The plant developmental regulator GNOM performs its unique function from the cell periphery, through sequence features present in all its domains, and not by the control of endocytosis.
Changyu Zhu, Yadira M Soto-Feliciano ... Scott W Lowe
Epigenetic regulator MLL3 is mutated and lost in human hepatocellular carcinoma due to its ability to activate a well-defined tumor suppressor and cell death in transformed cells.
SNARE proteins are delivered as complexes already from the endoplasmic reticulum along the secretory pathway to the cell division plane to mediate the formation of the partitioning membrane by vesicle fusion.
Calcium influx stimulates formation of ER/plasma membrane contacts adjacent to focal adhesions, and lipid transfer at these sites is required for adhesion disassembly during cell migration.