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Conventional colony counting obscures bacterial population structure by conflating biological heterogeneity with stochastic noise from dilution and plating, which can be separated by explicitly modeling the measurement process.

VBIT-4 perturbs lipid membranes without detectably affecting VDAC1 channels or oligomerization, calling for careful interpretation of its biological effects and highlighting the need to assess membrane interactions of hydrophobic compounds.

A desolvation-aware coarse-grained framework enables efficient and physically realistic modeling of biomolecular phase separation by capturing water-mediated effects on phase behavior, dense-phase packing, conformational reorganization, and dynamics.

Spatial clustering of mutations in Mycobacterium tuberculosis proteins finds proteins that are involved in antibiotic resistance, and predicts which mutations cause resistance.