Microbiology and Infectious Disease

Latest articles

1. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   A novel high-throughput single-cell DNA sequencing method reveals hidden genomic heterogeneity in the unicellular eukaryote Leishmania

   Gabriel H Negreira, Pieter Monsieurs ... Malgorzata A Domagalska
2. 1. Ecology
   2. Microbiology and Infectious Disease

   Tracking West Nile virus dynamics using viral loads from trapped mosquitoes

   Punya Alahakoon, Ian Marchinton ... James A Hay

   Mosquito-pool Ct values reflect biologically meaningful variation in viral load, while integrating viral kinetics improves prevalence estimates and helps distinguish potentially infectious from non-infectious mosquitoes.
3. 1. Microbiology and Infectious Disease

   Mycobacterium tuberculosis suppresses protective Th17 responses during infection

   Alex Zilinskas, Amir Balakhmet ... Sarah A Stanley

   Mycobacterium tuberculosis uses its type VII secretion system and surface lipid phthiocerol dimycocerosate to suppress protective host Th17 cell responses.
4. 1. Microbiology and Infectious Disease

   Bird Flu: The cow udder as an influenza mixing ground

   Silke Rimaux, Robert P de Vries

   Bovine mammary tissue can support infection and replication of diverse influenza A viruses and may provide an environment in which different viral strains can co-infect cells.
5. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Intracellular growth of Chlamydia trachomatis leads to global histone hypermethylation by impairing demethylation

   Chloé I Charendoff, Félix V Louchez ... Agathe Subtil

   The metabolic pressure exerted by a pathogen with an intracellular lifestyle drives epigenetic modifications, which modulate the transcriptional response of the host to infection.
6. 1. Microbiology and Infectious Disease

   SIRT2 protects against Japanese encephalitis virus infection in mice

   Perumal Arumugam Desingu, Lavanya Dindi ... Nagalingam R Sundaresan
7. 1. Structural Biology and Molecular Biophysics
   2. Microbiology and Infectious Disease

   Structures of LolB bound to LolA or lipoprotein resolve the final steps of bacterial lipoprotein trafficking

   Abigail E Jepson, Elise Kaplan ... Vassilis Koronakis
8. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Obtaining maximum information from colony counts with REPOP

   Pedro Pessoa, Carol Yunxiao Slayton ... Steve Presse

   Conventional colony counting obscures bacterial population structure by conflating biological heterogeneity with stochastic noise from dilution and plating, which can be separated by explicitly modeling the measurement process.
9. 1. Microbiology and Infectious Disease

   The structural context of mutations in proteins predicts their effect on antibiotic resistance

   Anna G Green, Mahbuba Tasmin ... Maha Reda Farhat

   Spatial clustering of mutations in Mycobacterium tuberculosis proteins finds proteins that are involved in antibiotic resistance, and predicts which mutations cause resistance.
10. 1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    RelB proximity proteomics and CRISPR screening define chromatin regulators of noncanonical NF-κB control of HIV latency and reactivation

    Cameron R Bussey-Sutton, Carley N Gray ... Brian D Strahl