bomba-Warczak, Karen M Velez ... Francesca E Duncan

   Exceptionally long-lived macromolecules in mammalian ovaries and oocytes serve as pillars for lifelong reproductive health span.
2. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Hundreds of myosin 10s are pushed to the tips of filopodia and could cause traffic jams on actin

   Julia Shangguan, Ronald S Rock

   Improved technology for counting proteins captures myosin 10 dynamics throughout the filopodial lifecycle, defines requirements for initiating filopodia, and reveals a crowded filopodial tip where motors frequently exceed available actin.
3. 1. Cancer Biology
   2. Cell Biology

   Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα

   Francesca Butera, Julia E Sero ... Chris Bakal

   A live imaging and computational approach reveals feedback loops involving F-actin dynamics that regulate the NF-κB transcription factor RELA.
4. 1. Cell Biology
   2. Chromosomes and Gene Expression

   The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing crossover formation in C. elegans

   Bhumil Patel, Maryke Grobler ... Needhi Bhalla
5. 1. Cell Biology
   2. Developmental Biology

   The exocyst complex controls multiple events in the pathway of regulated exocytosis

   Sofía Suárez Freire, Sebastián Pérez-Pandolfo ... Mariana Melani
6. 1. Cell Biology

   Protein absorption in the zebrafish gut is regulated by interactions between lysosome rich enterocytes and the microbiome

   Laura Childers, Esther Park ... Michel Bagnat
7. 1. Cell Biology
   2. Computational and Systems Biology

   De novo-designed minibinders expand the synthetic biology sensing repertoire

   Zara Y Weinberg, Sarah S Soliman ... Hana El-Samad
8. 1. Cell Biology
   2. Neuroscience

   Rab11 suppresses neuronal stress signaling by localizing dual leucine zipper kinase to axon terminals for protein turnover

   Seung Mi Kim, Yaw Quagraine ... Jung Hwan Kim

   Coupling between subcellular localization and protein turnover of a neuronal stress kinase, DLK, and its role in neuronal stress responses in Drosophila.
9. 1. Cell Biology
   2. Neuroscience

   Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion

   Lu Yang, Zijin Lin ... Li Liu

   The established triple co-culture blood-–brain barrier (BBB) model could be used for predicting drugs’ BBB permeability, and co-culture with neurons and astrocytes enhanced brain endothelial cells’ integrity by secreting GDNF, which upregulated claudin-5 and VE-cadherin expression.
10. 1. Cell Biology

    Image Correlation Spectroscopy is a Robust Tool to Quantify Cellular DNA Damage Response

    Angelica A Gopal, Bianca Fernandez ... J Matthew Dubach