Microbiology and Infectious Disease

Latest articles

1. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   A novel high-throughput single-cell DNA sequencing method reveals hidden genomic heterogeneity in the unicellular eukaryote Leishmania

   Gabriel H Negreira, Pieter Monsieurs ... Malgorzata A Domagalska
2. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response

   Long-Feng Lu, Can Zhang ... Shun Li

   CDK2-mediated TBK1 degradation via Dtx4 represents a previously unrecognized regulatory mechanism that modulates antiviral immunity in fish.
3. 1. Microbiology and Infectious Disease

   ATP burst is the dominant driver of antibiotic lethality in Mycobacterium smegmatis

   Tejan Lodhiya, Aseem Palande ... Raju Mukherjee

   Multiomics and biochemical studies reveal that excess ATP levels, and not ROS, is the dominant driver for antibiotic cidality in Mycobacterium smegmatis.
4. 1. Microbiology and Infectious Disease

   Pathogen-Phage Geomapping to Overcome Resistance

   Camilla Do, Keiko C Salazar ... Anthony W Maresso
5. 1. Microbiology and Infectious Disease

   The PPE2 protein of Mycobacterium tuberculosis is responsible for the development of hyperglycemia and insulin resistance during tuberculosis

   Manoj Kumar Bisht, Vandana Maurya ... Sangita Mukhopadhyay
6. 1. Microbiology and Infectious Disease

   Heterogeneity of genetic sequence within quasi-species of influenza virus revealed by single-molecule sequencing

   Kenji Tamao, Hiroyuki Noji, Kazuhito Tabata

   High-accuracy single-molecule unique molecular identifier sequencing reveals non-random, biologically driven mutation heterogeneity within influenza quasi-species, enabling precise profiling of intra-host viral evolutionary potential.
7. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

   Chiara Tomasini, Celine Cuche ... Francesca Di Nunzio

   HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.
8. 1. Microbiology and Infectious Disease

   A dual role for PGLYRP1 in host defense and immune regulation during B. pertussis infection

   David M Rickert, Sasha Cardozo ... Ciaran Skerry
9. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Deletion of the moeA gene in Flavobacterium IR1 drives structural color shift from green to blue and alters polysaccharide metabolism

   Álvaro Escobar Doncel, Constantinos Patinios ... Colin J Ingham

   Disrupting a single molybdenum cofactor gene allowed us to connect metabolic regulation of complex carbohydrates with cell organization, enabling genetic tuning of bacterial structural color for biomaterial applications.
10. 1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Neisseria gonorrhoeae LIN codes provide a robust, multi-resolution lineage nomenclature

    Anastasia Unitt, Made A Krisna ... Odile B Harrison

    LIN code offers a reliable framework for classifying gonococcal population structure, enabling straightforward exploration of isolate relationships, from broad superlineage divisions to minute single allele differences.