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Immunology

Immunology


The eLife journal publishes Immunology research including allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. eLife is a unique, non-profit, researcher-driven initiative. Editorial decisions are made exclusively by working scientists in your field.


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Accepted manuscript
Paul Chappell, El Kahina Meziane, Michael Harrison, Łukasz Magiera, Clemens Hermann, Laura Mears, Antony G Wrobel, Charlotte Durant, Lise Lotte Nielsen, Soren Buus, Nicola Ternette, William Mwangi, Colin Butter, Venugopal Nair, Trudy Ahyee, Richard Duggleby, Alejandro Madrigal, Pietro Roversi, Susan M Lea, Jim Kaufman
10.7554/eLife.05345
By contributing to the maintenance of ROS homeostasis, CD33-related Siglecs control oxidative damage and influence rate of aging and lifespan.
Flavio Schwarz, Oliver MT Pearce, Xiaoxia Wang, Annie N Samraj, Heinz Läubli, Javier O Garcia, Hongqiao Lin, Xiaoming Fu, Andrea Garcia-Bingman, Patrick Secrest, Casey E Romanoski, Charles Heyser, Christopher K Glass, Stanley L Hazen, Nissi Varki, Ajit Varki, Pascal Gagneux
10.7554/eLife.06184
The cytotoxicity exerted by CD8+ T cells against parasitized erythroblasts helps to protect against blood-stage malaria by making parasitized cells susceptible to phagocytosis.
Takashi Imai, Hidekazu Ishida, Kazutomo Suzue, Tomoyo Taniguchi, Hiroko Okada, Chikako Shimokawa, Hajime Hisaeda
10.7554/eLife.04232
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T cell receptor signaling is regulated by newly polymerized F-actin foci at the immunological synapse.
Sudha Kumari, David Depoil, Roberta Martinelli, Edward Judokusumo, Guillaume Carmona, Frank B Gertler, Lance C Kam, Christopher V Carman, Janis K Burkhardt, Darrell J Irvine, Michael L Dustin
10.7554/eLife.04953
A novel mouse model of immunization against Plasmodium chabaudi involving infectious mosquito bites and drug-treatment elicits protection against blood-stage malaria parasites, and shows that protection is not necessarily life cycle stage-specific.
Wiebke Nahrendorf, Philip J Spence, Irene Tumwine, Prisca Lévy, William Jarra, Robert W Sauerwein, Jean Langhorne
10.7554/eLife.05165
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HOIL-1 deficiency in mice results in a severe immunodeficiency that is effectively complemented by chronic infection with a murine gamma-herpesvirus.
Donna A MacDuff, Tiffany A Reese, Jacqueline M Kimmey, Leslie A Weiss, Christina Song, Xin Zhang, Amal Kambal, Erning Duan, Javier A Carrero, Bertrand Boisson, Emmanuel Laplantine, Alain Israel, Capucine Picard, Marco Colonna, Brian T Edelson, L David Sibley, Christina L Stallings, Jean-Laurent Casanova, Kazuhiro Iwai, Herbert W Virgin
10.7554/eLife.04494
Differentiation of CD4 T cells into CD4 T follicular helper cells during viral infection in mice is promoted by tumor growth factor beta.
Heather D Marshall, John P Ray, Brian J Laidlaw, Nianzhi Zhang, Dipika Gawande, Matthew M Staron, Joe Craft, Susan M Kaech
10.7554/eLife.04851
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Pages

Show10255075100rows
Showing results 1 - 10 of 64