Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Dopamine midbrain neurons surviving a lesion slowly recover their in vivo firing patterns by homeostatic pacemaker acceleration mediated by Kv4.3 channel downregulation.
Optimal cue integration, Bayesian Causal Inference, spatial orienting, speech illusions and other key phenomena in audiovisual perception naturally emerge from the collective behavior of a population of Multisensory Correlation Detector.
Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
Loss of the glutamate transporters EAAT5b and EAAT7 disrupts wavelength-specific visual processing and UV-dependent prey detection in zebrafish, revealing their key roles in modulating light integration and behaviorally relevant vision.
Short heat shock factor variants prevent hyperactivation of thermotolerance through a noncanonical heat shock response, thereby balancing heat stress response and plant growth.
Sub-membrane microtubule array, known to prevent excessive glucose-stimulated insulin secretion, depends on kinesin-1 KIF5B, which moves microtubules to both generate and remodel this array, potentially regulating the dosage of secretion.
Ion channel voltage-dependence alterations can shape intrinsic homeostatic plasticity, even if operating faster than other intrinsic regulatory processes—where timescale separation would suggest its influence should be negligible.
Stefanie SM Meier, Michael Hörzing ... Andreas Möglich
Custom-tailored bathy-phytochromes control bacterial gene expression by near-infrared light while exhibiting minimal response to red light, thus unlocking innovative application scenarios.