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Latest research

    1. Computational and Systems Biology

    Integrative small and long RNA omics analysis of human healing and nonhealing wounds discovers cooperating microRNAs as therapeutic targets

    Zhuang Liu et al.
    A comprehensive microRNA expression and function landscape of human wounds unraveled miRNAs highly relevant to venous ulcer pathology.
    1. Neuroscience

    Flexible and efficient simulation-based inference for models of decision-making

    Jan Boelts et al.
    A new machine learning method makes it possible to efficiently identify the parameters of cognitive models using Bayesian inference, even when only model simulations are available.
    1. Cell Biology

    CXCR4high megakaryocytes regulate host-defense immunity against bacterial pathogens

    Jin Wang et al.
    scRNA-seq identified CXCR4high MKs can funtionally regulate host-defense immune response against bacterial infection.
    1. Cell Biology

    Ubiquitination drives COPI priming and Golgi SNARE localization

    Swapneeta S Date et al.
    The ability of COPI to bind polyubiquitin is a key determinant for SNARE incorporation into intracellular vesicles and for maintenance of a functional Golgi complex.
    1. Cell Biology

    Distinct roles for two Caenorhabditis elegans acid-sensing ion channels in an ultradian clock

    Eva Kaulich et al.
    Two acid-sensing members of the degenerin/epithelial sodium channel family play distinct roles in controlling different aspects of rhythmic proton and calcium oscillations in the nematode intestine.
    1. Stem Cells and Regenerative Medicine

    Generation of functional hepatocytes by forward programming with nuclear receptors

    Rute A Tomaz et al.
    Forward programming of human pluripotent stem cells with a combination of four transcription factors allows the production of functional hepatocytes.
    1. Physics of Living Systems

    Learning to predict target location with turbulent odor plumes

    Nicola Rigolli et al.
    Intensity of an odor and timing of its detection are complementary attributes of turbulent plumes and enable robust prediction of the location of a distant target.