Highlights

  • T-cells target TB-infected cells

    Complementary human in vitro systems suggest a non-classical T-cell pathway contributing to immunity against Mycobacterium tuberculosis infection

    Matthew Milton, Sahar H Farag ... Salah Mansour
    Reviewed Preprint Updated

  • Mapping Regulatory DNA

    Cis-regulatory elements in the large genome of Parhyale hawaiensis can be identified by integrating chromatin accessibility and sequence conservation data.

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Reviewed Preprint Updated

  • Hypoxia to healthspan

    Genetic tools highlight potential signalling components underlying hypoxia-induced longevity in C. elegans.

    Elizabeth S Kitto, Shijiao Huang ... Scott F Leiser
    Reviewed Preprint Updated

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Microbiology and Infectious Disease

    Lactylation of Influenza Virus Polymerase Acidic Protein Promotes Viral Replication and Pathogenicity

    Shaoyu Tu, Yue Du ... Hongbo Zhou
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Bifunctional architecture enables substrate catalysis and channeling in Paracoccus TMAO demethylase

    Trung Thach, KanagaVijayan Dhanabalan ... Ramaswamy Subramanian
    Trimethylamine N-oxide demethylase uses substrate channeling to couple trimethylamine N-oxide demethylation with one-carbon metabolism, safely detoxifying formaldehyde while enhancing metabolic efficiency.
    1. Neuroscience

    Selective lifelong suppression of an odor processing channel in response to critical period experience

    Hans C Leier, Julius Jonaitis ... Andrew M Dacks
    Utilizing the olfactory system of Drosophila, a critical period paradigm has provided new insight into the selectivity and longevity of the impact of early life experiences on sensory system circuitry.
    1. Medicine
    2. Neuroscience

    Reverse engineering of motor unit discharge in multiple sclerosis reveals heterogeneity of voluntary motor commands

    Laura M McPherson, Keith R Lohse ... Anne H Cross
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cancer Biology

    IL1β/IL1R1/IRAK4 Drives Inflammatory Ovarian Cancer Seeding at the inflamed sites and Is Reversed by an IRAK4 inhibitor UR241-2

    John P Miller, Kyu Kwang Kim ... Rakesh K Singh
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology
    2. Immunology and Inflammation

    Digest before Ingest: Early Recruitment of Membrane-bound DNaseX to Phagocytic Cups in Macrophages

    Arghajit Pyne, Vivek Pandey ... Xuefeng Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Evolutionary Biology

    Evolutionary dynamics of insect odorant receptors reveal ecological tuning shaping olfactory perception

    Tianmin Zhang, Xuanxiao Yang ... Huimeng Lu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Medicine
    2. Neuroscience

    Synthetic torpor in the rat protects the heart from ischaemia-reperfusion injury

    Megan Elley, Ludovico Taddei ... Michael Ambler
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Physiology

    Ion channels and GPCR requirements for pressure-induced lymphatic chronotropy: Evidence for a Gαq/11-IP3R1-ANO1 pacemaking axis

    Michael J Davis, Hae Jin Kim ... Scott D Zawieja
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Genetics and Genomics
    2. Ecology

    Decomposition potential and population structure among active microbial communities in deep salt marsh sediments

    Joseph H Vineis, Ashley N Bulseco ... Jennifer L Bowen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
Load more

Magazine

  1. Close-up of an iris

    Episode 105: September 2026

    1. Cell Biology
    2. Computational and Systems Biology

    Philosophy of Biology: The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    1. Genetics and Genomics

    Environmental Learning: How experience shapes individuality

    Bassem A Hassan

  4. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
    1. Cell Biology

    Stress: How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Epidemiology and Global Health

    Malaria Prevention: Using mathematical models to optimise mosquito net distribution

    Carlos A Prete Jr
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
  17. Plant Biology
  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
Back to top