Rethinking group hunting

Latest research

1. 1. Cancer Biology

   Inhibition of ULK1/2 and KRAS^G12C controls tumor growth in preclinical models of lung cancer

   Phaedra C. Ghazi, Kayla T. O’Toole ... Martin McMahon
2. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture

   Teresa Attenborough, Kate A. Rawlinson ... Matthew Berriman
3. 1. Chromosomes and Gene Expression
   2. Medicine

   LncRNA-Snhg3 Aggravates Hepatic Steatosis by Regulating PPARγ via SND1/H3K27me3

   Xianghong Xie, Mingyue Gao ... Xiaojun Liu
4. 1. Cancer Biology
   2. Cell Biology

   mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3^IBTK-mediated ubiquitination of eIF4A1 in cancer cells

   Dongyue Jiao, Huiru Sun ... Kun Gao

   Overexpression of inhibitor of Bruton's tyrosine kinase contributes to the process of tumorigenesis by amplifying translation, represents a promising target for anti-cancer therapies.
5. 1. Neuroscience

   Inferring control objectives in a virtual balancing task in humans and monkeys

   Mohsen Sadeghi, Reza Sharif Razavian ... Dagmar Sternad

   A virtual balancing task with parallel experiments on human and non-human primates revealed a spectrum of behaviors (classified by a computational model into position, velocity, or mixed control strategy) that can serve as basis for analyzing neural population dynamics.
6. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

   Timothy A Bates, Mila Trank-Greene ... Fikadu G Tafesse
7. 1. Neuroscience

   A novel method for estimating properties of attentional oscillators reveals an age-related decline in flexibility

   Ece Kaya, Sonja A. Kotz, Molly J. Henry
8. 1. Computational and Systems Biology
   2. Physics of Living Systems

   Light-driven synchronization of optogenetic clocks

   Maria Cristina Cannarsa, Filippo Liguori ... Roberto Di Leonardo
9. 1. Cell Biology

   Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

   Jarno Mäkelä, Alexandros Papagiannakis ... Christine Jacobs-Wagner
10. 1. Immunology and Inflammation

    SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire

    Somen K Mistri, Brianna M. Hilton ... Jonathan E. Boyson