Highlights

Latest research

    1. Developmental Biology

    The NTR/Prodrug Revolution: Tools for Controlling Cell Loss and Regeneration

    Gha-Hyun J Kim, Michael J Parsons
    Not revised
    Reviewed Preprint v1
    1. Chromosomes and Gene Expression
    2. Medicine

    Gene dosage imbalance disrupts systemic metabolism in the Dp16 Down syndrome mouse model

    Fangluo Chen, Muzna Saqib ... G William Wong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    The Multifaceted Role of EXOC6A in Ciliogenesis

    Te-Lin Lin, Chien-Ting Wu, Tang K Tang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    Membrane curvature regulates Ups1 dependent phosphatidic acid transfer across lipid bilayers

    Fereshteh Sadeqi, Dexin Dong ... Michael Meinecke
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Immunology and Inflammation

    Nociceptor neurons control pollution-mediated neutrophilic asthma

    Jo-Chiao Wang, Amelia Kulle ... Sebastien Talbot
    Air pollution activates macrophage-derived artemin, sensitizing TRPA1 nociceptors to drive neutrophilic asthma, revealing new therapeutic targets for refractory airway inflammation.
    1. Neuroscience

    Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons

    Malin Schmidt, Anne Hoffrichter ... Philipp Koch
    Psilocin induces a durable neuroplastic state in human cortical neurons by enhancing BDNF signaling, neurite complexity, synaptogenesis, and synaptic network activity through 5-HT2A receptor-dependent mechanisms.
    1. Neuroscience

    Human exploration strategically balances approaching and avoiding uncertainty

    Yaniv Abir, Michael Neil Shadlen, Daphna Shohamy
    Strategic avoidance of uncertainty emerges under high cognitive demands, enabling faster decisions without impairing learning.
    1. Cell Biology
    2. Neuroscience

    Death receptor 6 does not regulate axon degeneration and Schwann cell injury responses during Wallerian degeneration

    Bogdan Beirowski, Haoran Huang, Elisabetta Babetto
    Rigorous analysis in two knockout mouse lines demonstrates that death receptor 6 is not required for axon degeneration or Schwann cell injury responses following peripheral nerve transection.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Genetics and Genomics

    A pilot study for whole proteome tagging in C. elegans

    Matthew Eroglu, Oliver Hobert
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    DNA tensiometer reveals catch-bond detachment kinetics of kinesin-1, -2 and -3

    Crystal R Noell, Tzu-Chen Ma ... William O Hancock
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing