MOTS-c, a mitochondrial-encoded microprotein, has immunological origins and functions, revealing for the first time that our immune system is encoded by both co-evolved nuclear and mitochondrial genomes.
In a mouse model of E. coli meningitis, non-myeloid TLR4 signaling is a key determinant of the inflammatory response in all leptomeningeal cells and of the increase in vascular permeability.
Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
Latent developmental potential facilitates trait re-evolution with novel phenotypic patterns, adding a new perspective to understanding of the origins of novel traits in evolutionary and developmental biology.
Ali Özgür Argunşah, Tevye Jason Stachniak ... Theofanis Karayannis
Elfn1-mediated synaptic facilitation onto somatostatin-positive interneurons drives the local lateral inhibition required to functionally segregate cortical barrel and septal processing domains in mice.
