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    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    MORC2 Mediates Transcriptional Regulation Through Liquid-Liquid Phase Separation

    Yanshen Zhang, Weiya Xu ... Yihui Bi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Method of loci training yields unique prefrontal representations that support effective memory encoding

    Jingyuan Ren, Boris N Konrad ... Isabella C Wagner
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology

    Differential Regulation of Hepatic Macrophage Fate by Chi3l1 in MASLD

    Jia He, Bo Chen ... Zhao Shan
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Solid
    1. Evolutionary Biology

    Inference of germinal center evolutionary dynamics via simulation-based deep learning

    Duncan K Ralph, Athanasios G Bakis ... Frederick A Matsen
    Deep learning applied to B cell phylogenies reveals a simple, measurable curve relating receptor affinity to evolutionary fitness in germinal centers.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Interrogating the structure and function of the human voltage-gated proton channel (hHv1) with a fluorescent noncanonical amino acid

    Emerson M Carmona, William N Zagotta, Sharona E Gordon
    A fluorescent noncanonical amino acid enables structural measurements across full-length human voltage-gated proton channel (Hv1) and reveals zinc-dependent conformational changes.
    1. Evolutionary Biology

    Are interphylum spiralian relationships resolvable?

    Ana Serra Silva, Maximilian J Telford
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Immunology and Inflammation

    GM-CSF regulates ILC states and myeloid cell signaling during ulceration in Crohn’s disease

    Joshua K Morrison, Ksenija Sabic ... Ling-shiang Chuang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Circadian control of a sex-specific behaviour in Drosophila

    Sabrina Riva, M Fernanda Ceriani ... D Lorena Franco
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    Revised
    Reviewed Preprint v2
    Updated
    • Landmark
    • Exceptional
    1. Medicine
    2. Neuroscience

    A non-human primate model of Amyotrophic Lateral Sclerosis

    Rachael HA Jones, Luciano Saieva ... Stuart N Baker
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
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