Highlights

  • Context-dependent behavior

    A region of the brain called the retrosplenial cortex has an important role in integrating contextual information and sensory stimuli in mice.

    Pol Bech, Robin F Dard ... Carl CH Petersen
    Reviewed Preprint Updated

  • Seeing movement

    Inhibitory feedback from GABAergic interneurons C2 and C3 is tied to neural computation of moving visual stimuli in Drosophila.

    Miriam Henning, Madhura D Ketkar ... Marion Silies
    Research Article

  • Testing the blood-brain barrier

    pdgfrb knockout zebrafish, which lack mural cells in their neurovasculature, retain restrictive permeability of the blood-brain barrier during developmental stages.

    Oguzhan F Baltaci, Andrea Usseglio Gaudi ... Benjamin M Hogan
    Research Article

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article

  • How to respond to peer reviewers

    Responding to peer reviews is a crucial part of publishing, but early-career researchers are rarely taught about it.

    Eric Kalkhoven, Manon Kluijtmans
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    Human decision-makers terminate evidence accumulation using flexible decision rules

    Ishan Kalburge, Alice Dallstream ... Joshua I Gold
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    More than just a passive brick in the wall: the nucleosome facilitates DNA polymerase β activity in linker DNA and its PARP-dependent regulation in the BER pathway choice

    Danil M Shtanov, Tatyana A Kurgina ... Olga I Lavrik
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Glutamate receptor composition at Drosophila neuromuscular junctions depends on developmental stage and muscle identity

    Anne Sustar, Chengjie Qiu ... John C Tuthill
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Canonical and phosphoribosyl ubiquitination coordinate to stabilize a proteinaceous structure surrounding the Legionella-containing vacuole

    Adriana Steinbach, Chetan Mokkapati ... Shaeri Mukherjee
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Noncanonical amino acid incorporation enables minimally disruptive labeling of stress granule and TDP-43 proteinopathy

    Hao Chen, Haocheng Wang ... Jiou Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Neuroscience

    Hippocampal representations differentiate reactive and anticipatory responses during foraging under threat

    Chelsey C Damphousse, Olivia L Calvin, A David Redish
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Dual-feature selectivity enables bidirectional coding in visual cortical neurons

    Nikos Karantzas, Katrin Franke ... Andreas Tolias
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Structural Biology and Molecular Biophysics

    Myristoylation licenses disordered viral VP4 protein to anchor to and perforate the membrane through phase separation

    Sichao Huang, Fengzhen Deng ... Bin Sun
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Exposure to false cardiac feedback alters pain perception and anticipatory cardiac frequency

    Eleonora Parrotta, Patric Bach ... Francesca Ferri
    Interoceptive predictions can bias both the subjective experience of pain and physiological preparation.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma

    Ariunaa Bayanjargal, Cenny Taslim ... Emily Rose Theisen
    A discrete helix in the fusion oncoprotein DNA binding domain shifts binding preferences toward long and dense GGAA repeats, which promotes transcriptional hub formation and drives EWSR1::FLI1-mediated gene regulation.
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Magazine

    1. Neuroscience

    Hippocampal Network: Stronger memories through smarter stimulation

    Justin Riddle
    1. Neuroscience

    Verbal Memory: Language acquisition in newborns

    Marcela Peña

  3. Episode 103: May 2026

    1. Neuroscience

    Visual Perception: Insights into perceptual learning

    Zhong-Lin Lu
    1. Neuroscience

    Neuroendocrinology: Surging towards a better understanding of ovulation

    Lillian Rose, Alexander S Kauffman
    1. Cell Biology
    2. Neuroscience

    Auditory Hair Cells: Examining the role of lipids in hearing

    Yein Christina Park, Angela Ballesteros

  7. Point of View: Science under threat around the world

    Humberto J Debat
  8. See more Magazine articles

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