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    1. Medicine
    2. Neuroscience

    Weak brain waves may warn of age-related neurodegenerative disease

    People with mild cognitive impairment or Alzheimer’s disease have weaker gamma waves in their brain than healthy peers, a discovery that may lead to new ways to diagnose these conditions.
    1. Developmental Biology

    Researchers identify gene linked to congenital heart disease

    Researchers have identified a gene that plays a minor role in congenital heart disease, using a combined approach that could aid studies of this and other multigenic diseases.

  3. Media Coverage: May roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in May 2021, including The Science Times, Business Insider and Psychology Today.
    1. Genetics and Genomics
    2. Neuroscience

    Scientists identify mechanism linking traumatic brain injury to neurodegenerative disease

    Study reveals that brain injuries can cause intracellular transport defects that can potentially lead to protein build-up and neurodegenerative disease.
    1. Medicine

    Mini bone marrow model predicts response to blood disorder treatment

    Scientists have described a miniature 3D bone marrow model that can both predict the response of patients to a new therapy for blood platelet disorders and facilitate studies to better understand these disorders.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Immune cells imperfect at distinguishing between friend and foe, study suggests

    A new study that upends the idea that T cells can perfectly distinguish between healthy and infected cells may lead to improved approaches to treating cancer and autoimmune diseases.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Impaired dopamine transporters contribute to Parkinson’s disease-like symptoms

    A rare mutation that causes a Parkinson’s disease-like disorder in young children interferes with dopamine transporters in the brain, suggesting that treatments targeting the transporters may be beneficial.
    1. Genetics and Genomics
    2. Neuroscience

    Scientists map gene changes underlying brain and cognitive decline in aging

    Personalised models of cognitive decline offer novel insights into the multiscale alterations in the elderly and diseased brain, with important implications for identifying future treatment targets.
    1. Evolutionary Biology

    Mathematical model predicts effect of bacterial mutations on antibiotic success

    Findings suggest measuring the number of mutations that lead to antibiotic resistance in bacteria is crucial for determining how likely antibiotics are to fail, and should be used to inform new treatment strategies aimed at preventing resistance evolution.
    1. Medicine

    New model helps predict heart attacks in high-risk patients

    Researchers have described a new approach to analysing the forces at play behind diseased heart vessels, which could help cardiologists predict heart attacks in patients.
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