Highlights

Latest research

    1. Ecology

    Full factorial construction of synthetic microbial communities

    Juan Diaz-Colunga, Pablo Catalan ... Alvaro Sanchez
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Structural Biology and Molecular Biophysics

    Bifunctional Architecture Enables Substrate Catalysis and Channeling in Paracoccus TMAO Demethylase

    Trung Thach, KanagaVijayan Dhanabalan ... Ramaswamy Subramanian
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Reassessing prediction in the brain: Pre-onset neural encoding during natural listening does not reflect pre-activation

    Sahel Azizpour, Britta U Westner ... Linda Geerligs
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Adult-neurogenesis allows for representational stability and flexibility in early olfactory system

    Zhen Chen, Krishnan Padmanabhan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Computational and Systems Biology

    Fully computational design of PAM-relaxed Staphylococcus aureus Cas9 with expanded targeting capability using UniDesign

    Youcai Xiong, Li-Kuang Tsai ... Xiaoqiang Huang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics
    2. Neuroscience

    Morphine regulates astrocyte transcriptional dynamics in the ventral tegmental area by stimulation of glucocorticoid signaling

    Jennifer J Tuscher, Angela Cleere ... Jeremy J Day
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology
    2. Immunology and Inflammation

    HEB collaborates with TCR signaling to upregulate Id3 and enable γδT17 cell maturation in the fetal thymus

    Johanna S Selvaratnam, Juliana DB da Rocha ... Michele Kay Anderson
    Dynamic regulation of the E-protein/Id axis links TCR signaling to the maturation of IL-17-producing γδ T cells.
    1. Neuroscience

    Multiple functions of cerebello-thalamic neurons in learning and offline consolidation of a motor skill in mice

    Andrés Pablo Varani, Caroline Mailhes-Hamon ... Daniela Popa
    Distinct cerebellar projections to the forebrain differentially support acquisition and offline consolidation of a motor skill engaging cerebello-striato-cortical circuits, revealing the temporal and functional diversity of cerebellar contributions to learning.
    1. Structural Biology and Molecular Biophysics

    SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path

    Masataka Yamauchi, Giovanni Bruno Brandani ... Shoji Takada
    An asymmetric kleisin path breaks the symmetry of the SMC homodimer, ensuring unidirectional DNA translocation via a segment capture mechanism.