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Biochemistry

Biochemistry

eLife publishes research spanning chemical biology and enzymology to metabolism and membrane proteins. Decisions are made by journal editors who are active researchers in biochemistry.


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Structural and functional analyses show how the spliceosomal Prp3 protein concomitantly binds double- and single- stranded regions in U4/U6 di-snRNAs and serves to stabilize the U4/U6•U5 tri-snRNP for splicing.
Sunbin Liu, Sina Mozaffari-Jovin, Jan Wollenhaupt, Karine F Santos, Matthias Theuser, Stanislaw Dunin-Horkawicz, Patrizia Fabrizio, Janusz M Bujnicki, Reinhard Lührmann, Markus C Wahl
10.7554/eLife.07320
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