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    1. Genetics and Genomics

    The cistrome response to hypoxia in human umbilical vein endothelial cells

    Ayush Singh, Viktor Pastukh ... Hank W Bass
    The genomic response of endothelial cells to hypoxia via MOA-seq transcription factor occupancy profiling identified known and novel HIF1A-associated and independent cis-regulatory elements, which defined ten distinct hypoxic kinetic clusters.
    1. Neuroscience

    Brainstem neurons coordinate the bladder and urethral sphincter for urination

    Xing Li, Xianping Li ... Jiwei Yao
    Estrogen receptor 1 (ESR1)-positive neurons in the pontine micturition center govern detrusor–sphincter coordination via three distinct spinal projections, representing a therapeutic target for detrusor–sphincter dyssynergia and associated voiding dysfunction.
    1. Microbiology and Infectious Disease

    Pathogen-phage geomapping to overcome resistance

    Camilla Do, Keiko Christine Salazar ... Anthony W Maresso
    Targeted ecological sampling combined with a portable enrichment device rapidly yields a diverse array of bacteriophages against drug-resistant pathogens.
    1. Cancer Biology

    Heterotypic interfacial tension between oncogenic and wild-type populations forms the mechanical basis of tissue-specific oncogenesis in epithelia

    Amrapali Datta, Phanindra Dewan ... Medhavi Vishwakarma
    Mechanical interactions at the interface of mutant and wild-type cell populations govern tissue-specific responses to oncogenic transformation in epithelia, causing mutants to be extruded, spatially restrained, or undergo persistent expansion.
    1. Neuroscience

    An integrated human forebrain organoid reveals microglia-mediated CD8+ T cell recruitment and neuroimmune dysfunction in Alzheimer’s disease pathology

    Yilin Feng, Feifei Yu ... Shaohua Ma
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Cancer Biology

    Slap restricts oncogenic Src-family kinase signaling to maintain colonic epithelial homeostasis

    Dana Naim, Zouheir Houhou ... Serge Roche
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Simple Methods to Acutely Measure Multiple Timing Metrics among Sexual Repertoire of Male Drosophila

    Yutong Song, Hongyu Miao ... Woo Jae Kim
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Neuroscience

    Economic and Social Modulations of Innate Decision-Making in Mice Exposed to Visual Threats

    Zhe Li, Jiahui Wang ... Ya-tang Li
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Distinct neural representations of perceptual and numerical absence in the human brain

    Benjy Barnett, Stephen M Fleming
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model

    Po-Kai Wang, Keng-Hui Lin, Tang K Tang
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
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