Browse our latest Chromosomes and Gene Expression articles

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    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Epigenetics and chromatin structure regulate var2csa expression and the placental binding phenotype in Plasmodium falciparum

    Todd Lenz, Madle Sirel ... Ulf Ribacke
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

    Ananda Kishore Mukherjee, Subhajit Dutta ... Shantanu Chowdhury
    1. Chromosomes and Gene Expression

    Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors

    Miin S. Lin, Se-Young Jo ... Vineet Bafna
    1. Chromosomes and Gene Expression

    Control of meiotic entry by dual inhibition of a key mitotic transcription factor

    Amanda J Su, Siri C Yendluri, Elçin Ünal
    Investigation of how cells rewire their transcriptional programs during transition from mitotic to meiotic cell fate reveals a two-pronged mechanism for inactivating a key mitotic transcription factor.
    1. Chromosomes and Gene Expression

    DNA methylation-environment interactions in the human genome

    Rachel A Johnston, Katherine A Aracena ... Jenny Tung
    A massively parallel reporter assay, mSTARR-seq, reveals widespread DNA methylation-environment interactions across the genome, prioritizing CpG sites identified in epigenome-wide association studies that may be most relevant to biological embedding.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    A TOPBP1 allele causing male infertility uncouples XY silencing dynamics from sex body formation

    Carolline Ascenção, Jennie R Sims ... Marcus B Smolka
    A Topbp1 mutant mouse reveals a non-canonical role for the ATR-TOPBP1 signaling axis in meiosis, separating ATR signaling and meiotic sex chromosome inactivation from sex body formation.
    1. Chromosomes and Gene Expression

    Translation: It’s a competitive business

    Masaaki Sokabe, Christopher S Fraser
    A new in vitro system called Rec-Seq sheds light on how mRNA molecules compete for the machinery that translates their genetic sequence into proteins.
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    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of ZDBF2

    Hisato Kobayashi, Tatsushi Igaki ... Kazuki Kurimoto
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Nucleosome conformation dictates the histone code

    Matthew R Marunde, Harrison A Fuchs ... Catherine A Musselman
    NMR spectroscopy, dCypher assays, and CUT&RUN demonstrate that occlusion of the histone tails in the nucleosome context alters histone PTM specificity for a tandem of reader domains.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Tempo and mode of gene expression evolution in the brain across primates

    Katherine Rickelton, Trisha M Zintel ... Courtney C Babbitt
    Larger phylogenetic context is required to understand human and nonhuman primate brain evolution.
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