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    1. Ecology
    2. Evolutionary Biology

    Birds’ high blood sugar defies ageing expectations

    A large-scale comparative study suggests that some birds have evolved mechanisms to avoid the harmful effects of high blood sugar, granting insights into metabolism and ageing.
    1. Cell Biology
    2. Genetics and Genomics

    Blood metabolites may reduce genetic risk of glaucoma

    An algorithm based on blood metabolites improves on current glaucoma genetic risk scores and pinpoints metabolites that might protect against the disease.

  3. eLife wins industry-renowned UX Award 2025

    eLife has been announced the winner of this year’s OpenAthens UX Award for its user-driven approach to Reviewed Preprints.
    1. Microbiology and Infectious Disease

    New 3D imaging approach reveals intricate steps of virus assembly

    A new integrated 3D imaging approach combines cryo-light microscopy and soft X-ray tomography to reveal the intricate ultrastructure of herpes simplex virus-1 assembly.

  5. eLife welcomes five new members to Board of Directors

    With their collective track record of active leadership, the new board members will help direct eLife in its mission to transform research communication for all.
    1. Ecology
    2. Evolutionary Biology

    Fossils reveal rapid land recovery after end-Permian extinction

    Fossil evidence from North China suggests that some ecosystems may have recovered within just two million years of the end-Permian mass extinction, much sooner than previously thought.
    1. Computational and Systems Biology
    2. Cancer Biology

    New computational tool could improve discovery of cancer treatments

    Scientists have developed retriever, a computational tool that extracts disease-specific drug response signatures to predict the best combinations for cancer treatment.
    1. Developmental Biology

    Cell polarity coordinates jellyfish larval development along a central axis

    Researchers have discovered that a single molecule, Wnt3, coordinates a two-step process of cell polarity orientation that enables jellyfish embryos to develop around a central axis, shedding light on how the body plans of early animals evolved.
    1. Cancer Biology

    Sustained inhibitor treatment shows promise for drug-resistant breast cancer

    Maintaining treatment with CDK4/6 inhibitors significantly suppresses the growth of breast cancer cells, even after drug resistance has developed, according to new research.
    1. Biochemistry and Chemical Biology

    Study suggests stalled amyloid protein production drives Alzheimer’s disease

    A study of rare familial genetic mutations linked to early-onset dementia supports the idea that stalled protein processing contributes to Alzheimer’s disease.
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