Linking iron metabolism and metastasis in breast cancer

Latest research

1. 1. Ecology
   2. Physics of Living Systems

   Evidence of social learning across symbolic cultural barriers in sperm whales

   Antonio Leitao, Maxime Lucas ... Giovanni Petri
2. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors

   Damien M Rasmussen, Manny M Semonis ... Nicholas M Levinson

   A comprehensive allosteric model describes how inhibitors can activate rather than inhibit a target kinase by selectively driving formation of kinase dimers with one inhibited and one activated subunit.
3. 1. Computational and Systems Biology

   Phantasus, a web-application for visual and interactive gene expression analysis

   Maksim Kleverov, Daria Zenkova ... Alexey A Sergushichev
4. 1. Neuroscience

   Neuron-specific RNA-sequencing reveals different responses in peripheral neurons after nerve injury

   Sara Bolívar, Elisenda Sanz ... Esther Udina

   In reporter mice, subtypes of peripheral neurons show different regenerative capabilities after nerve injury and activate common pathways but also specific ones, indicating a different intrinsic growth response among them.
5. 1. Cell Biology
   2. Neuroscience

   Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

   Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata

   Drosophila model reveals that NTE/SWS-associated neurodegeneration is a lysosomal storage disorder accompanied by a leaky brain permeability barrier, abnormal fatty acid metabolism, and inflammation.
6. 1. Genetics and Genomics
   2. Neuroscience

   Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs

   Jiro Yoshino, Sonali S. Mali ... Jay Z. Parrish
7. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

   Matthew C. Pahl, Prabhat Sharma ... Andrew D. Wells
8. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture

   Teresa Attenborough, Kate A. Rawlinson ... Matthew Berriman
9. 1. Stem Cells and Regenerative Medicine

   Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

   Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine
10. 1. Chromosomes and Gene Expression
    2. Medicine

    LncRNA-Snhg3 Aggravates Hepatic Steatosis by Regulating PPARγ via SND1/H3K27me3

    Xianghong Xie, Mingyue Gao ... Xiaojun Liu