Highlights

  • Tsetse fly feeding adaptations

    Investigations into the biomechanics of tsetse fly blood feeding reveal that subtle anatomical adaptations enable the penetration of a diverse range of host hides.

    Stephan Löwe, Laura Hauf ... Markus Engstler
    Research Article
  • Anatomy of taste and texture

    Comprehensive ultrastructural reconstruction of the Drosophila larval pharyngeal sensory system reveals the organization and diversity of its sensory structures.

    Vincent Richter, Tilman Triphan ... Andreas S Thum
    Research Article
  • Settling down at sunset

    Transcriptomic and epigenomic profiling reveals how diminishing light induces chromatin accessibility and primes larval settlement in Amphimedon queenslandica.

    Huifang Yuan, Oceane Blard ... Sandie M Degnan
    Research Article
  • Neurosecretory connections

    Connectomic and transcriptomic analyses reveal the anatomical and functional organisation of neurosecretion in the Drosophila brain.

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Research Article
  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife
  • Explore our new collection

    Delve into leading research on Lifestyle, Environment and Epigenetic Inheritance.

    Collection

Latest research

    1. Neuroscience

    Longitudinal analysis of visuomotor orientation after optic lobe lesions reveals brain plasticity in Drosophila

    Margarida Caio, Dean Rance, Christa Rhiner
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Interocular suppression weakens binocular disparity integration in the dorsal visual stream

    Rong Jiang, Ming Meng
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Metabolically Activated Proteostasis Regulators Reduce Differentiation of CD4+ TH17 Cells

    Priyadarshini Chatterjee, Keishla Sánchez Ortiz ... R Luke Wiseman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Ecology

    Healed predation scar on a Cambrian apex predator

    Kun-sheng Du, Yu Wang ... Wei Li
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Neuroscience

    A structured-illumination miniscope for optically sectioned imaging and real-time neural decoding

    Huixin Lin, Shu Wang ... Jingfeng Zhou
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Retrieval practice prevents stress-induced inference impairment and preserves rapid bridge-related memory reactivation

    Jinpeng Guo, Ruixin Chen ... Wei Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Developmental prosopagnosics have normal spatial integration in posterior ventral face-selective regions

    Daniel A Stehr, Yiyuan Zhang ... Bradley Duchaine
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Evolutionary Biology
    2. Genetics and Genomics

    Cis-regulation and natural selection in the evolution of human DNA methylation

    Zhenzhen Ma, Alexander L Starr ... Hunter B Fraser
    Cis-acting changes account for most methylation divergence between humans and chimpanzees, with lineage-specific selection on gene expression and promoter methylation at pathways tied to human speech, cognition, and disease susceptibility.
    1. Neuroscience
    2. Physiology

    Synthetic torpor in the rat protects the heart from ischaemia-reperfusion injury

    Megan Elley, Ludovico Taddei ... Michael Ambler
    Synthetic torpor induced in a species that does not naturally hibernate protects the heart from ischaemia-reperfusion injury, pointing to a novel translatable strategy for improving outcomes after myocardial infarction.
    1. Neuroscience

    Learning-associated flexibility of cortical taste coding is impaired in Shank3 knockout mice

    Chi-Hong Wu, Gina G Turrigiano
    Loss of Shank3 destabilizes neuronal activity in the taste cortex and impairs aversive taste learning in mice, revealing how autism-associated genes compromise flexible sensory encoding in sensory cortices to influence behavior.