Highlights

  • Symbionts shape pest traits

    Novel endosymbiotic bacteria have contrasting effects on the performance and dispersal of Russian wheat aphids and on the severity of damage caused to cereal host plants.

    Xinyue Gu, Alex Gill ... Ary A Hoffmann
    Reviewed Preprint Updated

  • Neurosecretory connections

    Connectomic and transcriptomic analyses reveal the anatomical and functional organisation of neurosecretion in the Drosophila brain.

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Research Article

  • Replication in Drosophila studies

    An analysis of 400 articles on the immune response in Drosophila highlights a need for caution regarding the replicability of certain claims.

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Reviewed Preprint Updated

  • Hypoxia to healthspan

    Genetic tools highlight potential signalling components underlying hypoxia-induced longevity in C. elegans.

    Elizabeth S Kitto, Shijiao Huang ... Scott F Leiser
    Reviewed Preprint Updated

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Explore our new collection

    Delve into leading research on Lifestyle, Environment and Epigenetic Inheritance.

    Collection
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Genetics and Genomics
    2. Evolutionary Biology

    Phylogenomics of free-living neobodonids reveals they are a paraphyletic group from which all other metakinetoplastids are descended

    Daryna Zavadska, Julia A Packer ... Daniel J Richter
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Intracellular growth of Chlamydia trachomatis leads to global histone hypermethylation by impairing demethylation

    Chloé I Charendoff, Félix V Louchez ... Agathe Subtil
    The metabolic pressure exerted by a pathogen with an intracellular lifestyle drives epigenetic modifications, which modulate the transcriptional response of the host to infection.
    1. Physics of Living Systems

    Salmonids elicit an acute behavioral response to heterothermal environments

    Robert Naudascher, Stefano Brizzolara ... Roman Stocker
    Juvenile brown trout rapidly respond to fine-scale temperature disturbances, demonstrating behavioral mechanisms that support resilience to sudden thermal disruptions in freshwater ecosystems.
    1. Biochemistry and Chemical Biology

    NUDT2 loss defines quantitative limits for dinucleoside polyphosphate action on the cGAS–STING–TBK1 axis

    Paul Weiland, Renuka Dharani Shivakumar ... Gert Bange
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Glycolipid MPIase is essential for the TAT (Twin-Arginine Translocation) pathway

    Hanako Nishikawa, Nachi Yamamoto ... Ken-ichi Nishiyama
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Solid
    1. Physics of Living Systems

    Mechanics and fate stochasticity shape stem cell distribution in tissues

    Johannes C Krämer, Edouard Hannezo, Jens Elgeti
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Immunology and Inflammation

    Macrophages drive inguinal fat pad and lymph node remodelling in response to peripheral inflammation

    Robin Bartolini, Deepika Sharma ... Gerard J Graham
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

    Jennifer Kosmatka, Cong Liu ... Amy E Keating
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience
    2. Physiology

    Fitness Level, but not Sex, affects Exercise-Induced Pain Modulation

    Janne I Nold, Tahmine Fadai ... Christian Büchel
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Striatal dopamine and serotonin release operate largely in parallel with limited, asymmetric crosstalk

    Fabrice Chaudun, Yu Liu ... Christian Lüscher
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Convincing
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Magazine

    1. Computational and Systems Biology

    AI in Science: The 42 problem in AI-assisted research

    Giovanni Spitale, Federico Germani
    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan

  3. Research Culture: From East to West – an early-career researcher’s voyage across continents

    Samuel C Eziuzor
  4. Close-up of an iris

    Episode 105: September 2026

    1. Cell Biology
    2. Computational and Systems Biology

    Philosophy of Biology: The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    1. Genetics and Genomics

    Environmental Learning: How experience shapes individuality

    Bassem A Hassan

  7. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
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  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
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  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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