Highlights

  • Hypoxia to healthspan

    Genetic tools highlight potential signalling components underlying hypoxia-induced longevity in C. elegans.

    Elizabeth S Kitto, Shijiao Huang ... Scott F Leiser
    Reviewed Preprint Updated
  • Symbionts shape pest traits

    Novel endosymbiotic bacteria have contrasting effects on the performance and dispersal of Russian wheat aphids and on the severity of damage caused to cereal host plants.

    Xinyue Gu, Alex Gill ... Ary A Hoffmann
    Reviewed Preprint Updated
  • Neurosecretory connections

    Connectomic and transcriptomic analyses reveal the anatomical and functional organisation of neurosecretion in the Drosophila brain.

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Reviewed Preprint Updated
  • Mapping regulatory DNA

    Cis-regulatory elements in the large genome of Parhyale hawaiensis can be identified by integrating chromatin accessibility and sequence conservation data.

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Research Article
  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife
  • Explore our new collection

    Delve into leading research on Lifestyle, Environment and Epigenetic Inheritance.

    Collection

Latest research

    1. Neuroscience

    Effects of nicotine compared to placebo gum on sensitivity to pain and mediating effects of peak alpha frequency

    Samantha K Millard, Alan KI Chiang ... David A Seminowicz
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Solid
    • Incomplete
    1. Neuroscience

    Deep anatomical and ultrastructural classification of neurons in the zebrafish olfactory bulb

    Nila R Mönig, Michał Januszewski ... Rainer W Friedrich
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Evidence for flexible regulation of movement and decision vigor in a reward-oriented task

    Adrien Conessa, Arnaud Boutin, Bastien Berret
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Small circuit principles for learning in large worlds

    Dhruva V Raman, Christopher R Dunne ... Timothy O’Leary
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Biochemistry and Chemical Biology

    Cell cycle-coupled CK1δ turnover, autoinhibition, and activity

    Fidel E Serrano, Bianca Ruppert ... Michael Brunner
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Two Interacting Neural Processes Support Speech Planning during Naturalistic Conversation

    Hiroyoshi Yamasaki, Philippe Blache, Daniele Schön
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Physiology

    Reproductive experience promotes permanent body growth independently of growth hormone

    Gabriel O de Souza, Willian O dos Santos ... Jose Donato
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Ecology

    Novel but stable endosymbionts have contrasting effects on aphid dispersal and plant feeding damage in the cereal pest Diuraphis noxia

    Xinyue Gu, Alex Gill ... Ary A Hoffmann
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Fast-ripples are emergent properties of neuronal networks

    Laurent Sheybani, Yichen Qiu ... Matthew C Walker
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing