Browse our latest research

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    1. Cancer Biology

    PCNA-Polκ-Polδ/USP18 axes stabilize replication fork and restart to reduce cisplatin cytotoxicity

    Ipsita Subhadarsini, Jugal Kishor Sahu ... Narottam Acharya
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Cooperative antibiotic response in coupled biofilm and planktonic E. faecalis communities

    Gabriela Fernandes Martins, Keanu Alexander Guardiola-Flores ... Kevin Wood
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Anterior cingulate cortex monitors action state and action content in complex associative learning

    Wenqiang Huang, Arron F Hall ... Dong V Wang
    ACC contains specialized neurons that sustain rich action-relevant information after action execution, enabling prolonged action monitoring, and supporting complex associative linking across events.
    1. Chromosomes and Gene Expression

    Cell-cycle-resolved Hi-C reveals unexpected plasticity of A/B compartments across interphase

    Linda Choubani, Hisashi Miura ... Ichiro Hiratani
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    The cell cycle variant in multiciliated cells incorporates 2 centriole biogenesis cycles

    Amélie-Rose Boudjema, Rémi Balagué ... Alice Meunier
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Characterization of an early-diverging KCNE potassium-channel auxiliary subunit in the jawless vertebrate lamprey

    Go Kasuya, Kaei Ryu ... Koichi Nakajo
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Yoda molecules agonize PIEZO2

    Tharaka D Wijerathne, Aneesh Chandrasekharan ... Jérôme J Lacroix
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Comparing the outputs of intramural and extramural grants funded by National Institutes of Health

    Xiang Zheng, Qiyao Yang ... B Ian Hutchins
    Funding mechanisms impact the cost effectiveness of the science conducted, as extramural NIH grants to universities excel at producing papers and citations, while intramural NIH hiring more effectively translates to clinical impact.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Inferring variant-specific effective reproduction numbers from combined case and sequencing data

    Marlin D Figgins, Trevor Bedford
    Integrating case counts with genomic sequences quantifies real-time transmission advantages of viral variants.
    1. Neuroscience

    How attention simplifies mental representations for planning

    Jason da Silva Castanheira, Christina Chang He ... Stephen M Fleming
    Spatial attention controls the information people become aware of and, in turn, incorporate into simplified perceptual representations for use in multi-step planning.