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Immunology

Immunology

eLife publishes research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Decisions are made by journal editors who are active researchers in the field of immunology.

 

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Showing results 1 - 10 of 107
A lipid mediator lysophosphatidic acid (LPA) derived from fibroblastic reticular cells regulates T-cell movement through the densely packed reticular network in lymph nodes in a manner dependent on the LPA receptor LPA2-ROCK-myosin II.
Akira Takeda, Daichi Kobayashi, Keita Aoi, Naoko Sasaki, Yuki Sugiura, Hidemitsu Igarashi, Kazuo Tohya, Asuka Inoue, Erina Hata, Noriyuki Akahoshi, Haruko Hayasaka, Junichi Kikuta, Elke Scandella, Burkhard Ludewig, Satoshi Ishii, Junken Aoki, Makoto Suematsu, Masaru Ishii, Kiyoshi Takeda, Sirpa Jalkanen, Masayuki Miyasaka, Eiji Umemoto
10.7554/eLife.10561
The interplay between the cytokine TGFβ and the PD-1/PD-L1 pathway promotes CD8+ T cell anergy and tolerance towards transplanted tissues.
Marije Baas, Alix Besançon, Tania Goncalves, Fabrice Valette, Hideo Yagita, Birgit Sawitzki, Hans-Dieter Volk, Emmanuelle Waeckel-Enée, Benedita Rocha, Lucienne Chatenoud, Sylvaine You
10.7554/eLife.08133
PDGFRα+ Sca-1+ bone marrow stromal/stem cells in whole bone marrow grafts can trigger the onset of autoimmune-related fibrosis in a mouse model of scleroderma.
Yoko Ogawa, Satoru Morikawa, Hideyuki Okano, Yo Mabuchi, Sadafumi Suzuki, Tomonori Yaguchi, Yukio Sato, Shin Mukai, Saori Yaguchi, Takaaki Inaba, Shinichiro Okamoto, Yutaka Kawakami, Kazuo Tsubota, Yumi Matsuzaki, Shigeto Shimmura
10.7554/eLife.09394
Innate lymphoid cells, which are dynamic under steady-state conditions, respond to a colitogenic stimulus by mobilizing from cryptopatches and secreting GM-CSF to organize the pro-inflammatory response.
Claire Pearson, Emily E Thornton, Brent McKenzie, Anna-Lena Schaupp, Nicky Huskens, Thibault Griseri, Nathaniel West, Sim Tung, Benedict P Seddon, Holm H Uhlig, Fiona Powrie
10.7554/eLife.10066
Accepted manuscript
Nima Etemadi, Michael Chopin, Holly Anderton, Maria C Tanzer, James A Rickard, Waruni Abeysekra, Cathrine Hall, Sukhdeep K Spall, Bing Wang, Yuquan Xiong, Timothy Hla, Stuart M Pitson, Claudine S Bonder, Wendy Wei-Lynn Wong, Matthias Ernst, Gordon K Smyth, David L Vaux, Stephen L Nutt, Ueli Nachbur, John Silke
10.7554/eLife.10592

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Show10255075100rows
Showing results 1 - 10 of 107