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18,543 results found
    1. Chromosomes and Gene Expression

    The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements

    Andria Koulle, Oluwaseun Ogundele ... Brian Hendrich
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Structural Biology and Molecular Biophysics

    Active regulation of the epidermal growth factor receptor by the membrane bilayer

    Shwetha Srinivasan, Xingcheng Lin ... Gabriela S Schlau-Cohen
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology

    Specialisation of meiotic kinetochores revealed through a synthetic SAC strategy

    Lori B Koch, Christos Spanos, Adele L Marston
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Bruce suppresses autophagy-regulated caspase activity and wing tissue growth in Drosophila

    Natsuki Shinoda, Yutaro Hama ... Masayuki Miura
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Efficient transduction of pancreas tissue slices with genetically encoded calcium integrators

    Charles S Lazimi, Austin E Stis ... Edward A Phelps
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Permissive and instructive Hox codes govern limb positioning

    Yajun Wang, Maik Hintze ... Ruijin Huang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Evolutionary Biology

    Rapid evolution of fine-scale recombination during domestication: a perspective from population genomics

    Zheng-Xi Liu, Ming Li ... Ming-Shan Wang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    • Inadequate
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Effects of residue substitutions on the cellular abundance of proteins

    Thea K Schulze, Kresten Lindorff-Larsen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    A Forebrain Hub for Cautious Actions via the Midbrain

    Ji Zhou, Muhammad S Sajid ... Manuel A Castro-Alamancos
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics

    Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

    Nicholas Tolman, Taibo Li ... Simon WM John
    Single-cell transcriptomics identifies three discrete mouse trabecular meshwork subtypes and demonstrates that an Lmx1b glaucoma mutation drives mitochondrial dysfunction and elevated intraocular pressure, which is lessened by vitamin B3 supplementation.
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