Highlights

  • Closing the neural tube

    High-throughput arrayed CRISPR interference screening of organoid models gives insight into genetic regulators of neural tube closure in humans.

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    Research Article

  • Mechanics of oncogenesis

    Integrative mechanobiological approaches provide insight into the biophysics of tissue-specific tumor growth.

    Amrapali Datta, Phanindra Dewan ... Medhavi Vishwakarma
    Research Article

  • Pikas power yak pastures

    Plateau pikas play a role in enhancing weight gains in yaks, by suppressing toxic plants and improving the availability and quality of palatable forage.

    Zhiwei Zhong, Bingbo Ni ... Zhibin Zhang
    Reviewed Preprint Updated

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Genetics and Genomics
    2. Evolutionary Biology

    Genome-wide architecture of prolonged starvation adaptation in experimentally evolved Drosophila and comparative enrichment in human orthologs

    Gaurav Yadav, Prachi Mishra ... Dau Dayal Aggarwal
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Acyl Carrier Protein is Essential for Apicoplast Biogenesis in Malaria Parasites Independent of Fatty Acid Synthesis

    Sage WR Geher, Seyi Falekun ... Paul A Sigala
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics
    2. Ecology

    Eco-genomic analysis uncovers precision-conservation targets for the western Pacific’s southernmost salmonid

    Yi-Chien Lee, Zong-Yu Shen ... Sheng-Feng Shen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Primordial cardiomyocytes orchestrate myocardial morphogenesis and vascularization but are dispensable for regeneration

    Jisheng Sun, Lu Chen, Jinhu Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    PRRT2 as an auxiliary regulator of Nav channel slow inactivation

    Bin Lu, Qi-Wu Xu ... Zhi-Qi Xiong
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Developmental Biology
    2. Genetics and Genomics

    Multiple molecular pathways to longevity with opposing gene expression programs defining distinct aging strategies in Caenorhabditis elegans

    Zenith D Rudich, Jiaxi Guan ... Jeremy M Van Raamsdonk
    Comparing gene expression across a panel of nine long-lived mutants in a single study reveals that these mutants utilize both common and unique genetic strategies to achieve long life.
    1. Neuroscience

    Neural computations in the foveal and peripheral visual fields during active search

    Jie Zhang, Xiaocang Zhu ... Huihui Zhou
    Foveal attentional processing coordinates with peripheral attention to dynamically shape global attention allocation and fixation behavior during active vision.
    1. Computational and Systems Biology

    Thymic selection of the T cell receptor repertoire is biased toward autoimmunity in females

    Hélène Vantomme, Valentin Quiniou ... David Klatzmann
    Sex-specific biases in thymic T cell receptor selection enrich female CD8 T cell repertoires for autoimmunity-associated self-antigens, helping explain women’s increased susceptibility to autoimmune diseases.
    1. Neuroscience

    Visuomotor mismatch EEG responses over occipital cortex of freely moving human subjects

    Magdalena Solyga, Marek Zelechowski, Georg B Keller
    Visuomotor mismatch events elicit robust human prediction error responses that exceed conventional oddball mismatch negativity, enabling translation of sensorimotor prediction mechanisms from mice to humans.
    1. Epidemiology and Global Health

    Heterogeneity of use, access, and retention of insecticide-treated nets: Implications for subnational tailoring to maximise malaria control

    Andrew C Glover, Hannah Koenker ... Thomas S Churcher
    While transmission intensity should still drive where insecticide-treated nets are prioritised, deprioritising areas where people are more likely to use nets may cause larger case resurgences than otherwise expected.
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Magazine

  1. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
    1. Cell Biology

    Stress: How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Epidemiology and Global Health

    Malaria Prevention: Using mathematical models to optimise mosquito net distribution

    Carlos A Prete Jr
    1. Plant Biology

    Mixotrophy: An updated view of glucose pathways in cyanobacteria

    José Manuel García-Fernández
  6. Mountain gorilla

    Episode 104: July 2026

    1. Cell Biology
    2. Developmental Biology

    Organ Development: Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois
  8. See more Magazine articles

Categories

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