Highlights

  • Bruce-mediated growth control

    Genetic, proteomic, and structural modelling techniques highlight the role of the protein Bruce in restraining Drosophila wing growth.

    Natsuki Shinoda, Yutaro Hama ... Masayuki Miura
    Research Article
  • Replication in Drosophila studies

    An analysis of 400 articles on the immune response in Drosophila highlights a need for caution regarding the replicability of certain claims.

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Reviewed Preprint Updated
  • Tsetse fly feeding adaptations

    Investigations into the biomechanics of tsetse fly blood feeding reveal that subtle anatomical adaptations enable the penetration of a diverse range of host hides.

    Stephan Löwe, Laura Hauf ... Markus Engstler
    Research Article
  • Neurosecretory connections

    Connectomic and transcriptomic analyses reveal the anatomical and functional organisation of neurosecretion in the Drosophila brain.

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Research Article
  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife
  • Explore our new collection

    Delve into leading research on Lifestyle, Environment and Epigenetic Inheritance.

    Collection

Latest research

    1. Neuroscience

    Number, order and time influence how the brain integrates distinct experiences

    Alina B Thomas, Francesca S Wong ... Nathan M Holmes
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    The psychedelic DOI decreases the modularity of the cortical network by increasing cortico-cortical and thalamo-cortical functional influence

    Roman Doronin, Eduard Stroukov, Georg B Keller
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Context makes the difference: Temporally Resolved Dopaminergic Teaching Signals Shape Associative Memory in Drosophila Larvae

    Denise Weber, Anna-Maria Jürgensen ... Andreas S Thum
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Neuroscience

    Correlative light–electron microscopy reveals fundamentally different axonal architectures for fast and modulatory transmission

    Kok-Sin Lee, Daniela A Sahlender ... Graham W Knott
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Ecology

    Extinction risk in terrestrial vertebrates is associated with niche limits that reflect climatic vulnerability

    Matthew Nagy-Watson, Jeremy T Kerr
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Computational and Systems Biology
    2. Cancer Biology

    Heterogeneous, population-level drug-tolerant persisters exhibit ion-channel remodeling and ferroptosis susceptibility

    Corey E Hayford, Blake Baleami ... Leonard A Harris
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Human mitochondrial DNA variants influence telomere length: evidence from a transmitochondrial cybrid model

    Manon Mahieu, Jean-Philippe Defour ... Anabelle Decottignies
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Endocardial TIE1 synergizes with TIE2 to regulate the atrial internal muscular network assembly

    Kai Ding, Beibei Xu ... Yulong He
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Intersection of transient cell states with stable cell types in hippocampus

    Jack A Olmstead, Lauren E King, Brenda L Bloodgood
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves learned motor execution

    Thawann Malfatti, Anna Velica ... Klas Kullander
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Compelling