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    1. Immunology and Inflammation

    Gelsolin Counteracts ER Stress-Driven Inflammatory Circuits in Psoriasis-like Dermatitis

    Daisuke Ori, Haruna Okude ... Taro Kawai
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Compensation of Hyperexcitability with Simulation-Based Inference

    Daniel Müller-Komorowska, Tomoki Fukai
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in Drosophila

    Dongni Shao Chen, Jin Man ... Yuu Kimata
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    Temperature-based MHC class-I multimer peptide exchange for human HLA-A, B and C

    Cilia R Pothast, Ian Derksen ... Ferenc A Scheeren
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Genome-wide synthetic lethality screen of Bam complex-associated genes in Escherichia coli

    Jack A Bryant, Kara A Staunton ... Manuel Banzhaf
    High-throughput genetics reveals all synthetic-lethal relationships for outer membrane protein biogenesis associated genes in Escherichia coli.
    1. Neuroscience

    Circadian photoreceptor CRYPTOCHROME promotes wakefulness under short winter-like days via a GABAergic circuitry

    Lixia Chen, Danya Tian ... Luoying Zhang
    The circadian photoreceptor CRYPTOCHROME selectively inhibits sleep under short winter day length by tuning down GABAergic tone within pacemaker neuron network.
    1. Cell Biology

    Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism

    Fangqing Deng, Rong Yang ... Lianbing Zhang
    Periodic red-light irradiation promotes coupling between keratinocyte mitochondrial lipid metabolism and epigenetic remodeling, increasing acetyl-CoA availability and histone H3 lysine 9 acetylation to slow skin aging.
    1. Genetics and Genomics

    A pleiotropic EPAS1 enhancer mediating Tibetan adaptation to hypoxia is active in adipocytes

    Alexis G Thornburg, Soo-Young Park ... Marcelo A Nóbrega
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    An integrated human forebrain organoid reveals microglia-mediated CD8⁺ T cell recruitment and neuroimmune dysfunction in Alzheimer’s disease pathology

    Yilin Feng, Feifei Yu ... Shaohua Ma
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Complementary stable and dynamic prelimbic ensembles encode learned threat value underlying generalization and discrimination

    Marc E Normandin, Pedro M Ogallar ... Isabel A Muzzio
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
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