UC Irvine biologists have discovered that fats within cells store a class of proteins with potent antibacterial activity, revealing a previously unknown type of immune system response that targets and kills bacterial infections.
Steven Gross, UCI professor of developmental & cell biology, and colleagues identified this novel intercellular role of histone proteins in fruit flies, and it could herald a new approach to fighting bacterial growth within cells. The study appears today in eLife, a new peer-reviewed, open-access journal supported by the Howard Hughes Medical Institute, the Max Planck Society and the Wellcome Trust.
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