Biochemistry and Chemical Biology

Latest articles

1. 1. Biochemistry and Chemical Biology

   #GotGlycans: Role of N343 Glycosylation on the SARS-CoV-2 S RBD Structure and Co-Receptor Binding Across Variants of Concern

   Callum M. Ives, Linh Nguyen ... Elisa Fadda
2. 1. Biochemistry and Chemical Biology
   2. Evolutionary Biology

   A mitochondrial carrier transports glycolytic intermediates to link cytosolic and mitochondrial glycolysis in the human gut parasite Blastocystis

   Eva Pyrihová, Martin S King ... Edmund RS Kunji

   Stramenopiles are unusual, because the pay-off phase of glycolysis occurs in mitochondria rather than the cytosol and the identified mitochondrial carrier links the two parts by transporting glycolytic intermediates.
3. 1. Biochemistry and Chemical Biology

   Human pannexin 1 channel is not phosphorylated by Src tyrosine kinase at Tyr199 and Tyr309

   Zheng Ruan, Junuk Lee ... Wei Lü

   A comprehensive analysis questioned the prevailing views of Src-mediated hPANX1 phosphorylation at Tyr199 and Tyr309.
4. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Structural and dynamic changes in P-Rex1 upon activation by PIP₃ and inhibition by IP₄

   Sandeep K. Ravala, Sendi Rafael Adame-Garcia ... John J. G. Tesmer
5. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Heparan sulfate dependent phase separation of CCL5 and its chemotactic activity

   Xiaolin Yu, Guangfei Duan ... Shi-Zhong Luo
6. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Melanophilin mediates the association of myosin-5a with melanosome via three distinct interactions

   Jiabin Pan, Rui Zhou ... Xiang-dong Li
7. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Remodeling of skeletal muscle myosin metabolic states in hibernating mammals

   Christopher TA Lewis, Elise G Melhedegaard ... Julien Ochala

   During hibernation, animals remodel the structure of their relaxed muscle via a protein called myosin and this enables vast temperature changes.
8. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   Hyperglycemia-induced cathepsin L maturation: Linking to diabetic comorbidities and COVID-19 mortality

   Qiong He, Miao-Miao Zhao ... Jin-Kui Yang
9. 1. Biochemistry and Chemical Biology
   2. Neuroscience

   Deciphering the chemical language of inbred and wild mouse conspecific scents

   Maximilian Nagel, Marco Niestroj ... Marc Spehr

   Parallel chemical and physiological profiling of conspecific chemosensory communication in mice identifies both common and unique strategies for vomeronasal signaling of sex and strain.
10. 1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Caenorhabditis elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA

    Claudia D Consalvo, Adedeji M Aderounmu ... Brenda L Bass

    Biochemical and structural analyses unravel how two RIG-I-like helicases function together to promote antiviral defense and illustrates the diverse ways innate immunity evolved.