Browse our latest research

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    1. Neuroscience

    Tunable Bessel beam two-photon fluorescence microscopy for high-speed volumetric imaging of brain dynamics

    Mengyang Jacky Li, Jinghui Wang ... Tian-Ming Fu
    Tunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and volume coverage, allowing flexible sampling and measurements of vascular, neuronal, and immune dynamics.
    1. Neuroscience

    Material damage to multielectrode arrays after electrolytic lesioning is insignificant

    Alice Tor, Stephen E Clarke ... Paul Nuyujukian
    An analysis of the largest publicly available collection of scanning electron microscopy images of explanted multielectrode arrays reveals that electrolytic lesioning causes no significant additional damage to array electrodes.
    1. Immunology and Inflammation

    Metabolic support of trained immune responses in myeloid cells

    Aitor Jarit-Cabanillas, Gillian Dunphy ... David Sancho
    A review of literature regarding trained immunity (TI) differentiates two distinct stages of metabolic immune regulation, with primary metabolic changes influencing early epigenetic adaptations that drive TI induction and secondary metabolic adaptations providing building blocks required for enhanced immune function.
    1. Immunology and Inflammation

    Simplifying principles that underlie the highly complex peptide motif of the promiscuous chicken class I molecule, BF2*21:01

    Michael Harrison, Paul E Chappell ... Jim Kaufman
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Virus specific impacts on honey bee flight performance are mediated by the octopamine pathway

    Naomi G Kaku, Michelle L Flenniken
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Genetics and Genomics

    The cistrome response to hypoxia in human umbilical vein endothelial cells

    Ayush Singh, Viktor Pastukh ... Hank W Bass
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Evolutionary Biology

    Species biology and demographic history determine species vulnerability to climate change in tropical island endemic birds

    Ratnesh Karjee, Vikram Iyer ... Balaji Chattopadhyay
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Inadequate
    1. Neuroscience

    Visual Working Memory Guides Attention Rhythmically

    Jiachen Lu, Yaochun Cai, Xilin Zhang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Synaptotagmin isoforms differentially regulate glutamate and GABA release in the lateral habenula

    Dustin N White, J Keenan Kushner ... Michael HB Stowell
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Celldetective: an AI-enhanced image analysis tool for unraveling dynamic cell interactions

    Rémy Torro, Beatriz Díaz-Bello ... Laurent Limozin
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing