Browse the latest research

18,690 results found
    1. Cell Biology

    Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis

    Changle Zhao, Yongxun Chen ... Jing Wei
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Designing optimal perturbation inputs for system identification in neuroscience

    Mikito Ogino, Daiki Sekizawa ... Masafumi Oizumi
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Evolutionary Biology

    Inference of germinal center evolutionary dynamics via simulation-based deep learning

    Duncan K Ralph, Athanasios G Bakis ... Frederick A Matsen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Automated genome mining predicts structural diversity and taxonomic distribution of peptide metallophores across bacteria

    Zachary L Reitz, Bita Pourmohsenin ... Marnix Medema
    Automated detection of metallophore biosynthesis reveals that metal-chelating non-ribosomal peptides are widespread, chemically diverse, and deeply rooted in bacterial evolution.
    1. Neuroscience

    Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced mechanical pain hypersensitivity

    Riku Kawanabe-Kobayashi, Sawako Uchiyama ... Makoto Tsuda
    Stress activates a locus coeruleus–spinal dorsal horn noradrenergic circuit that drives mechanical pain hypersensitivity through Hes5-positive astrocytes.
    1. Developmental Biology
    2. Genetics and Genomics

    Drosophila melanogaster model of RVCL-S demonstrates age dependent disease progression

    Elena Gracheva, Abigail Matt ... Chao Zhou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Anesthesia Lowers Spatial Frequency Preference in the Primary Visual Cortex

    Jiahao Wu, Taisuke Yoneda ... Yumiko Yoshimura
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Should I stay or should I go? Spatiotemporal dynamics of bacterial biofilms in confined flows

    Massinissa Benbelkacem, Gabriel Ramos ... Yohan Davit
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics
    2. Evolutionary Biology

    Faroese Whole Genomes Provide Insight into Ancestry and Recent Selection

    Iman Hamid, Ólavur Mortensen ... Noomi O Gregersen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Microbiology and Infectious Disease

    Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation

    Simone Margaard Offersen, Signe Adamberg ... Anders Brunse
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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