Latest research

1. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   An atlas of the binding specificities of transcription factors in Pseudomonas aeruginosa directs prediction of novel regulators in virulence

   Tingting Wang et al.

   The transcription factor (TF)-binding specificities of Pseudomonas aeruginosa allow us to predict virulence-associated TFs and their target genes, which will facilitate to find effective treatment and prevention for its associated diseases.
2. 1. Microbiology and Infectious Disease

   Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4⁺ T cells

   Jinfeng Cai et al.

   A novel reporter model system serves as a valuable tool for studying latent HIV-1 infection and identifies potent latency reversing agent.
3. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation

   Philipp Kolb et al.

   Molecular mechanisms reveal that human cytomegalovirus has evolved to deploy two individual glycoproteins working in synergy to efficiently evade antibody-mediated immunity mediated by Fc-gamma receptors.
4. 1. Neuroscience

   Signed and unsigned reward prediction errors dynamically enhance learning and memory

   Nina Rouhani, Yael Niv

   Throughout learning, both unexpected outcomes and the predictive value of cues modulate learning rate and episodic memory, thereby supporting two seemingly opposing theories of associative learning.
5. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth

   Deniz Cizmeci et al.

   Extended somatic hypermutation and clonal evolution associated with antibody neutralization breath in HIV controllers with low plasma viral loads provide promise for HIV vaccine development.
6. 1. Neuroscience

   Distinct neuronal populations contribute to trace conditioning and extinction learning in the hippocampal CA1

   Rebecca A Mount et al.
7. 1. Evolutionary Biology

   The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus

   Joshua T Washington et al.
8. 1. Cell Biology
   2. Immunology and Inflammation

   Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node

   Shannon M Walsh et al.
9. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   Morphological and genomic shifts in mole-rat 'queens' increase fecundity but reduce skeletal integrity

   Rachel A Johnston et al.
10. 1. Neuroscience

    Gamma rhythms and visual information in mouse V1 specifically modulated by somatostatin⁺ neurons in reticular thalamus

    Mahmood S Hoseini et al.