Highlights

  • X-rays impact gene expression

    Exposing the wing discs of Drosophila to X-rays leads to heterogenous changes in gene expression that are related to cell-cycle status and cell location.

    Joyner Cruz, Willam Y Sun ... Iswar K Hariharan
    Reviewed Preprint Updated

  • Reprogramming progenitor cells

    Progenitor cells destined to become glial cells can be reprogrammed to become corticospinal-like neurons

    Abdulkadir Ozkan, Hari K Padmanabhan ... Jeffrey D Macklis
    Research Article

  • Nanosprings probe motor proteins

    DNA nanosprings can measure stall forces in kinesin motor proteins, highlighting their potential as a new tool for force spectroscopy in biophysics.

    Nobumichi Takamatsu, Hiroko Furumoto ... Kumiko Hayashi
    Reviewed Preprint Updated

  • Research culture

    The Researcher Development Concordat has led to improvements in research culture in the UK, but there is still more to do.

    Robert AR Drake, Laura A Gray ... Joan Chang
    Feature Article

  • Where theory meets biology

    eLife author Veronika Koren, a computational neuroscientist, answers questions about her work on efficient coding.

    Inside eLife

  • What is a Reviewed Preprint?

    Reviewed Preprints provide benefits to authors and to the wider scientific community.

    Inside eLife
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    Alcohol Attenuates CRF-Induced Excitatory Effects from the Extended Amygdala to Dorsostriatal Cholinergic Interneurons

    Amanda Essoh, Xueyi Xie ... Jun Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Efficient and reproducible pipelines for spike sorting large-scale electrophysiology data

    Alessio P Buccino, Arjun Sridhar ... Joshua H Siegle
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Neuroscience

    Improved sensory representations as a result of temporal adaptation

    Amber Marijn Brands, Zilan Oz ... Iris Isabelle Anna Groen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Jam2 Signaling Functions Downstream of Hand2 To Initiate The Formation Of Organ-Specific Vascular Progenitors In Zebrafish

    Martyna Griciunaite, Julius Martinkus ... Saulius Sumanas
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing

    Katrina Bartas, Pieter Derdeyn ... Kevin T Beier
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    High-Throughput Quantification of Population Dynamics using Luminescence

    Malte Muetter, Daniel Angst ... Sebastian Bonhoeffer
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Disentangling Cephalopod Chromatophores Motor Units with Computer Vision

    Mathieu DM Renard, Johann Ukrow ... Gilles Laurent
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys

    Kathryn Branam, Joshua I Gold, Long Ding
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Computational and Systems Biology

    Automated genome mining predicts structural diversity and taxonomic distribution of peptide metallophores across bacteria

    Zachary L Reitz, Bita Pourmohsenin ... Marnix H Medema
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Multi-Scale Anti-Correlated Neural States Dominate Naturalistic Whole-Brain Activity

    Dora Gözükara, Djamari Oetringer ... Linda Geerligs
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
Load more

Magazine

    1. Medicine
    2. Structural Biology and Molecular Biophysics

    Medical Imaging: MRI sets its sights on collagen

    Fritz Schick
    1. Developmental Biology

    Limb Patterning: The cellular logic of limb regeneration

    Matthew Cherubino, Catherine D McCusker
    1. Neuroscience

    Aging: Linking neuron-glia interactions and longevity

    Michael Pokrass, Nan Hao

  4. Research Culture: Going beyond compliance to build on the Researcher Development Concordat

    Robert AR Drake, Laura A Gray ... Joan Chang
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Chromosomes: Finding a role for non-coding DNA in trypanosomes

    Markus R Schmidt
    1. Cancer Biology
    2. Cell Biology

    Chemotherapy: Lipid balance and chemoresistance in cancer cells

    Kaori Kanemaru, Yoshikazu Nakamura
    1. Genetics and Genomics
    2. Physics of Living Systems

    Raman Spectroscopy: Probing the proteome

    Wei-Hsiang Lin, Chia-Liang Cheng
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
Back to top