AlphaFold-Multimer was used to investigate extracellular protein interactions involved in mammalian egg-sperm recognition, suggesting a putative pentameric complex that includes TMEM81, a sperm protein not previously involved in gamete recognition.
Sensory hair cells in the inner ear use inhibitory G proteins with different regulators at different stages of development to break symmetry, adopt a proper orientation, and grow stereocilia.
Edgar M Pera, Josefine Nilsson-De Moura ... Ivana Milas
An extracellular proteolytic pathway involving the serine protease HtrA1, its inhibitor SerpinE2, and the transmembrane proteoglycan Syndecan-4 control collective migration of neural crest cells in the developing embryo.
Kristine B Walhovd, Stine K Krogsrud ... Didac Vidal-Pineiro
Greater early developmental growth, as indexed by birth weight, relates to greater cortical volume and area in a stable way through the human lifespan.