Latest research

1. 1. Developmental Biology

   In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration

   Mira I Pronobis et al.

   Proximity labeling-based proteomic strategies applied in zebrafish identify new insights into protein network changes in heart muscle cells during regeneration and implicate Rho A as a target of ErbB2 signaling during zebrafish heart regeneration.
2. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Complementary biosensors reveal different G-protein signaling modes triggered by GPCRs and non-receptor activators

   Mikel Garcia-Marcos

   Heterotrimeric G-proteins can be switched on not only by G-protein-coupled receptors but also by cytoplasmic proteins, resulting in different signaling mechanisms in cells depending on the specific type of activator.
3. 1. Cell Biology
   2. Developmental Biology

   The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium

   Patrick Morley Willoughby et al.

   Rab25a and Rab25b mutant embryos exhibit epithelial spreading delays during morphogenesis and are characterized by cytokinesis defects leading to cell fusions, heterogeneous epithelial cell sizes, and reduced cortical actomyosin contractility.
4. 1. Immunology and Inflammation
   2. Medicine

   An open label trial of anakinra to prevent respiratory failure in COVID-19

   Evdoxia Kyriazopoulou et al.

   Early suPAR-guided anakinra decreases the risk for severe respiratory failure in SARS-CoV-2 pneumonia and restores the pro-/anti-inflammatory balance.
5. 1. Epidemiology and Global Health
   2. Medicine

   Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: a controlled before-and-after trial

   Jackie Knee et al.
6. 1. Microbiology and Infectious Disease

   Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation

   Mart M Lamers et al.
7. 1. Cell Biology
   2. Computational and Systems Biology

   Artistoo, a library to build, share, and explore simulations of cells and tissues in the web browser

   Inge M N Wortel, Johannes Textor
8. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   NusG is an intrinsic transcription termination factor that stimulates motility and coordinates gene expression with NusA

   Zachary F Mandell et al.
9. 1. Cell Biology
   2. Medicine

   Augmenter of Liver Regeneration regulates cellular iron homeostatis by modulating mitochondrial transport of ATP-binding cassette B8

   Hsiang-Chun Chang et al.
10. 1. Developmental Biology

    Spatiotemporal recruitment of RhoGTPase protein GRAF inhibits actomyosin ring constriction in Drosophila cellularization

    Swati Sharma, Richa Rikhy