Browse the latest research

18,493 results found
    1. Cell Biology

    Altair-LSFM: A High-Resolution, Easy-to-Build Light-Sheet Microscope for Sub-Cellular Imaging

    John Haug, Seweryn Gałecki ... Kevin M Dean
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Neuroscience

    Functional Connectivity-based Attractor Dynamics in Rest, Task, and Disease

    Robert Englert, Balint Kincses ... Tamas Spisak
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Phospholipid scramblase 1 (PLSCR1) regulates interferon-lambda receptor 1 (IFN-λR1) and IFN-λ signaling in influenza A virus (IAV) infection

    Alina Xiaoyu Yang, Lisa Ramos-Rodriguez ... Yang Zhou
    PLSCR1 is an IFN-λ-stimulated gene that enhances IFN-λR1 expression at both transcriptional and protein level, highlighting the potential for targeting PLSCR1 pathways in anti-influenza therapy.
    1. Immunology and Inflammation

    Class A scavenger receptor MARCO negatively regulates Ace expression and aldosterone production

    Conan JO O'Brien, Giorgio Ratti ... Ana I Domingos
    Loss of class A scavenger receptor MARCO results in elevated lung Ace expression and elevated plasma aldosterone concentrations in male mice, demonstrating an endocrine function of this immune scavenger receptor.
    1. Neuroscience

    Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex

    Louis Richevaux, Dongkyun Lim ... Desdemona Fricker
    Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal compass.
    1. Structural Biology and Molecular Biophysics

    Nucleosome wrapping energy in CpG islands and the role of epigenetic base modifications

    Rasa Giniūnaitė, Rahul Sharma ... Daiva Petkevičiūtė-Gerlach
    CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
    1. Chromosomes and Gene Expression

    Structural characterisation of chromatin remodelling intermediates supports linker DNA dependent product inhibition as a mechanism for nucleosome spacing

    Amanda L Hughes, Ramasubramanian Sundaramoorthy, Tom Owen-Hughes
    1. Developmental Biology
    2. Neuroscience

    Cell cycle-dependent cues regulate temporal patterning of the Drosophila central brain neural stem cells

    Gonzalo N Morales Chaya, Mubarak Hussain Syed
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Developmental Biology

    Dorsoventral-mediated Shh induction is required for axolotl limb regeneration

    Sakiya Yamamoto, Saya Furukawa ... Akira Satoh
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Developmental Biology

    Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in C. elegans

    Marilina Raices, Fabiola Balmir ... Judith L Yanowitz
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Solid
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