Latest research

1. 1. Plant Biology

   Proximity labeling of protein complexes and cell type-specific organellar proteomes in Arabidopsis enabled by TurboID

   Andrea Mair et al.
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   A distinct transition from cell growth to physiological homeostasis in the tendon

   Mor Grinstein et al.
3. 1. Neuroscience

   ON selectivity in Drosophila vision is a multisynaptic process involving both glutamatergic and GABAergic inhibition

   Sebastian Molina-Obando et al.
4. 1. Developmental Biology
   2. Evolutionary Biology

   A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle

   Glenda Comai et al.

   Tbx1-Isl1-Met defines a unique genetic hierarchy that regulates esophagus myogenesis and patterning in the mouse.
5. 1. Plant Biology
   2. Structural Biology and Molecular Biophysics

   Protein engineering expands the effector recognition profile of a rice NLR immune receptor

   Juan Carlos De la Concepcion et al.
6. 1. Structural Biology and Molecular Biophysics

   Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

   Jie Li et al.
7. 1. Neuroscience

   RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses

   Marisa M Brockmann et al.

   The active zone scaffold protein RIM-BP2 performs distinct functions in vesicle release at two hippocampal synapses, providing insights on how synapses express diversity in release properties.
8. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia

   Xuchen Hu et al.

   Macrophages release 30-nm vesicular particles enriched in accessible cholesterol during cellular locomotion, a discovery that is likely relevant to cholesterol disposal by these cells.
9. 1. Epidemiology and Global Health
   2. Structural Biology and Molecular Biophysics

   Electron cryo-microscopy of bacteriophage PR772 reveals the elusive vertex complex and the capsid architecture

   Hemanth KN Reddy et al.

   The structure and composition of the elusive vertex complex in Tectiviridae is finally revealed and the newly reported protein conformations help to maintain the capsid architecture.
10. 1. Evolutionary Biology

    Molecular function limits divergent protein evolution on planetary timescales

    Mariam M Konaté et al.

    Orthologous proteins that continuously maintain the same molecular function do not usually diverge beyond a certain level of sequence and structural similarity.