Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Trained immunity in the lung

   Elina Idiiatullina, Dane Parker

   Several studies have now demonstrated that trained immunity occurs in the airways to several pathogens and products, while its utility is yet to be determined.
2. 1. Cell Biology
   2. Immunology and Inflammation

   The Anti-Inflammatory Role of GPNMB in Post-Traumatic Osteoarthritis

   Asaad A Al-Adlaan, Bryson Cook ... Fayez F Safadi
3. 1. Immunology and Inflammation

   Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism

   Wesley H Godfrey, Judy J Lee ... Michael D Kornberg

   The glycolytic enzyme phosphoglycerate mutase supports Treg function, identifying a novel therapeutic target for immune modulation and demonstrating that glycolytic regulation of T cells is more nuanced than previously appreciated.
4. 1. Genetics and Genomics
   2. Immunology and Inflammation

   ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice

   Chong Chen, Qian Liu ... Xinting Liu
5. 1. Immunology and Inflammation

   Bioengineering approaches to trained immunity: Physiologic targets and therapeutic strategies

   Hannah Riley Knight, Marie Kim ... Aaron Esser-Kahn

   Current approaches in bioengineering are synthesized and methods for their implementation are suggested for the induction and modulation of trained immunity in the treatment of human diseases.
6. 1. Immunology and Inflammation

   A dual nature of γδ T cell immune memory responses

   Tsz Kin Suen, Burcu Al ... Katarzyna Placek

   Both adaptive and innate immune memory responses have been described in gamma delta T cells, yet the mechanisms, the ligands and the gamma delta T cell subsets generating memory responses have remain to be explored.
7. 1. Immunology and Inflammation
   2. Neuroscience

   Photoreceptor loss does not recruit neutrophils despite strong microglial activation

   Derek Power, Justin Elstrott, Jesse Schallek

   Systemic neutrophils do not respond to laser-induced photoreceptor damage despite the robust response from resident microglia.
8. 1. Immunology and Inflammation

   Layilin regulates Treg motility and suppressive capacity in skin

   Victoire Gouirand, Sean Clancy ... Michael D Rosenblum

   Regulatory T cell expression of layilin mediates adhesion in skin, which acts to attenuate their suppressive capacity.
9. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Correlates of protection against African swine fever virus identified by a systems immunology approach

   Kirill Lotonin, Francisco Brito ... Artur Summerfield
10. 1. Immunology and Inflammation

    scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues

    Yuanyuan Xu, Qi Peng ... Xinsheng Yao