Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation
   2. Neuroscience

   Trained immunity in acute and chronic neurological diseases

   Sijia Zhang, Arthur Liesz

   Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation across neurological diseases, offering new insights into disease mechanisms and potential therapeutic strategies.
2. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   The long non-coding RNA Dreg1 is required for optimal ILC2 development

   Sara Quon, Adelynn Tang ... Rhys S Allan
3. 1. Medicine
   2. Immunology and Inflammation

   PDL-1+ Neutrophils mediate susceptibility during endotoxemia in Metabolically Dysfunctional-Associated Fatty Liver Disease

   Cleyson da Cruz Oliveira Barros, Alexandre Kanashiro ... Fernando Queiroz Cunha
4. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response

   Long-Feng Lu, Can Zhang ... Shun Li

   CDK2-mediated TBK1 degradation via Dtx4 represents a previously unrecognized regulatory mechanism that modulates antiviral immunity in fish.
5. 1. Immunology and Inflammation

   A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency

   Yuji Miyatake, Takeshi Kamakura ... Ai Kotani
6. 1. Immunology and Inflammation

   A co-evolutionary perspective on humans and Mycobacterium tuberculosis in the era of systems biology

   Michaela T Reichmann, Liku B Tezera ... Paul T Elkington

   The deep evolutionary relationship between humans and Mycobacterium tuberculosis suggests latent infection may confer benefit, with important consequences for investigating and interpreting host–pathogen interactions.
7. 1. Immunology and Inflammation

   Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs

   Gagandeep Kaur, Thomas Lamb ... Irfan Rahman
8. 1. Immunology and Inflammation
   2. Evolutionary Biology

   Separating selection from mutation in antibody language models

   Frederick A Matsen, Will Dumm ... Hugh K Haddox
9. 1. Cell Biology
   2. Immunology and Inflammation

   Male-Biased Cyp17a2 Orchestrates Antiviral Sexual Dimorphism in Fish via STING Stabilization and Viral Protein Degradation

   Long-Feng Lu, Bao-jie Cui ... Shun Li
10. 1. Immunology and Inflammation

    Epidermal resident memory T cell fitness requires antigen encounter in the skin

    Eric S Weiss, Toshiro Hirai ... Daniel H Kaplan

    Antigen-driven TCR signaling in the epidermis during CD8⁺ T_RM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal T_RM fitness.