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Latest research

    1. Ecology

    Eco-evolutionary dynamics modulate plant responses to global change depending on plant diversity and species identity

    Peter Dietrich et al.
    Offspring of plants selected at low and high plant diversity differently respond to global change drivers (nitrogen enrichment, drought), as reflected by their biomass production and trait expression, whereby plant-soil interactions play a significant role in these processes.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Rate-limiting transport of positively charged arginine residues through the Sec-machinery is integral to the mechanism of protein secretion

    William J Allen et al.
    The time it takes to secrete a protein is dominated by diffusion of positively charged arginines through the channel across the membrane, but lysines avoid this problem as they are neutralised before transport.
    1. Neuroscience

    Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse

    Amy Richardson et al.
    The Kv3.3 potassium channel subunit is necessary and sufficient to permit presynaptic location and accelerated repolarisation of the presynaptic action potential, thereby conserving resources and enhancing accuracy of timing information on transmission at the calyx of Held excitatory synapse.
    1. Neuroscience

    Drosophila nicotinic acetylcholine receptor subunits and their native interactions with insecticidal peptide toxins

    Dagmara Korona et al.
    Blocking of the function of neurotransmitter receptors by insecticidal peptide toxins resulted in identification of nicotinic acetylcholine receptor subunits through native ligand-binding investigations.
    1. Genetics and Genomics
    2. Neuroscience

    Machine learning sequence prioritization for cell type-specific enhancer design

    Alyssa J Lawler et al.
    A new cross-species machine learning-based strategy is applied to find enhancers that specifically label parvalbumin neurons in the mouse and macaque.