Microbiology and infectious disease

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Predicting the pandemic potential of influenza viruses from genetic sequence data could transform pandemic risk assessment but progress towards this goal will require the integration of experimental work, computational tools, and virus surveillance.
Colin A Russell, Peter M Kasson, Ruben O Donis, Steven Riley, John Dunbar, Andrew Rambaut, Jason Asher, Stephen Burke, C Todd Davis, Rebecca J Garten, Sandrasegaram Gnanakaran, Simon I Hay, Sander Herfst, Nicola S Lewis, James O Lloyd-Smith, Catherine A Macken, Sebastian Maurer-Stroh, Elizabeth Neuhaus, Colin R Parrish, Kim M Pepin, Samuel S Shepard, David L Smith, David L Suarez, Susan C Trock, Marc-Alain Widdowson, Dylan B George, Marc Lipsitch, Jesse D Bloom
10.7554/eLife.03883
Measuring HIV-1 DNA levels at the time of stopping antiretroviral therapy (when initiated during primary infection) predicts clinical progression and the time taken for plasma viraemia to become detectable.
James P Williams, Jacob Hurst, Wolfgang Stöhr, Nicola Robinson, Helen Brown, Martin Fisher, Sabine Kinloch, David Cooper, Mauro Schechter, Giuseppe Tambussi, Sarah Fidler, Mary Carrington, Abdel Babiker, Jonathan Weber, Kersten K Koelsch, Anthony D Kelleher, Rodney E Phillips, John Frater
10.7554/eLife.03821

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