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    1. Medicine

    Senescence of endplate osteoclasts induces sensory innervation and spinal pain

    Dayu Pan, Kheiria Gamal Benkato ... Xu Cao
    1. Biochemistry and Chemical Biology
    2. Medicine

    Bone canonical Wnt signaling is downregulated in type 2 diabetes and associates with higher advanced glycation end-products (AGEs) content and reduced bone strength

    Giulia Leanza, Francesca Cannata ... Nicola Napoli
    In individuals with type 2 diabetes, downregulation of bone canonical Wnt signaling is linked to higher levels of advanced glycation end-products within the bone, contributing to lower bone strength.
    1. Medicine

    Current perspectives on the multiple roles of osteoclasts: Mechanisms of osteoclast–osteoblast communication and potential clinical implications

    Valentina Daponte, Katrin Henke, Hicham Drissi
    A comprehensive review focusing on the role of osteoclasts as active regulators of bone homeostasis by influencing osteoblast function explores the currently known mechanisms and coupling factors involved in osteoclast–osteoblast communication and their potential as treatments for bone diseases.
    1. Medicine

    Identification of Novel Syncytiotrophoblast Membrane Extracellular Vesicles Derived Protein Biomarkers in Early-onset Preeclampsia: A Cross-Sectional Study

    Toluwalase Awoyemi, Shuhan Jiang ... Manu Vatish
    1. Medicine

    Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis

    Sindre Lee-Ødegård, Marit Hjorth ... Kåre I. Birkeland
    1. Medicine

    Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study

    Ruijie Zeng, Yuying Ma ... Hao Chen
    1. Medicine

    Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia

    Ling Zhou, Chengyang Ni ... Jianming Wu
    Vilazodone could bind to the 5-Hydroxtrayptamine receptor 1A receptor and further regulate the SRC/MAPK signaling pathway to facilitate megakaryocyte differentiation and platelet production.
    1. Medicine

    A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria

    Tumininu S. Faniyan, Xinyi Zhang ... Kavaljit H. Chhabra
    1. Medicine

    Cell-autonomous and non-cell-autonomous effects of arginase-II on cardiac aging

    Duilio M. Potenza, Xin Cheng ... Xiu-Fen Ming
    1. Medicine
    2. Immunology and Inflammation

    Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced diastolic dysfunction

    Yuki Tatekoshi, Chunlei Chen ... Hossein Ardehali
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