Latest research

1. 1. Neuroscience

   Entrained neuronal activity to periodic visual stimuli in the primate striatum compared with the cerebellum

   Masashi Kameda et al.

   Neurons in the striatum exhibited periodic firing in monkeys attempting to detect omission of repetitive visual stimulus, while the phase of neuronal activity differed from that observed in the cerebellum.
2. 1. Cell Biology
   2. Plant Biology

   Two mechanisms regulate directional cell growth in Arabidopsis lateral roots

   Charlotte Kirchhelle et al.

   In lateral roots, cells employ a novel pathway to cell edges to control directional growth, which acts independently of the leading paradigm of oriented deposition of cellulose microfibrils at faces.
3. 1. Cell Biology
   2. Human Biology and Medicine

   Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity

   Kasparas Petkevicius et al.

   Obesity leads to increased phosphatidylcholine turnover in adipose tissue macrophages that makes them susceptible to saturated fatty acid-induced inflammation.
4. 1. Immunology and Inflammation

   Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells

   David G Saliba et al.

   TCR and CD40L microclusters are linked in synaptic ectosomes (extracellular vesicles) and released in the immunological synapse by helper T cells and induce dendritic cell maturation and cytokine production.
5. 1. Neuroscience

   Evolution of neuronal anatomy and circuitry in two highly divergent nematode species

   Ray L Hong et al.

   The substrate for evolutionary divergence does not lie in changes in neuronal cell number or targeting, but rather in sensory perception and synaptic partner choice within invariant, prepatterned neuronal processes.
6. 1. Cell Biology

   A critical role of VMP1 in lipoprotein secretion

   Hideaki Morishita et al.

   The ER transmembrane protein VMP1 is important for release of lipoproteins from the ER membrane into the ER lumen for secretion.
7. 1. Developmental Biology

   Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6

   Yi Xin et al.
8. 1. Genetics and Genomics
   2. Neuroscience

   Learning is enhanced by tailoring instruction to individual genetic differences

   David G Mets, Michael S Brainard

   Tailoring instructive experience to individual genetic biases improves vocal learning outcomes across genetic backgrounds in the Bengalese finch.
9. 1. Biochemistry and Chemical Biology

   Mechanisms of iron- and O₂-sensing by the [4Fe-4S] cluster of the global iron regulator RirA

   Ma Teresa Pellicer Martinez et al.

   Molecular details of how the iron–sulfur cluster cofactor of a bacterial global iron regulatory protein simultaneously senses iron and O₂ are revealed by mass spectrometry and spectroscopy.
10. 1. Epidemiology and Global Health

    Multivariable two-sample Mendelian randomization estimates of the effects of intelligence and education on health

    Neil Martin Davies et al.

    Many of the effects of intelligence on health and social outcomes later in life are mediated via education.