Browse our latest research

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    1. Neuroscience

    Distinct cell-type contributions and network topography of theta-nested gamma oscillations in the medial entorhinal cortex

    Brandon Williams, Riya Dahal ... John A White
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    Germline-somatic residue synergy reshapes antibody encounter-state pathways to enhance HIV-1 recognition

    Sangita Kachhap, Yishak Bililign ... Rory Henderson
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Chromosomes and Gene Expression
    2. Medicine

    Gene dosage imbalance disrupts systemic metabolism in the Dp16 Down syndrome mouse model

    Fangluo Chen, Muzna Saqib ... G William Wong
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Structural Biology and Molecular Biophysics

    A stable cryogenic fluorescence microscope for correlative super-resolution light and electron microscopy

    Soheil Mojiri, Joseph M Dobbs ... Jonas Ries
    Not revised
    Reviewed Preprint v1
    • Useful
    • Compelling
    1. Structural Biology and Molecular Biophysics

    Structural basis for site-specific histone H3 acetylation-dependent regulation of RNAPII transcription through nucleosomes

    Takumi Oishi, Suguru Hatazawa ... Hitoshi Kurumizaka
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

    Kexin Qi, Yuming Chai ... Quan Wen
    Serotonin promotes a sleep-independent quiescent state through selective modulation of motor neural population dynamics.
    1. Neuroscience

    The view tolerance of human identity recognition depends on horizontal face information

    Alexia Roux-Sibilon, Helene Dumont ... Valerie Goffaux
    View-tolerant identity recognition in humans depends on the stable identity cues provided by horizontal facial information.
    1. Neuroscience

    Organization of circuits linking descending input to motor output in the Drosophila Male Adult Nerve Cord connectome

    Han SJ Cheong, Katharina Eichler ... Gwyneth M Card
    Circuit analyses of synaptic connectivity in networks connecting descending and motor neurons in the Drosophila Male Adult Nerve Cord connectome reveal the modular network organization of descending to motor pathways.
    1. Developmental Biology
    2. Genetics and Genomics

    Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells

    Volker Soltys, Moritz A Peters ... Yingguang Frank Chan
    A single-cell multiomic technique measuring both transcription and chromatin accessibility in the same cell.
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    Cluster size determines internal structure of transcription factories in human cells

    Massimiliano Semeraro, Giuseppe Negro ... Davide Marenduzzo
    In a polymer model of chromatin that explicitly incorporates different types of transcription factors, both specialised and mixed factories emerge naturally, with their composition governed by their size.