A Short Report allows authors to publish the results of a small number of experiments, provided the conclusion is clear and justified, and the findings are novel and judged to be of high importance.
Loss of endothelial Slit2 removes the chemo-attractive signal needed for Robo1-positive sympathetic axons to follow coronary vessels, resulting in reduced ventricular innervation.
Caleb CS Calhoun, Mary ES Capps ... Summer B Thyme
Sensitive brain activity mapping and behavioral profiling reveal most microexons are dispensable for early brain development but highlight a small subset with intriguing neural phenotypes for future study.
Jessel Ayra Plasencia, Sara Medina-Suárez ... Félix Machín
The cohesin subunit Scc1 returns and reconstitutes the complex with Smc1–Smc3 in late mitosis upon DNA double-strand breaks, although it does not participate in homologous recombination-driven MAT switching.
The uplift of the Qinghai-Tibet Plateau redirected avian migrations from latitudinal to longitudinal paths through induced monsoon systems, fundamentally reshaping continental biogeographic patterns.
Full-length, autoinhibited LRRK2 assembles into distinct, shorter microtubule-bound filaments via a previously unobserved N-terminal repeat interface, revealing new structural states with potential therapeutic implications.
scRNA+TCR-seq technology identifies a high proportion of dual TCR Treg cells in both lymphoid and non-lymphoid tissues of mice, revealing their tissue specificity, TCR repertoire characteristics, and functional phenotypes.
Evidence for H. naledi and increasing recognition of meaning-making behavior across the later Pleistocene suggests that the hominin emotional, socio-cognitive niche is broader and more significant than previously thought.
Climbing fiber activity gates the acquisition phase of motor learning but becomes nonessential for memory consolidation or performance once proficiency is achieved.
Marie-Alphée Laurent, Corentin Jacques ... Bruno Rossion
There is a striking correspondence between face-selective neural increases vs decreases of fMRI BOLD signal and spikes in neighboring human fusiform gyrus regions.
