Highlights

  • Complex connections

    Optogenetics reveals that interactions between the basal ganglia and the pedunculopontine nucleus (PPN), a region that has a central role in motor control, are more complex than previously thought.

    Michel Fallah, Kenea C Udobi ... Rebekah C Evans
    Research Article
  • The benefits of disorder

    The presence of an intrinsically disordered region in a transcription factor enhances both target binding and search efficiency.

    Wencheng Ji, Ori Hachmo ... Ariel Amir
    Reviewed Preprint Updated
  • Early influences on cell fate

    Cells that polarize early during the 8-cell stage of development in mouse embryos are more likely to become part of the placenta.

    Adiyant Lamba, Meng Zhu ... Magdalena Zernicka-Goetz
    Reviewed Preprint Updated

Latest research

    1. Physics of Living Systems

    The cytoplasm of living cells can sustain transient and steady intracellular pressure gradients

    Majid Malboubi, Mohammad Hadi Esteki ... Guillaume Charras
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Dual-format attentional template during preparation in human visual cortex

    Yilin Chen, Taosheng Liu ... Mengyuan Gong
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Neuroscience
    2. Ecology

    Individual recognition in a jumping spider (Phidippus regius)

    Christoph D Dahl, Yaling Cheng
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Incomplete
    1. Evolutionary Biology

    The holocephalan ratfish endoskeleton shares trabecular and areolar mineralization patterns, but not tesserae, with elasmobranchs little skate and catshark

    Oghenevwogaga J Atake, Fidji Berio ... B Frank Eames
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Structural Biology and Molecular Biophysics

    Allosteric effects of the coupling cation in melibiose transporter MelB

    Parameswaran Hariharan, Yuqi Shi ... Lan Guan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Ecology

    Range geography and temperature variability explain cross-continental convergence in range and phenology shifts in a model insect taxon

    Catherine Sirois-Delisle, Susan CC Gordon, Jeremy T Kerr
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Regional heterogeneities of oligodendrocytes underlie biased Ranvier node spacing along single axons in sound localization circuit

    Ryo Egawa, Kota Hiraga ... Hiroshi Kuba
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Mechanism of SK2 channel gating and its modulation by the bee toxin apamin and small molecules

    Samantha J Cassell, Weiyan Li ... Jonathan R Whicher
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Multimodal MRI Marker of Cognition Explains the Association Between Cognition and Mental Health in UK Biobank

    Irina Buianova, Mateus Silvestrin ... Narun Pat
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Physics of Living Systems

    Salmonids elicit an acute behavioral response to heterothermal environments

    Robert Naudascher, Stefano Brizzolara ... Roman Stocker
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid