Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Rats with a history of cocaine use exhibited prolonged encoding of idiosyncratic task features in orbitofrontal cortex and a reduced ability to compress such features to identify underlying hidden states.
Interactions between pairs of humans lead to the emergence of a dyadic vigor with similar characteristics as individual vigor, where both partners adapt, with the slower having a critical role.
Graph theory and computational modeling reveal that neural network architecture biases the male Caenorhabditis elegans brain toward prioritized sexual behaviors.
High‑resolution cryo‑EM structures uncover YbjP as a novel lipoprotein that positions TolC and supports conformational changes in E. coli drug efflux pumps mediating antibiotic resistance.
Zhimin Lao, Salsabiel El Nagar ... Alexandra L Joyner
Homozygous but not heterozygous loss of Pten in sporadic mouse models of SHH-medulloblastoma greatly accelerates tumor formation, not metastasis, through increased survival of differentiated cells and possibly decreased infiltrating macrophages.
Mammalian cells dynamically scale translation initiation to match distinct elongation rates, preventing ribosome crowding and preserving protein synthesis homeostasis across diverse transcripts.
Yuri Z Sinzato, Robert Uittenbogaard ... Maziyar Jalaal
Flow experiments show how the formation of cyanobacterial colonies is driven by cell division, aggregation, and fragmentation under different hydrodynamic conditions.
Modality-agnostic decoders leverage modality-invariant representations in human subjects' brain activity to predict stimuli irrespective of their modality (image, text, mental imagery).
