Browse the latest research

18,522 results found
    1. Neuroscience

    Motor unit mechanisms of speed control in mouse locomotion

    Kyle Thomas, Rhuna Gibbs ... Samuel J Sober
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    A geometric shape regularity effect in the human brain

    Mathias Sablé-Meyer, Lucas Benjamin ... Stanislas Dehaene
    fMRI and MEG results in adults and children show encoding of abstract geometric regularities in dorsal-parietal, temporal, and frontal regions, pointing to a system for symbolic geometric representation in humans.
    1. Physics of Living Systems

    Linking complex microbial interactions and dysbiosis through a disordered Lotka–Volterra model

    Jacopo Pasqualini, Amos Maritan ... Samir Suweis
    Linking biological research with disordered-systems modeling, providing new insights into gut microbiome stability, functioning, and their relationship with health.
    1. Cell Biology

    Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance

    Atsushi Matsumoto, Akihito Inoko ... Junichi Ikenouchi
    Lipid imbalance triggered by Snail-driven epithelial–mesenchymal transition creates a cholesterol-dependent vulnerability that can be therapeutically targeted to overcome chemoresistance in cancer.
    1. Cell Biology
    2. Neuroscience

    Dilated cardiomyopathy-associated RNA-binding motif protein 20 regulates long pre-mRNAs in neurons

    Giulia Di Bartolomei, Raúl Ortiz ... Peter Scheiffele
    An alternative splicing regulator previously implicated in calcium signaling in the heart ensures cell-type-specific mRNA processing of long neuronal mRNAs in the mouse brain.
    1. Computational and Systems Biology

    Predicting the effect of CRISPR-Cas9-based epigenome editing

    Sanjit Singh Batra, Alan Cabrera ... Yun S Song
    Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based epigenome editing.
    1. Cell Biology

    Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

    J Ignacio Gutierrez, Claudia Edgar, Jessica K Tyler
    Live imaging analyses in budding yeast reveal that calorie restriction and overexpression of the mRNA binding protein Ssd1 both block deleterious age-dependent iron uptake as a mechanism to extend lifespan.
    1. Physics of Living Systems

    Division Asymmetry Drives Cell Size Variability in Budding Yeast

    Félix Proulx-Giraldeau, Xin Gao ... Paul Francois
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Mouse sensorimotor cortex reflects complex kinematic details during reaching and grasping

    Harrison A Grier, Sohrab Salimian, Matthew T Kaufman
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Physics of Living Systems

    Interplay Between Pulmonary Membrane Properties and Lung Disease: A Study of Seven Bottlenose Dolphins

    Marilyn Porras-Gómez, Bengu Sueda Sengul ... Cecília Leal
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete

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