Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
The electrogenic Na+/K+-ATPase generates a slow activity-dependent feedback signal that influences the computation of excitable cells and requires additional compensatory mechanisms during periods of high sustained activity.
Julia S Pinho, Carla Ramon-Duaso ... Arnau Busquets-Garcia
A light–tone sensory preconditioning task in male mice is developed revealing sex differences and demonstrating that dorsal, but not ventral, hippocampal CaMKII-positive neurons encode innocuous stimulus associations.
The Major Histocompatibility Complex region evolves via gene birth-and-death, resulting in short-lived genes, rapidly expanding gene subfamilies, and many gene fragments.
Eed, a core subunit of Polycomb repressive complex 2, is required for craniofacial osteoblast differentiation and mesenchymal proliferation after induction of the neural crest.
A normative computational model of individual differences in mouse exploration driven by reward and threat uncertainty as well as risk sensitivity when faced with a novel object in an open field.
Ramesh Chittajallu, Anna Vlachos ... Chris J McBain
A pharmacogenetic approach provides a foundational dataset describing the influence of opioids on synaptic processing in a brain microcircuit known to be critical for driving hedonic behaviors.
Samuel Bru, Lydie Michaillat Mayer ... Andreas Mayer
In vitro reconstitution identifies how lysosome-related vacuoles coordinate the synthesis and turnover of inorganic polyphosphates to create a powerful buffer system stabilising a vital metabolic parameter, the cytosolic concentration of phosphate.
Stephania Assimopoulos, Shaun Warrington ... Stamatios N Sotiropoulos
By providing new ways to map cortico-subcortical connectivity patterns, the proposed cross-species tractography approaches directly allow novel comparative studies between the human and macaque brain and enable subsequent explorations of brain-behaviour/disease symptom associations across individuals.
