Browse our latest research

Page 2 of 1,807
    1. Cancer Biology

    Mitochondrial Protein Carboxyl-Terminal Alanine-Threonine Tailing Promotes Glioblastoma Tumor Growth by Regulating Mitochondrial Function

    Bei Zhang, Ting Cai ... Zhihao Wu
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    State-dependent brain responsiveness, from local circuits to the whole brain

    Alain Destexhe, Jennifer S Goldman ... Maria V Sanchez-Vives
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Causal evidence for a domain-specific role of left superior frontal sulcus in human perceptual decision making

    Miguel Barretto García, Marcus Grueschow ... Christian C Ruff
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    The impact of different antimicrobial exposures on the gut microbiome in the ARMORD observational study

    Leon Peto, Nicola Fawcett ... Ann Sarah Walker
    Metagenomic sequencing of stool samples from 225 hospital patients and healthy volunteers reveals the impact of different antimicrobial exposures on the gut microbiome.
    1. Medicine

    Addressing cultural and knowledge barriers to enable preclinical sex inclusive research

    Brianna N Gaskill, Benjamin Phillips ... Natasha A Karp
    Targeted education corrects key misconceptions and identifies methods to influence intent to use sex-inclusive designs in in vivo studies.
    1. Cell Biology

    Evidence of centromeric histone 3 chaperone involved in DNA damage repair pathway in budding yeast

    Prakhar Agarwal, Anushka Alekar ... Santanu K Ghosh
    Genetic and biochemical assays reveal the role of Scm3 in genome stability by regulating the DNA damage checkpoint pathway in budding yeast.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Dock-and-lock binding of SxIP ligands is required for stable and selective EB1 interactions

    Teresa Almeida, Eleanor Hargreaves ... Igor Barsukov
    Structural analysis reveals a two-step EB1-SxIP binding mechanism and identifies ligand mutations that greatly enhance affinity, offering potential therapeutic avenues for targeting microtubule plus end interactions.
    1. Neuroscience

    Longitudinal tracking of neuronal activity from the same cells in the developing brain using Track2p

    Jure Majnik, Manon Mantez ... Rosa Cossart
    A novel algorithm allowed for the continuous tracking of neurons throughout early postnatal development, revealing a transition in neural firing statistics coinciding with the onset of behaviour-dependent activity.
    1. Neuroscience

    How Occam’s razor guides human decision-making

    Eugenio Piasini, Shuze Liu ... Joshua I Gold
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

    Shuang Chen, Andrew R Mack ... Shozeb Haider
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete