Air pollution activates macrophage-derived artemin, sensitizing TRPA1 nociceptors to drive neutrophilic asthma, revealing new therapeutic targets for refractory airway inflammation.
Psilocin induces a durable neuroplastic state in human cortical neurons by enhancing BDNF signaling, neurite complexity, synaptogenesis, and synaptic network activity through 5-HT2A receptor-dependent mechanisms.
Rigorous analysis in two knockout mouse lines demonstrates that death receptor 6 is not required for axon degeneration or Schwann cell injury responses following peripheral nerve transection.
