A combination of three transcriptional regulators (CEBPB, NFE2L2, and BCL3) can shift macrophages from an M1 to an M2 phenotype, altering their susceptibility to bacterial infection.
The glycolipid MPIase acts as a receptor of twin-arginine translocation (TAT) signals, inserts them into membranes, and potentially modulates the TatABC structure to facilitate TAT translocation.
Infectious disease resistance in chickens strongly depends on a genomic region called the MHC, and the rules governing pathogen peptide presentation for a key MHC molecule may aid vaccine development.
Yi Lueningschroer-Wang, Emilia Derksen ... Christian Wegener
Wall-following and total walking activity in a behavioural assay can serve as indicators of emotional valence and arousal and provide evidence for the presence of emotion primitives in fruit flies.
The choice of fitness metric is crucial in microbial ecology—commonly chosen metrics lead to different results that may affect the conclusions from pairwise competition assays and high-throughput genetic screens.
