Browse our latest research

Page 2 of 1,808
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis

    Naphannop Sereesongsaeng, Carole Bataille ... Terence Rabbitts
    Antibody surrogate degraders of LMO2 indicate that transcription complexes are susceptible to drug discovery and are therefore druggable.
    1. Cancer Biology

    Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics

    Inbal Avraham-Davidi, Simon Mages ... Aviv Regev
    An integrative analysis of scRNA-seq and spatial transcriptomics provides complementary views into the biology of pre-clinical colorectal cancer models in mice with possible applications to the human system.
    1. Neuroscience

    Separating the control of moving and holding in human post-stroke arm paresis

    Alkis M Hadjiosif, Kahori Kita ... John W Krakauer
    Patients with stroke often show impairment in both moving and holding the arm, deficits that are dissociable experimentally, suggesting that moving and holding are controlled by separate neural mechanisms.
    1. Neuroscience

    Sex-specific exploration accounts for differences in valence learning in male and female mice

    Heike Schuler, Eshaan S Iyer ... Rosemary C Bagot
    1. Neuroscience

    Virtual Brain Inference (VBI), a flexible and integrative toolkit for efficient probabilistic inference on whole-brain models

    Abolfazl Ziaeemehr, Marmaduke Woodman ... Meysam Hashemi
    The Virtual Brain Inference (VBI) toolkit enables efficient, accurate, and scalable Bayesian inference over whole-brain network models, improving parameter estimation, uncertainty quantification, and predictive modeling across neuroimaging modalities toward precision medicine.
    1. Ecology

    Range geography and temperature variability explain cross-continental convergence in range and phenology shifts in a model insect taxon

    Catherine Sirois-Delisle, Susan CC Gordon, Jeremy Kerr
    Across continents, half of odonate species shifted both ranges and phenologies in response to climate warming, with southern species and those experiencing less temperature variability shifting ranges more strongly.
    1. Neuroscience

    Information, certainty, and learning

    Justin A Harris, Charles R Gallistel
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Epidemiology and Global Health

    Estimating probabilities of malaria importation in southern Mozambique through P. falciparum genomics and mobility patterns

    Arnau Pujol, Arlindo Chidimatembue ... Alfredo Mayor
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

    Roberta Carloni, Tadhg Devlin ... Robin C Allshire
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology

    THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle

    Taylar Hammond, Jong Bin Choi ... Julien Sage
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid