Research Articles

Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.

Latest articles

    1. Developmental Biology

    Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye

    Alicia Hurtado, Victor López-Soriano ... Francisco Javier Barrionuevo
    The Sox9 gene is necessary for maintaining vision in the mouse adult eye, acting as an essential factor for retinal and corneal function.
    1. Neuroscience

    Mixed evidence for the rhythmicity of auditory perceptual judgements in humans

    Cécile Fabio, Christoph Kayser
    Across multiple experiments, the evidence for any rhythmicity of auditory perception remains difficult to establish.
    1. Evolutionary Biology

    Convergent iridescence and divergent chemical signals in sympatric sister-species of Amazonian butterflies

    Joséphine Ledamoisel, Bruno Buatois ... Violaine Llaurens
    Ecological interactions exert contrasting evolutionary pressures on sympatric Morpho butterflies, promoting convergence in iridescence but divergence in chemical cues, illustrating how ecological interactions mediate trait evolution and sister-species coexistence.
    1. Evolutionary Biology

    Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (Ooceraea biroi)

    Kip D Lacy, Jina Lee ... Daniel JC Kronauer
    A complementary sex determination locus is conserved in ants and dates back to approximately 112 million years ago.
    1. Immunology and Inflammation

    Layers of immunity: Deconstructing the Drosophila effector response

    Faustine Ryckebusch, Yao Tian ... Bruno Lemaitre
    New tools make it possible to investigate the timing and importance of different immune effectors in defense against infection.
    1. Neuroscience

    Recovery of the full in vivo firing range in post-lesion surviving DA SN neurons associated with Kv4.3-mediated pacemaker plasticity

    Lora Kovacheva, Josef Shin ... Jochen Roeper
    Dopamine midbrain neurons surviving a lesion slowly recover their in vivo firing patterns by homeostatic pacemaker acceleration mediated by Kv4.3 channel downregulation.
    1. Medicine

    Cell-autonomous and non-cell-autonomous effects of Arginase 2 on cardiac aging

    Duilio M Potenza, Xin Cheng ... Xiu-Fen Ming
    Arginase 2 in macrophages promotes cardiac aging phenotype via paracrine release of IL-1β.
    1. Computational and Systems Biology
    2. Neuroscience

    Correlation detection as a stimulus computable account for audiovisual perception, causal inference, and saliency maps in mammals

    Cesare V Parise
    Optimal cue integration, Bayesian Causal Inference, spatial orienting, speech illusions and other key phenomena in audiovisual perception naturally emerge from the collective behavior of a population of Multisensory Correlation Detector.
    1. Neuroscience

    Characterization of postsynaptic glutamate transporter functionality in the zebrafish retinal first synapse across different wavelengths

    Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
    Loss of the glutamate transporters EAAT5b and EAAT7 disrupts wavelength-specific visual processing and UV-dependent prey detection in zebrafish, revealing their key roles in modulating light integration and behaviorally relevant vision.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Characterization of binding kinetics and intracellular signaling of new psychoactive substances targeting cannabinoid receptor using transition-based reweighting method

    Soumajit Dutta, Diwakar Shukla
    New psychoactive substances activate cannabinoid receptors using distinct ligand-receptor interactions.
Load more