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    1. Structural Biology and Molecular Biophysics

    Multi-barrier unfolding of the double-knotted protein, TrmD–Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

    Fernando Bruno da Silva, Szymon Niewieczerzal ... Joanna I Sulkowska
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Medicine

    Gender differences in submission behavior exacerbate publication disparities in elite journals

    Chaoqun Ni, Isabel Basson ... Vincent Larivière
    Gender differences in submission behavior, driven by self-perceptions of novelty and peer discouragement, limit women’s representation in high-impact journals and, in turn, their scientific visibility and career advancement.
    1. Cell Biology

    Abnormal shear stress induces ferroptosis in endothelial cells via KLF6 downregulation

    Jingang Cui, Zhiyu Fan ... Yongsheng Ding
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Neuroscience

    PSD-95 drives binocular vision maturation critical for predation

    Subhodeep Bhattacharya, Livia JF Wilod Versprille ... Siegrid Löwel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Inadequate
    1. Biochemistry and Chemical Biology

    Cul5Wsb2 uses BCL2 proteins as co-receptors to target Bim for degradation

    Wilhelm Vaysse-Zinkhöfer, Enya Marie Catherine Alcindor ... David Paul Toczyski
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Synaptotagmin-7 is required for synchronous but not asynchronous facilitation of glutamate release at cortical boutons

    Dimitris Kotzadimitriou, Helen Langley ... Kirill E Volynski
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    A novel RAB5 binding site in human VPS34-CII that is likely the primordial site in eukaryotic evolution

    Saulė Špokaitė, Yohei Ohashi ... Roger L Williams
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Transition of Staphylococcus aureus tetracycline resistance plasmid pT181 from independent multicopy replicon to predominantly integrated chromosomal element over 65 years

    Megan A Phillips, Robert A Petit ... Timothy D Read
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Dynamic regulation of mRNA acetylation at synapses by spatial memory in mouse hippocampus

    Hai-Qian Zhou, Zhen Zhu ... Dong-Min Yin
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Medicine
    2. Neuroscience

    Juvenile reinstatement of TCF4 in Pitt-Hopkins syndrome model mice reveals a critical window for genetic intervention

    Lucas M James, Carlee A Friar ... Benjamin D Philpot
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
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