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Page 2 of 1,851
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Lineage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors

    William Salvidge, Chris Brimson ... Chris Thompson
    Experiments and mathematical modelling show cell fate in Dictyostelium discoideum partly depends on cell-cycle phase, but also on stochastic gene-expression variability which enhances robustness of developmental responses to cell-cycle perturbation.
    1. Chromosomes and Gene Expression

    Single-domain antibody inhibitors target the coiled coil arms of the Bacillus subtilis SMC complex

    Ophélie J Gosselin, Michael Taschner ... Stephan Gruber
    A screen using in vitro-selected synthetic nanobodies identified inhibitors of SMC protein function in bacterial cells, revealing a coiled coil region as a vital component of the chromosome-folding machinery.
    Version of Record
    Research Article
    • Important
    • Compelling
    • Convincing
    1. Ecology

    Full factorial construction of synthetic microbial communities

    Juan Diaz-Colunga, Pablo Catalan ... Alvaro Sanchez
    A rapid, inexpensive, and easy to implement experimental protocol enables the construction of combinatorially complete sets of microbial consortia.
    1. Cell Biology

    Cell surface localisation of GPI-anchored receptors in Trypanosoma brucei

    Sourav Banerjee, Nicola Minshall ... Mark Carrington
    The glycosylphosphatidylinositol (GPI)-anchored receptors in Trypanosoma brucei are not confined to the flagellar pocket but instead localise across the whole cell surface, reshaping our understanding of host immune evasion and nutrient uptake.
    1. Neuroscience

    Understanding neural circuit principles for representation learning through joint-embedding predictive architectures

    Ashena Gorgan Mohammadi, Manu Srinath Halvagal, Friedemann Zenke
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Neuroscience

    Acute opioid responses are modulated by dynamic interactions of Oprm1 and Fgf12

    Paige M Lemen, Yanning Zuo ... Hao Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Frequency-dependent modulation of foveal contrast sensitivity by fine-scale exogenously triggered attention

    Yue Guzhang, T Florian Jaeger, Martina Poletti
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Physics of Living Systems

    Anatomy and mechanics of tsetse fly blood feeding

    Stephan Löwe, Laura Hauf ... Markus Engstler
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization

    Roland Philipp, Yuki Hara ... Kazuhiko Seki
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked release

    Javier Emperador-Melero, Steven J Del Signore ... Avital A Rodal
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling