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    1. Computational and Systems Biology

    Predicting dynamic expression patterns in budding yeast with a fungal DNA language model

    Kuan-Hao Chao, Majed Mohamed Magzoub ... David R Kelley
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cancer Biology

    An Itch Receptor Drives Melanoma

    Naina Gour, Aishwarya Atakkatan ... Xinzhong Dong
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Ecology

    Novel but stable endosymbionts have contrasting effects on aphid dispersal and plant feeding damage in the cereal pest Diuraphis noxia

    Xinyue Gu, Alex Gill ... Ary A Hoffmann
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    Bidirectional redistribution of actomyosin drives epithelial invagination in ascidian siphon tube morphogenesis

    Jinghan Qiao, Pengyu Yu ... Bo Dong
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Rank- and threat-dependent social modulation of innate defensive behaviors

    Ling-yun Li, Xinjian Gao ... Ya-tang Li
    Social context modulates innate defensive behaviors in a rank- and threat-dependent manner, while threat experience reinforces social roles, revealing a bidirectional interplay between defensive and social behavior.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Computational and Systems Biology

    Comprehensive RNA velocity by modeling the cascade of gene regulation, transcription, and splicing from single-cell RNA sequencing data with TSvelo

    Jiachen Li, Zhe Wang ... Ye Yuan
    TSvelo provides a comprehensive RNA velocity mathematics framework that can model the cascade of gene regulation, transcription, and splicing.
    1. Microbiology and Infectious Disease
    2. Computational and Systems Biology

    A new diagnostic modality for bovine tuberculosis: accurate and robust classification of infected cattle using transcriptomics and machine learning

    John F O’Grady, Adriana Ivich ... David E MacHugh
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    A predictive systems vaccinology framework enables rational optimization of MVA-based vaccines

    Vincent Deman, Philippe Castera ... Anne-Sophie Beignon
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Persistent Microglial HIV Infection Drives Neuroinflammation Despite Viral Suppression: Insights from Rapid Postmortem Brain Biopsies

    M Nühn Marieke, Nadia Sabet ... Jori Symons
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Ectopic hAMH-driven SOX17 expression induces hyperplastic Sertoli valve formation in mouse testes

    Xiao Han, Aya Uchida ... Yoshiakira Kanai
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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