Highlights

  • The ins and outs of breathing

    Subpopulations of neurons in the pre-Bötzinger complex coordinate breathing with a range of physiological behaviors.

    Mariana R Melo, Alexander D Wykes ... Andrew M Allen
    Research Article Updated
  • How V. cholerae senses bile

    A complex called ToxRS is central to the mechanism by which bile acids cause Vibrio cholerae to become virulent.

    Nina Gubensäk, Theo Sagmeister ... Tea Pavkov-Keller
    Research Article Updated
  • Memory and multiple sclerosis

    A new approach to measuring visual working memory has revealed fresh insights into the origins of memory deficit in multiple sclerosis. (Photo: Pouria Motaghi CC-BY)

    Ali Motahharynia, Ahmad Pourmohammadi ... Mehdi Sanayei
    Research Article

Latest research

    1. Epidemiology and Global Health
    2. Medicine

    Association between bisphosphonate use and COVID-19 related outcomes

    Jeffrey Thompson, Yidi Wang ... Ulrich H von Andrian
    A claims-based retrospective cohort study shows that patients who used bisphosphonates between 01/01/2019 and 02/29/2020 had dramatically reduced odds of SARS-CoV-2 testing, COVID-19 diagnosis, and COVID-19-related hospitalizations during the initial surge of the COVID-19 pandemic in the US.
    1. Developmental Biology

    Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegans

    Taylor N Medwig-Kinney, Brian A Kinney ... David Q Matus
    Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for members of the Groucho/TCF repressive complex in maintaining non-invasive cell fate in C. elegans.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The genomic footprint of social stratification in admixing American populations

    Alex Mas Sandoval, Sara Mathieson, Matteo Fumagalli
    1. Medicine

    A single-cell atlas depicting the cellular and molecular features in human anterior cruciate ligamental degeneration: A single cell combined spatial transcriptomics study

    Runze Yang, Tianhao Xu ... Weili Fu
    Single-cell combined spatial transcriptomics provides the molecular foundation for investigating how ligamental cell identities, biochemical functions, and interactions contributed to the ligamental degeneration process.
    1. Neuroscience

    Two human brain systems micro-structurally associated with obesity

    Manfred G Kitzbichler, Daniel Martins ... Neil A Harrison
    Revealing two distinct brain systems linked to obesity, this research illuminates the intricate relationship between obesity, brain microstructure and genetics with potential implications for treatment and prevention.
    1. Neuroscience

    PAK3 downregulation induces cognitive impairment following cranial irradiation

    Haksoo Lee, Hyunkoo Kang ... BuHyun Youn
    1. Cancer Biology

    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells

    Pirunthan Perampalam, James I. MacDonald ... Frederick A. Dick
    1. Genetics and Genomics

    Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis

    Hao Yu, Anas M. Khanshour ... Carol A. Wise
    1. Epidemiology and Global Health
    2. Medicine

    Pharmacometric assessment of primaquine induced haemolysis in glucose-6-phosphate dehydrogenase deficiency

    Sasithon Pukrittayakamee, Podjanee Jittamala ... Nicholas J White