Browse our latest Cell Biology articles

Page 2 of 323
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Functionally-Coupled Ion Channels Begin Co-assembling at the Start of Their Synthesis

    Roya Pournejati, Jessica M Huang ... Oscar Vivas
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology

    Septins function in exocytosis via physical interactions with the exocyst complex in fission yeast cytokinesis

    Davinder Singh, Yajun Liu ... Jian-Qiu Wu
    Protein–protein interactions and localization dependencies between septin cytoskeleton and the exocyst complex using the fission yeast model system reveal one of the most conserved functions of septins in exocytosis.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Chromosomes: Exploring a crossroads in the aging process

    Kiyan Shabestary, Daniel E Gottschling
    Experiments on yeast show that the nuclear pore complex has a central role in the loss of chromosomes associated with aging.
    Version of Record
    Insight
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Dissociation of the nuclear basket triggers chromosome loss in aging yeast

    Mihailo Mirkovic, Jordan McCarthy ... Yves Barral
    Aging results in remodeling of the nuclear pore complex and leakage of intron-containing pre-mRNA out of the nucleus, altering gene function and mitotic stability of old cells.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Cell membrane glycan contents are biochemical factors that constitute a kinetic barrier to viral particle uptake in a protein-nonspecific manner

    Yoshihisa Kaizuka, Rika Machida
    Intermolecular steric repulsion generated by glycans on the cell membrane inhibits viral infection by preventing the formation of a virus-cell interface, regardless of the identity of molecules for glycan modification.
    1. Cell Biology

    Deep3DSIM: Super-resolution imaging of thick tissue using 3D structured illumination with adaptive optics

    Jingyu Wang, Danail Stoychev ... Ilan Davis
    Deep3DSIM enables super-resolution imaging >130 µm into complex tissues of fixed and live specimens in an upright configuration, allowing sample manipulation, as well as rapid refocusing without the need to move the specimen or objective lens.
    1. Cell Biology

    The Rab7-Epg5 and Rab39-ema modules cooperatively position autophagosomes for efficient lysosomal fusions

    Attila Boda, Villő Balázs ... Péter Lőrincz
    An RNAi based genetic screen and subsequent analyses reveal how dyneins and small GTPases coordinate autophagosome positioning at the ncMTOC in fat cells, advancing understanding of autophagic vesicle transport.
    1. Cell Biology

    Dominant spinal muscular atrophy linked mutations in the cargo binding domain of BICD2 result in altered interactomes and dynein hyperactivity

    Hannah Neiswender, Jessica E Pride ... Graydon B Gonsalvez
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Suppression of interferon signaling via small molecule modulation of TFAM

    Dionisia P Sideris, Hsuan Lee ... Lin Lyu
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete