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Immunology

Immunology


The eLife journal publishes Immunology research including allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. eLife is a unique, non-profit, researcher-driven initiative. Editorial decisions are made exclusively by working scientists in your field.


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Showing results 1 - 10 of 62
The cytotoxicity exerted by CD8+ T cells against parasitized erythroblasts helps to protect against blood-stage malaria by making parasitized cells susceptible to phagocytosis.
Takashi Imai, Hidekazu Ishida, Kazutomo Suzue, Tomoyo Taniguchi, Hiroko Okada, Chikako Shimokawa, Hajime Hisaeda
10.7554/eLife.04232
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T cell receptor signaling is regulated by newly polymerized F-actin foci at the immunological synapse.
Sudha Kumari, David Depoil, Roberta Martinelli, Edward Judokusumo, Guillaume Carmona, Frank B Gertler, Lance C Kam, Christopher V Carman, Janis K Burkhardt, Darrell J Irvine, Michael L Dustin
10.7554/eLife.04953
A novel mouse model of immunization against Plasmodium chabaudi involving infectious mosquito bites and drug-treatment elicits protection against blood-stage malaria parasites, and shows that protection is not necessarily life cycle stage-specific.
Wiebke Nahrendorf, Philip J Spence, Irene Tumwine, Prisca Lévy, William Jarra, Robert W Sauerwein, Jean Langhorne
10.7554/eLife.05165
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HOIL-1 deficiency in mice results in a severe immunodeficiency that is effectively complemented by chronic infection with a murine gamma-herpesvirus.
Donna A MacDuff, Tiffany A Reese, Jacqueline M Kimmey, Leslie A Weiss, Christina Song, Xin Zhang, Amal Kambal, Erning Duan, Javier A Carrero, Bertrand Boisson, Emmanuel Laplantine, Alain Israel, Capucine Picard, Marco Colonna, Brian T Edelson, L David Sibley, Christina L Stallings, Jean-Laurent Casanova, Kazuhiro Iwai, Herbert W Virgin
10.7554/eLife.04494
Differentiation of CD4 T cells into CD4 T follicular helper cells during viral infection in mice is promoted by tumor growth factor beta.
Heather D Marshall, John P Ray, Brian J Laidlaw, Nianzhi Zhang, Dipika Gawande, Matthew M Staron, Joe Craft, Susan M Kaech
10.7554/eLife.04851
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Peptide immunotherapy in mice depends upon sustained expression of co-inhibitory protein PD-1 in T cells.
Rhoanne C McPherson, Joanne E Konkel, Catriona T Prendergast, John P Thomson, Raffaele Ottaviano, Melanie D Leech, Oliver Kay, Stephanie E J Zandee, Claire H Sweenie, David C Wraith, Richard R Meehan, Amanda J Drake, Stephen M Anderton
10.7554/eLife.03416
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Genetic susceptibility to an infectious disease is linked to competition for binding a molecule on the bacterial surface by two host proteins with opposing roles in host immunity.
Joseph JE Caesar, Hayley Lavender, Philip N Ward, Rachel M Exley, Jack Eaton, Emily Chittock, Talat H Malik, Elena Goiecoechea De Jorge, Matthew C Pickering, Christoph M Tang, Susan M Lea
10.7554/eLife.04008

Pages

Show10255075100rows
Showing results 1 - 10 of 62