Fidel Emmanuel Serrano, Bianca Ruppert ... Michael Brunner
In light of recent observations of how CK1δ is dynamically regulated, kinase activity and abundance are also regulated throughout the cell cycle primarily through phosphorylation at the C-terminal tail.
Gluconeogenesis rescues insects from glycogen phosphorylase suppression, establishing metabolic redundancy as a key consideration for insecticide target selection.
Glutamine drives its own synthetase to assemble into inhibitory filaments, linking product concentration directly to a conformational switch that gates the active site.
