Browse the latest research

19,116 results found
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Targeting tankyrase scaffolding in the β-catenin destruction complex by PROTAC overcomes the limitation of catalytic inhibitors in cancer

    Qian Wang, Liping Li ... Chuo Chen
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Structured stabilization in recurrent neural circuits through inhibitory synaptic plasticity

    Dylan Festa, Claudia Cusseddu, Julijana Gjorgjieva
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Split-trial analysis reveals the information capacity of neural population codes

    Dylan Le, Xue-Xin Wei
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Demonstrating the ability of GABAergic cells in the zona incerta to modulate motivation

    Laura Korobkova, Brian G Dias
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Flexible brain state engagement predicts cognitive control transdiagnostically

    Jean Ye, Saloni Mehta ... Dustin Scheinost
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Rapid cortical reorganization tracks goal-directed sensorimotor learning in real time

    Anthony Renard, Georgios Foustoukos ... Carl CH Petersen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Cancer Biology

    RAB14-dependent tubulovesicular recycling directs MET to invadopodia, promoting TNBC cell invasion

    Amrita Khamari, Atreyee Guria ... Sunando Datta
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression
    2. Physiology

    Gene dosage imbalance disrupts systemic metabolism in the Dp16 Down syndrome mouse model

    Fangluo Chen, Muzna Saqib ... G William Wong
    Gene dosage imbalance due to the triplication of human chromosome 21 gene orthologs impairs whole-body glucose and lipid metabolism by disrupting homeostatic processes across major metabolic tissues.
    1. Neuroscience

    Correction: cxcl18b-defined transitional state-specific nitric oxide drives injury-induced Müller glia cell-cycle re-entry in the zebrafish retina

    Aojun Ye, Shuguang Yu ... Chang Chen
    1. Neuroscience

    Toothy: an interactive platform for dentate spike curation

    Kathleen N Esfahany, Amanda L Schott ... Jordan S Farrell
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
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