Biochemistry and Chemical Biology

Latest articles

1. 1. Biochemistry and Chemical Biology

   DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids

   Emily L Dearlove, Chatrin Chatrin ... Danny T Huang
2. 1. Biochemistry and Chemical Biology

   Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

   Nelson García-Vázquez, Tania J González-Robles ... Sharon Kaisari
3. 1. Biochemistry and Chemical Biology

   Early Steps of Protein Disaggregation by Hsp70 Chaperone and Class B J-Domain Proteins are Shaped by Hsp110

   Wiktoria Sztangierska, Hubert Wyszkowski ... Agnieszka Kłosowska
4. 1. Biochemistry and Chemical Biology

   Immunotherapy: The power lies in the glycans

   Luca Unione, Jesús Jiménez-Barbero

   Glycans play an important role in modulating the interactions between natural killer cells and antibodies to fight pathogens and harmful cells.
5. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins

   Kristina Ehring, Sophia Friederike Ehlers ... Kay Grobe

   A composite hedgehog release model that incorporates and supports a previously disparate set of observations has been presented.
6. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Isobaric crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and complexes

   Jie Luo, Jeff Ranish
7. 1. Biochemistry and Chemical Biology
   2. Genetics and Genomics

   Genome-wide mapping of native co-localized G4s and R-loops in living cells

   Ting Liu, Xing Shen ... Zhihong Xue
8. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Hundreds of myosin 10s are pushed to the tips of filopodia and could cause traffic jams on actin

   Julia Shangguan, Ronald S Rock
9. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Point of View: Teaching troubleshooting skills to graduate students

   Gina Partipilo, Yang Gao ... Benjamin K Keitz

   Pipettes and Problem Solving is an initiative that teaches some of the skills needed to figure out why an experiment is producing unexpected results.
10. 1. Biochemistry and Chemical Biology
    2. Plant Biology

    Structure and evolution of alanine/serine decarboxylases and the engineering of theanine production

    Hao Wang, Biying Zhu ... Zhaoliang Zhang

    Comparative structural analysis and biochemical characterization unraveled the mechanisms behind enzymatic substrate selectivity, leading to an amplified theanine yield through active mutant protein screening, thus refining strategies for theanine production.