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    1. Structural Biology and Molecular Biophysics

    Insights into substrate binding and utilization by hyaluronan synthase

    Zachery Stephens, Julia Karasinska, Jochen Zimmer
    Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.
    1. Neuroscience

    Spatially targeted inhibitory rhythms differentially affect neuronal integration

    Drew B Headley, Benjamin Latimer ... Satish S Nair
    Beta and gamma inhibitory rhythms are preferentially tuned to govern synaptic integration in layer 5 pyramidal neurons by differentially modulating responses to inputs targeting distal dendritic and perisomatic compartments.
    1. Neuroscience

    Readout and delayed transmission of initial afferent V1 activity in decisions about stimulus contrast

    Kieran S Mohr, Simon P Kelly
    Evidence is provided suggesting that aggregate neural activity at an early stage of visual processing (V1) can directly contribute to perceptual decisions in humans.
    1. Developmental Biology
    2. Genetics and Genomics

    Ripply1 and Gsc collectively suppress anterior endoderm differentiation from prechordal plate progenitors

    Tao Cheng, Xiang Liu ... Peng-Fei Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to Plasmodium infection

    Kely C Matteucci, Nathalia PS Leite ... Ricardo T Gazzinelli
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Rescuing the Function of Missense-Mutated Tumor Suppressor VHL using Stabilizing Small Molecules

    Mariam Ahmed Fouad, Christopher S Parry ... John Karanicolas
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Immunology and Inflammation

    Temporal single-cell analysis reveals age-associated delay in immune resolution after respiratory viral infection

    Yue Wu, Chaofan Li ... Jie Sun
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Neural Representation of Time across Complementary Reference Frames

    Yangwen Xu, Nicola Sartorato ... Roberto Bottini
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Immunology and Inflammation

    HEB collaborates with TCR signaling to upregulate Id3 and enable γδT17 cell maturation in the fetal thymus

    Johanna S Selvaratnam, Juliana Dutra Barbosa da Rocha ... Michele K Anderson
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    Dual Inhibition of MYRF Cleavage by Its JM Region and PAN-1 CCT Gates Developmental Timing in C. elegans

    Zhimin Xu, Xiaoting Feng ... Yingchuan B Qi
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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