Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics

    Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes

    Lee-Ann Notice-Sarpaning, Mathieu Catala ... Ambro van Hoof
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    Gene expression variation across genetically identical individuals predicts reproductive traits

    Amy K Webster, John H Willis ... Patrick C Phillips
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Genetics and Genomics

    Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome

    Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape

    Ursula E Schoeberl, Johanna Fitz ... Rushad Pavri
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Refining the resolution of the yeast genotype-phenotype map using single-cell RNA-sequencing

    Arnaud N’Guessan, Wen Yuan Tong ... Alex N Nguyen Ba
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Atherosclerosis, Intracranial Aneurysms, and Intermediate Biomarkers: Real-World Observational and Mendelian Randomization Research

    Wei Liu, Zhaoxu Zheng ... Dong Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Transcriptional coregulation in cis around a contact insulation site revealed by single-molecule microscopy

    Maciej A Kerlin, Ilham Aboulfath-Ladid ... Antoine Coulon
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics

    Molecular requirements for C. elegans transgenerational epigenetic inheritance of pathogen avoidance

    Rachel Kaletsky, Rebecca S Moore ... Coleen T Murphy
    Deviating from established protocols is the most likely reason why Gainey et al. (2024) could not reproduce earlier results in a Caenorhabditis elegans transgenerational inheritance paradigm, and the earlier findings are also supported by tests with over 30 new genes.
    Version of Record
    Short Report
    • Fundamental
    • Compelling
    1. Genetics and Genomics
    2. Neuroscience

    Rapid and Inducible Mislocalization of Endogenous TDP43 in a Novel Human Model of Amyotrophic Lateral Sclerosis

    Johanna Ganssauge, Sophie Hawkins ... Akshay Bhinge
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cancer Biology
    2. Genetics and Genomics

    Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer

    Arkajyoti Bhattacharya, Thijs S Stutvoet ... Rudolf SN Fehrmann
    Independent component analysis of ovarian cancer transcriptomes reveals distinct transcriptional patterns associated with overall survival.
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