Rethinking group hunting

Latest research

1. 1. Cell Biology
   2. Neuroscience

   Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

   Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata

   Drosophila model reveals that NTE/SWS-associated neurodegeneration is a lysosomal storage disorder accompanied by a leaky brain permeability barrier, abnormal fatty acid metabolism, and inflammation.
2. 1. Cancer Biology

   Inhibition of ULK1/2 and KRAS^G12C controls tumor growth in preclinical models of lung cancer

   Phaedra C. Ghazi, Kayla T. O’Toole ... Martin McMahon
3. 1. Cell Biology
   2. Physics of Living Systems

   A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

   David T. McSwiggen, Helen Liu ... Hilary P. Beck
4. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture

   Teresa Attenborough, Kate A. Rawlinson ... Matthew Berriman
5. 1. Chromosomes and Gene Expression
   2. Medicine

   LncRNA-Snhg3 Aggravates Hepatic Steatosis by Regulating PPARγ via SND1/H3K27me3

   Xianghong Xie, Mingyue Gao ... Xiaojun Liu
6. 1. Cell Biology

   The non-mitotic role of HMMR in regulating the localization of TPX2 and the dynamics of microtubules in neurons

   Yi-Ju Chen, Shun-Cheng Tseng ... Eric Hwang
7. 1. Stem Cells and Regenerative Medicine

   Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

   Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine
8. 1. Biochemistry and Chemical Biology
   2. Developmental Biology

   Non-autonomous cell redox-pairs dictate niche homeostasis in multi-lineage stem populations

   Olivia Majhi, Aishwarya Chhatre ... Devanjan Sinha
9. 1. Microbiology and Infectious Disease

   Mycobacterium tuberculosis PhoP integrates stress response to intracellular survival by regulating cAMP level

   Hina Khan, Partha Paul ... Dibyendu Sarkar

   In a stress-specific manner, Mycobacterium tuberculosis PhoP regulates Rv0805 phosphodiesterase expression to control cAMP level and contributes to intracellular survival of the bacilli.
10. 1. Neuroscience

    Inferring control objectives in a virtual balancing task in humans and monkeys

    Mohsen Sadeghi, Reza Sharif Razavian ... Dagmar Sternad

    A virtual balancing task with parallel experiments on human and non-human primates revealed a spectrum of behaviors (classified by a computational model into position, velocity, or mixed control strategy) that can serve as basis for analyzing neural population dynamics.