Rethinking group hunting

Latest research

1. 1. Cell Biology
   2. Neuroscience

   Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

   Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata

   Drosophila model reveals that NTE/SWS-associated neurodegeneration is a lysosomal storage disorder accompanied by a leaky brain permeability barrier, abnormal fatty acid metabolism, and inflammation.
2. 1. Cancer Biology

   Inhibition of ULK1/2 and KRAS^G12C controls tumor growth in preclinical models of lung cancer

   Phaedra C. Ghazi, Kayla T. O’Toole ... Martin McMahon
3. 1. Stem Cells and Regenerative Medicine

   Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

   Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine
4. 1. Biochemistry and Chemical Biology
   2. Developmental Biology

   Non-autonomous cell redox-pairs dictate niche homeostasis in multi-lineage stem populations

   Olivia Majhi, Aishwarya Chhatre ... Devanjan Sinha
5. 1. Chromosomes and Gene Expression
   2. Medicine

   LncRNA-Snhg3 Aggravates Hepatic Steatosis by Regulating PPARγ via SND1/H3K27me3

   Xianghong Xie, Mingyue Gao ... Xiaojun Liu
6. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

   Matthew C. Pahl, Prabhat Sharma ... Andrew D. Wells
7. 1. Cell Biology

   Microtubule-dependent orchestration of centriole amplification in brain multiciliated cells

   Amélie-Rose Boudjema, Rémi Balagué ... Alice Meunier
8. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture

   Teresa Attenborough, Kate A. Rawlinson ... Matthew Berriman
9. 1. Genetics and Genomics
   2. Neuroscience

   Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs

   Jiro Yoshino, Sonali S. Mali ... Jay Z. Parrish
10. 1. Cell Biology

    The non-mitotic role of HMMR in regulating the localization of TPX2 and the dynamics of microtubules in neurons

    Yi-Ju Chen, Shun-Cheng Tseng ... Eric Hwang