Highlights

  • Re-evolving traits

    Hybridization chain reaction and confocal imaging reveal latent ocelli gene regulatory network expression in ant workers, with a role in partial re-evolution of caste-specific traits.

    Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
    Research Article

  • Body size and urban survival

    A global study of 30,000 species reveals how body size affects whether wildlife thrives or struggles in cities.

    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
    Research Article

  • T-cells target TB-infected cells

    Complementary human in vitro systems suggest a non-classical T-cell pathway contributing to immunity against Mycobacterium tuberculosis infection

    Matthew Milton, Sahar H Farag ... Salah Mansour
    Reviewed Preprint Updated

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    Rank- and threat-dependent social modulation of innate defensive behaviors

    Ling-yun Li, Xinjian Gao ... Ya-tang Li
    Social context modulates innate defensive behaviors in a rank- and threat-dependent manner, while threat experience reinforces social roles, revealing a bidirectional interplay between defensive and social behavior.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Computational and Systems Biology

    Comprehensive RNA velocity by modeling the cascade of gene regulation, transcription, and splicing from single-cell RNA sequencing data with TSvelo

    Jiachen Li, Zhe Wang ... Ye Yuan
    TSvelo provides a comprehensive RNA velocity mathematics framework that can model the cascade of gene regulation, transcription, and splicing.
    1. Microbiology and Infectious Disease
    2. Computational and Systems Biology

    A new diagnostic modality for bovine tuberculosis: accurate and robust classification of infected cattle using transcriptomics and machine learning

    John F O’Grady, Adriana Ivich ... David E MacHugh
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    A predictive systems vaccinology framework enables rational optimization of MVA-based vaccines

    Vincent Deman, Philippe Castera ... Anne-Sophie Beignon
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Persistent Microglial HIV Infection Drives Neuroinflammation Despite Viral Suppression: Insights from Rapid Postmortem Brain Biopsies

    M Nühn Marieke, Nadia Sabet ... Jori Symons
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Ectopic hAMH-driven SOX17 expression induces hyperplastic Sertoli valve formation in mouse testes

    Xiao Han, Aya Uchida ... Yoshiakira Kanai
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Galectin and Myc enable cochlear progenitor expansion in vitro and in vivo

    Marie Kubota, Julia M Abitbol ... Stefan Heller
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Morphology and ultrastructure of pharyngeal sense organs of Drosophila larvae

    Vincent Richter, Tilman Triphan ... Andreas S Thum
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Exceptional
    1. Physics of Living Systems

    Differential spatial regulation and activation of integrin nanoclusters inside focal adhesions

    Sarah Keary, Amaris Guevara-Garcia ... Maria F Garcia-Parajo
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Physics of Living Systems

    Sarcomere dynamic instability and stochastic heterogeneity drive robust cardiomyocyte contraction

    Daniel Haertter, Lara Hauke ... Christoph F Schmidt
    A non-monotonic force–velocity relationship in cardiac sarcomeres causes dynamic instability, leading to stochastic heterogeneity in contracting cardiomyocytes, which can have a protective function.
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Magazine

    1. Genetics and Genomics

    Environmental Learning: How experience shapes individuality

    Bassem A Hassan

  2. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
    1. Cell Biology

    Stress: How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Epidemiology and Global Health

    Malaria Prevention: Using mathematical models to optimise mosquito net distribution

    Carlos A Prete Jr
    1. Plant Biology

    Mixotrophy: An updated view of glucose pathways in cyanobacteria

    José Manuel García-Fernández
  7. Mountain gorilla

    Episode 104: July 2026

  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
  17. Plant Biology
  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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