Highlights

Latest research

    1. Evolutionary Biology
    2. Neuroscience

    Whole-brain comparison of rodent and human brains using spatial transcriptomics

    Antoine Beauchamp, Yohan Yee ... Jason P Lerch
    A novel machine learning approach improves quantitative comparisons of mouse and human brains using spatial transcriptomics data sets.
    1. Ecology

    Latent functional diversity may accelerate microbial community responses to temperature fluctuations

    Thomas P Smith, Shorok Mombrikotb ... Thomas Bell
    A novel species-sorting experiment finds that phylogenetically and functionally distinct microbial communities emerge under different temperature conditions due to the resuscitation of latent diversity.
    1. Computational and Systems Biology
    2. Developmental Biology

    Large-scale analysis and computer modeling reveal hidden regularities behind variability of cell division patterns in Arabidopsis thaliana embryogenesis

    Elise Laruelle, Katia Belcram ... Philippe Andrey
    Self-organization based on a feedback loop between cell geometry and division plane positioning plays a central role in the building of tissue architectures in Arabidopsis thaliana embryo through both stereotyped and variable division patterns.
    1. Neuroscience

    Coordinated multiplexing of information about separate objects in visual cortex

    Na Young Jun, Douglas A Ruff ... Jennifer M Groh
    Two distinct objects evoke fluctuating activity in visual cortex in a manner that could preserve information about both items.
    1. Neuroscience

    Functional connectivity subtypes associate robustly with ASD diagnosis

    Sebastian GW Urchs, Angela Tam ... Pierre Bellec
    Unsupervised clustering of the heterogeneous functional brain organization in autism reveals generalizable patterns of connectivity alterations that extend to the general population.
    1. Cell Biology

    A motor neuron disease-associated mutation produces non-glycosylated Seipin that induces ER stress and apoptosis by inactivating SERCA2b

    Shunsuke Saito, Tokiro Ishikawa ... Kazutoshi Mori
    When non-glycosylated, Seipin, which spans the endoplasmic reticulum (ER) membrane twice, forms aggregates in an oligomerization-dependent manner, distorts the shape of the ER, and incorporates SERCA2b via direct interaction, inactivation of which results in induction of ER stress and apoptosis.
    1. Neuroscience

    Improving the accuracy of single-trial fMRI response estimates using GLMsingle

    Jacob S Prince, Ian Charest ... Kendrick N Kay
    GLMsingle is a publicly available toolbox for analyzing fMRI time-series data that leverages data-driven optimization techniques to improve the accuracy of single-trial BOLD response estimates.
    1. Cell Biology
    2. Physics of Living Systems

    Fixation can change the appearance of phase separation in living cells

    Shawn Irgen-Gioro, Shawn Ryohei Yoshida ... Shasha Chong