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Immunology

Immunology

eLife publishes research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Decisions are made by journal editors who are active researchers in the field of immunology.

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Redundancy in the costimulatory signals that drive CD8+ T cell expansion is dictated by pathogen-specific cues.
Suzanne PM Welten, Anke Redeker, Kees LMC Franken, Jennifer D Oduro, Ferry Ossendorp, Luka Čičin-Šain, Cornelis JM Melief, Peter Aichele, Ramon Arens
10.7554/eLife.07486
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The B cell receptors of naïve B cells need higher levels of mechanical force to be fully activated than those of memory B cells.
Zhengpeng Wan, Xiangjun Chen, Haodong Chen, Qinghua Ji, Yingjia Chen, Jing Wang, Yiyun Cao, Fei Wang, Jizhong Lou, Zhuo Tang, Wanli Liu
10.7554/eLife.06925
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Temporal availability of antigen presentation by dendritic cells influences the differentiation of follicular helper T (Tfh) cells, which enhances germinal centre responses and induces protective immunity.
Robert A Benson, Megan KL MacLeod, Benjamin G Hale, Agapitos Patakas, Paul Garside, James M Brewer
10.7554/eLife.06994
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Proliferation and differentiation of CD8+ T cells into terminal effectors occurs in the marginal zone and red pulp, and is promoted by IL-12 through direct and indirect mechanisms.
Suhagi Shah, Gijsbert M Grotenbreg, Amariliz Rivera, George S Yap
10.7554/eLife.09017
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Pain sensation induces relapse in a mouse model of multiple sclerosis via a sensory-sympathetic signaling pathway.
Yasunobu Arima, Daisuke Kamimura, Toru Atsumi, Masaya Harada, Tadafumi Kawamoto, Naoki Nishikawa, Andrea Stofkova, Takuto Ohki, Kotaro Higuchi, Yuji Morimoto, Peter Wieghofer, Yuka Okada, Yuki Mori, Saburo Sakoda, Shizuya Saika, Yoshichika Yoshioka, Issei Komuro, Toshihide Yamashita, Toshio Hirano, Marco Prinz, Masaaki Murakami
10.7554/eLife.08733
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Pages

Show10255075100rows
Showing results 1 - 10 of 84