Highlights

  • Seeing movement

    Inhibitory feedback from GABAergic interneurons C2 and C3 is tied to neural computation of moving visual stimuli in Drosophila.

    Miriam Henning, Madhura D Ketkar ... Marion Silies
    Research Article

  • Testing the blood-brain barrier

    pdgfrb knockout zebrafish, which lack mural cells in their neurovasculature, retain restrictive permeability of the blood-brain barrier during developmental stages.

    Oguzhan F Baltaci, Andrea Usseglio Gaudi ... Benjamin M Hogan
    Research Article

  • Making of the microenvironment

    Single-cell sequencing and multi-omics approaches reveal the influence of BRCA1/2 mutations on the tumor microenvironment in lung adenocarcinoma.

    Gaoming Liao, Xinbin Yang ... Gang Xu
    Research Article

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article

  • How to respond to peer reviewers

    Responding to peer reviews is a crucial part of publishing, but early-career researchers are rarely taught about it.

    Eric Kalkhoven, Manon Kluijtmans
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Cell Biology
    2. Neuroscience

    BetaII-Spectrin Gaps and Patches Emerge from the Patterned Assembly of the Actin/Spectrin Membrane Skeleton in Human Motor Neuron Axons

    Nahir Guadalupe Gazal, Maria Jose Castellanos-Montiel ... Nicolás Unsain
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Cell-to-cell signalling mediated via CO2: activity dependent axonal CO2 production opens Cx32 in the Schwann cell paranode

    Jack Butler, Lowell Mott ... Nicholas Dale
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to Plasmodium infection

    Kely C Matteucci, Nathalia PS Leite ... Ricardo T Gazzinelli
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Neuroscience

    Differential locus coeruleus–hippocampus interactions during offline states

    Mingyu Yang, Oxana Eschenko
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Optimising the tilt-increment for in situ cryo-electron tomography

    Maarten W Tuijtel, Tomáš Majtner ... Martin Beck
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure

    Elvi Gil-Lievana, Benjamin Arroyo ... Ranier Gutierrez
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells

    Volker Soltys, Moritz Peters ... Yingguang Frank Chan
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Epidemiology and Global Health

    Heterogeneity of use, access and retention of insecticide-treated nets: implications for subnational tailoring to maximise malaria control

    Andrew C Glover, Hannah Koenker ... Thomas S Churcher
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Esr1-dependent signaling and transcriptional maturation in the medial preoptic area of the hypothalamus shape the development of mating behavior during adolescence

    Koichi Hashikawa, Yoshiko Hashikawa ... Garret D Stuber
    Esr1 directs adolescent transcriptional maturation of medial preoptic GABAergic neurons, enabling the normal development of mating behavior in male and female mice.
    1. Neuroscience

    Tunable Bessel beam two-photon fluorescence microscopy for high-speed volumetric imaging of brain dynamics

    Mengyang Jacky Li, Jinghui Wang ... Tian-Ming Fu
    Tunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and volume coverage, allowing flexible sampling and measurements of vascular, neuronal, and immune dynamics.
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Magazine

    1. Neuroscience

    Hippocampal Network: Stronger memories through smarter stimulation

    Justin Riddle
    1. Neuroscience

    Verbal Memory: Language acquisition in newborns

    Marcela Peña

  3. Episode 103: May 2026

    1. Neuroscience

    Visual Perception: Insights into perceptual learning

    Zhong-Lin Lu
    1. Neuroscience

    Neuroendocrinology: Surging towards a better understanding of ovulation

    Lillian Rose, Alexander S Kauffman
    1. Cell Biology
    2. Neuroscience

    Auditory Hair Cells: Examining the role of lipids in hearing

    Yein Christina Park, Angela Ballesteros

  7. Point of View: Science under threat around the world

    Humberto J Debat
  8. See more Magazine articles

Categories

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  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
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  19. Structural Biology and Molecular Biophysics
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