Stem Cells and Regenerative Medicine

Latest articles

1. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during mouse skeletal muscle regeneration

   Yue Lu, Tezin Walji ... Elizabeth H Chen

   Branched actin cytoskeleton is critical for myoblast fusion during mouse skeletal muscle regeneration.
2. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

   Abdulkadir Ozkan, Hari K Padmanabhan ... Jeffrey D Macklis

   Developmentally-based directed differentiation from cortical progenitors sets a foundation for in vitro mechanistic and therapeutic disease modeling, and toward regenerative neuronal repopulation and circuit repair.
3. 1. Medicine
   2. Stem Cells and Regenerative Medicine

   A titin missense variant drives atrial electrical remodeling and is associated with atrial fibrillation

   Mahmud Arif Pavel, Hanna Chen ... Dawood Darbar

   Genetic and electrophysiological studies uncover a mechanism linking a TTN missense variant to atrial fibrillation by coupling titin with potassium channel remodeling, revealing FHL2 as a modulator and therapeutic target.
4. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Efficient transduction of pancreas tissue slices with genetically encoded calcium integrators

   Charles S Lazimi, Austin E Stis ... Edward A Phelps
5. 1. Stem Cells and Regenerative Medicine

   Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of osteoarthritis

   Nedaa Al-Jezani, Asmaa Affan ... Roman J Krawetz

   CD47^Hi synovial mesenchymal stem cells are identified as a functionally distinct sub-population that regenerates articular cartilage and reduces osteoarthritis severity in a preclinical joint injury model.
6. 1. Immunology and Inflammation
   2. Stem Cells and Regenerative Medicine

   IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

   Daniel L Aldridge, Zachary Lanzar ... Christopher A Hunter

   Functional analyses showcase that in the absence of IL-27, hematopoietic stem and progenitor cells are more likely to become monocytes during toxoplasmosis, making them less responsive after infection.
7. 1. Stem Cells and Regenerative Medicine

   Glycogen engineering improves the starvation resistance of mesenchymal stem cells and their therapeutic efficacy in pulmonary fibrosis

   Yongyue Xu, Mamatali Rahman ... Qiong Wu

   Glycogen engineering strategies of mammalian cells were developed, which improved the survival of mesenchymal stem cells post-implantation and their therapeutic efficacy in pulmonary fibrosis model.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

   Justine Bajohr, Erica Y Scott ... Maryam Faiz
9. 1. Genetics and Genomics
   2. Stem Cells and Regenerative Medicine

   Joint profiling of cell morphology and gene expression during in vitro neurodevelopment

   Adithi Sundaresh, Dimitri Meistermann ... Helena Kilpinen

   Molecular and morphological profiles of developing neurons in vitro uncover the cellular dynamics of human neurodevelopment and related disease.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians

    Ryan A McCubbin, Mohammad A Auwal ... Ricardo M Zayas

    A conserved POU4-dependent developmental program underlies mechanosensory neuron regeneration in adult planarians.