Latest research

1. 1. Neuroscience

   Poor coherence in older people's speech is explained by impaired semantic and executive processes

   Paul Hoffman et al.

   Remaining focused on the topic at hand when speaking depends on effective selection of task-relevant semantic knowledge, and declines in this ability account for increases in off-topic speech in older people.
2. 1. Neuroscience

   Building a functional connectome of the Drosophila central complex

   Romain Franconville et al.

   The central complex, a highly conserved insect brain region important for navigation, is characterized by a high degree of recurrence and a sparseness of output pathways.
3. 1. Neuroscience

   Adaptation after vastus lateralis denervation in rats demonstrates neural regulation of joint stresses and strains

   Cristiano Alessandro et al.

   The adaptation strategy used by the nervous system following muscle paralysis restores task performance while minimizing the stresses and strains within a joint.
4. 1. Neuroscience

   FluoEM, virtual labeling of axons in three-dimensional electron microscopy data for long-range connectomics

   Florian Drawitsch et al.

   Methodology to annotate the multiple origins of axonal projections in dense electron microscopy data of mammalian nervous tissue without the need of chemical label conversion is reported.
5. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

   Katherine A Smith et al.
6. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke

   Paulo Wagner Pires, Scott Earley
7. 1. Neuroscience

   Causal contribution and dynamical encoding in the striatum during evidence accumulation

   Michael M Yartsev et al.

   Behavioral, pharmacological, optogenetic, electrophysiological and computational analyses suggest that the anterior dorsal striatum is a causal node in the network responsible for evidence accumulation.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   YAP drives cutaneous squamous cell carcinoma formation and progression

   Zoé Vincent-Mistiaen et al.

   High levels of nuclear YAP are sufficient to drive squamous cell carincoma formation and frequently also drive progression to spindle cell carcinoma by promoting epithelial-to-mesenchymal transition after tissue damage.
9. 1. Physics of Living Systems

   Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner

   Feng-Ching Tsai et al.
10. 1. Neuroscience

    Persistent coding of outcome-predictive cue features in the rat nucleus accumbens

    Jimmie M Gmaz et al.