Latest research

1. 1. Developmental Biology
   2. Structural Biology and Molecular Biophysics

   A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity

   Chen Qiu et al.

   A Caenorhabitis elegans RNA-binding protein, FBF-2, modulates RNA sequence motif recognition through conformational change and partner protein interaction.
2. 1. Evolutionary Biology
   2. Genetics and Genomics

   Self-sperm induce resistance to the detrimental effects of sexual encounters with males in hermaphroditic nematodes

   Lauren N Booth et al.

   Nematode hermaphroditism has co-evolved with a self-sperm sensing mechanism that protects hermaphrodites from the detrimental effects of mating with males.
3. 1. Genetics and Genomics

   Insulin-like peptides and the mTOR-TFEB pathway protect Caenorhabditis elegans hermaphrodites from mating-induced death

   Cheng Shi et al.

   Hermaphroditic Caenorhabditis elegans slow the onset of mating-induced death through self-sperm-regulated insulin-like gene expression, which regulates the activity of the IIS/FOXO pathway, mTOR signaling, and the TFEB/HLH-30 transcription factor.
4. 1. Neuroscience

   MagC, magnetic collection of ultrathin sections for volumetric correlative light and electron microscopy

   Thomas Templier

   The augmentation of resin-embedded sample blocks with magnetic resin allows remote actuation of ultrathin sections and deposition at high packing density onto silicon wafers for correlative light and electron microscopy.
5. 1. Computational and Systems Biology
   2. Neuroscience

   Multivariate stochastic volatility modeling of neural data

   Tung D Phan et al.

   Multivariate stochastic volatility models provide insights into understanding the dynamics and connectivity of neural signals during cognitive tasks.
6. 1. Biochemistry and Chemical Biology
   2. Computational and Systems Biology

   Profiling the Escherichia coli membrane protein interactome captured in Peptidisc libraries

   Michael Luke Carlson et al.

   Trapping of the cell envelope proteome into water-soluble peptidisc library allows high-throughput definition of the membrane protein interactome.
7. 1. Evolutionary Biology
   2. Microbiology and Infectious Disease

   Apicomplexan-like parasites are polyphyletic and widely but selectively dependent on cryptic plastid organelles

   Jan Janouškovec et al.
8. 1. Cell Biology
   2. Human Biology and Medicine

   Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity

   Kasparas Petkevicius et al.
9. 1. Evolutionary Biology
   2. Genetics and Genomics

   Testis single-cell RNA-seq reveals the dynamics of de novo gene transcription and germline mutational bias in Drosophila

   Evan Witt et al.

   Single-cell RNA-sequencing and germline substitutions provide novel insights into how testis is a hotspot for evolutionary innovation of genes, expression, and mutation at the single-cell level.
10. 1. Genetics and Genomics
    2. Plant Biology

    Epigenetic silencing of a multifunctional plant stress regulator

    Mark Zander et al.