Highlights

  • The evolution of effectors

    Pathogens that cause abnormal growths called galls in plants rely on effector molecules with structures and targeting strategies that are conserved across evolutionary lineages.

    Soham Mukhopadhyay, Muhammad Asim Javed ... Edel Perez-Lopez
    Tools and Resources

  • Modelling archaeal membranes

    Archaea use single-headed and double-headed lipids to construct cell membranes that are both flexible and capable of withstanding extreme environments.

    Miguel Amaral, Felix Frey ... Anđela Šarić
    Research Article

  • No change for astroctyes

    Genetically removing the RNA-binding protein PTBP1 from astrocytes does not convert them into neurons, contrary to previous claims.

    Min Zhang, Naoto Kubota ... Sika Zheng
    Reviewed Preprint Updated

  • Genetic pathways in brown algae

    Life-cycle-related patterns of gene expression are conserved across the brown algae.

    Pélagie Ratchinski, Olivier Godfroy ... J Mark Cock
    Reviewed Preprint Updated

  • Tracing cell fates in embryos

    Differences in the activity of an enzyme called CARM1 influence whether blastomeres become part of the embryo or the placenta.

    Ying Zhang, Qi Chen
    Insight

  • New university partnerships

    eLife is partnering with two leading UK universities on open access agreements that promote a more open and equitable approach to scientific publishing.

    Press Pack
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Cell Biology

    SMC5/6-Mediated Plasmid Silencing is Directed by SIMC1-SLF2 and Antagonized by the SV40 Large T Antigen

    Martina Oravcová, Minghua Nie ... Michael N Boddy
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Cell cycle-dependent cues regulate temporal patterning of the Drosophila central brain neural stem cells

    Gonzalo N Morales Chaya, Mubarak Hussain Syed
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Genetics and Genomics
    2. Ecology

    Microbial consortia in salt marsh sediments are sequentially buried over millennia and genomic complementarity analysis indicates an important role in complex carbon decomposition

    Joseph H Vineis, Ashley N Bulseco ... Jennifer L Bowen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Motor biases reflect a misalignment between visual and proprioceptive reference frames

    Tianhe Wang, Ryan J Morehead ... Jonathan S Tsay
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Enhanced Processivity and Collective Force Production of Kinesins at Low Radial Forces

    Andrew M Hensley, Ahmet Yildiz
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Formation of Task Representations and Replay in Mouse Medial Prefrontal Cortex

    Hamed Shabani, Hannah Muysers ... Christian Leibold
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Neuroscience

    Cross-modal interaction of Alpha Activity does not reflect inhibition of early sensory processing: A frequency tagging study using EEG and MEG

    Marion Brickwedde, Rupali Limachya ... Ali Mazaheri
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Roles of the membrane-binding motif and the C-terminal domain of RNase E in localization and diffusion in E. coli

    Laura Troyer, Yu-Huan Wang ... Sangjin Kim
    Single-molecule imaging uncovers how distinct membrane-binding motifs and the intrinsically disordered C-terminal domain control RNase E’s membrane association and diffusion, linking structural divergence to RNA-processing dynamics in bacteria.
    1. Neuroscience

    Rhythmic sampling and competition of target and distractor in a motion detection task

    Changhao Xiong, Nathan M Petro ... Mingzhou Ding
    Spatially and temporally overlapping target and distractor are both rhythmically sampled at ~1 Hz, and the phase relationship between target sampling and distractor sampling predicts behavior.
    1. Neuroscience

    Glaucoma-associated Optineurin mutations increase transcellular degradation of mitochondria in a vertebrate optic nerve

    Yaeram Jeong, Chung-ha O Davis ... Nicholas Marsh-Armstrong
    Increased transfer of axonal mitochondria to optic nerve astrocytes after expression of glaucoma-associated Optineurin variants suggest that increased transcellular degradation of axonal mitochondria may play a causative role in at least some forms of glaucoma.
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Magazine

    1. Medicine
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    3. Microbiology and Infectious Disease

    Focus Issue: Trained Immunity

    Edited by Satyajit Rath et al.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Focus Issue: Evolving our understanding of trained immunity

    Eva Kaufmann, Yahya Sohrabi ... Jos WM van der Meer
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Bacteriology: How Shigella tackles host defences

    Yizhou Huang, Teresa LM Thurston
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Chromosomes: Exploring a crossroads in the aging process

    Kiyan Shabestary, Daniel E Gottschling
    1. Neuroscience

    Neuronal Migration: How hunger guides new brain cells to their destination

    Fang-Shin Nian, Laurent Nguyen
    1. Neuroscience

    Primate Research: Probing the staying power of chemogenetics

    Maria Puchik, Igor Kagan
    1. Genetics and Genomics
    2. Neuroscience

    Aging: Unlocking the longevity code with stress

    Loren Cocciolone, Valeria Uvarova, Patricija van Oosten-Hawle
  8. See more Magazine articles

Categories

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