Highlights

  • Symbionts shape pest traits

    Novel endosymbiotic bacteria have contrasting effects on the performance and dispersal of Russian wheat aphids and on the severity of damage caused to cereal host plants.

    Xinyue Gu, Alex Gill ... Ary A Hoffmann
    Reviewed Preprint Updated

  • Neurosecretory connections

    Connectomic and transcriptomic analyses reveal the anatomical and functional organisation of neurosecretion in the Drosophila brain.

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Research Article

  • Replication in Drosophila studies

    An analysis of 400 articles on the immune response in Drosophila highlights a need for caution regarding the replicability of certain claims.

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Reviewed Preprint Updated

  • Hypoxia to healthspan

    Genetic tools highlight potential signalling components underlying hypoxia-induced longevity in C. elegans.

    Elizabeth S Kitto, Shijiao Huang ... Scott F Leiser
    Reviewed Preprint Updated

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Explore our new collection

    Delve into leading research on Lifestyle, Environment and Epigenetic Inheritance.

    Collection
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A Sterol-Binding Cavity Underlies Sterol Recognition and Differential Activation of the ABCG5/G8

    Fatemeh Rezaei, Isra F Omar ... Jyh-Yeuan Lee
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    Cross-Kingdom Control: Yeast Prion Protein [MRPL10+] Modulates Host Physiology in Drosophila

    Chih-Chun Janet Lin, Jessica Y Jiang ... Andrew G Clark
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Evolutionary Biology

    Fitness flux in SARS-CoV-2 and influenza H3N2

    Trevor Bedford
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Glia regulate local retinoic acid levels to specify neuronal specialisation for high-acuity vision

    Manuela Lahne, Roxana Lungu ... Ryan B MacDonald
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Identifying Novel Estrogenic Mitochondrial Targets in Hypothalamic Proopiomelanocortin Neurons by Chemoproteomics

    Jian Qiu, Martha A Bosch ... Martin J Kelly
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Real-Time Embodied Experience Shapes High-Level Reasoning Under Altered Gravity

    Hélène Grandchamp des Raux, Tommaso Ghilardi ... Ori Ossmy
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Incomplete
    1. Developmental Biology

    A stress-responsive morphogenetic program of the uterine epithelium safeguards the establishment of early pregnancy

    Chihiro Ishizawa, Shizu Aikawa ... Yasushi Hirota
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Single neurons detect spatiotemporal activity transitions through STP and EI imbalance

    Aditya Asopa, Upinder Singh Bhalla
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    In vivo virus-free lineage tracing and live imaging reveal that NeuroD1 does not reprogram microglia into neurons

    Xiaoyu Li, Yuxin Li ... Yanxia Rao
    Genetic lineage tracing and live-cell imaging demonstrate that NeuroD1 does not convert microglia into neurons but instead promotes microglial apoptosis, challenging claims of in situ glia-to-neuron conversion.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Separable downmodulation of meiotic axis protein deposition and DNA break induction at chromosome ends

    Adhithi R Raghavan, Kieron May ... Andreas Hochwagen
    Meiotic axis protein deposition and double-strand break formation near yeast chromosome ends are regulated by multiple distinct layers of regulation, including the chromatin modifiers Sir2/3 and Dot1.
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Magazine

    1. Microbiology and Infectious Disease

    Bird Flu: The cow udder as an influenza mixing ground

    Silke Rimaux, Robert P de Vries
    1. Computational and Systems Biology

    AI in Science: The 42 problem in AI-assisted research

    Giovanni Spitale, Federico Germani
    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan

  4. Research Culture: From East to West – an early-career researcher’s voyage across continents

    Samuel C Eziuzor
  5. Close-up of an iris

    Episode 105: September 2026

    1. Cell Biology
    2. Computational and Systems Biology

    Philosophy of Biology: The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    1. Genetics and Genomics

    Environmental Learning: How experience shapes individuality

    Bassem A Hassan
  8. See more Magazine articles

Categories

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