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Latest articles

1. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Cardiac Repair: Aiming for spatial and temporal control of gene expression

   Stanislao Igor Travisano, Ching-Ling Lien

   Bioluminescent imaging is helping researchers better understand the effectiveness of tissue regeneration enhancers delivered to injured heart tissue by different adeno-associated virus vectors.
2. 1. Cell Biology

   Senescence: Returning aging cells to productivity

   Rachana W Vaidya, Simon Y Tang

   Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.
3. 1. Immunology and Inflammation

   Acute Lung Injury: The double-edged nature of trained immunity

   Chrissy M Leopold Wager, Larry S Schlesinger

   Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.
4. 1. Biochemistry and Chemical Biology

   RNA: Searching for druggable targets

   Lana Heganovic, Luiz FM Passalacqua

   A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.
5. 1. Computational and Systems Biology

   Methylation: Modifying gene expression through passive forces

   Sarah Hallstein, Julian König

   The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
6. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Cancer: Reading the DNA of telomeres

   Shamayita Roy, Claus M Azzalin

   Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.
7. 1. Medicine

   Aging: Multiple roles for a mitochondrial enzyme

   Xicong Tang, Hongyu Qiu

   The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.
8. 1. Neuroscience

   Touch: A lasting impression

   Rochelle Ackerley, Roger H Watkins

   Touch-sensitive neurons in the fingertips take previous physical contacts into account when relaying tactile information to the brain.
9. 1. Neuroscience

   Neurodevelopmental Disorders: Unraveling the impact of genetic variants

   Bruce Herring

   Experiments in mice reveal how three rare mutations in a gene called TRIO can lead to different neurodevelopmental outcomes.
10. 1. Immunology and Inflammation

    Interferon Signaling: Immobilizing bacteria to prevent infections

    Patricia Reist Iscar, Petr Broz

    The interferon-induced GTPase GVIN1 prevents bacteria from spreading among cells by coating them and rendering them immobile.