Highlights

We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    RHODOPSIN 7: An ancestral non-canonical photoreceptor shaping light-responsive behavior

    Valentina Kirsch, Nils Reinhard ... Pingkalai R Senthilan
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A novel high-throughput single-cell DNA sequencing method reveals hidden genomic heterogeneity in the unicellular eukaryote Leishmania

    Gabriel H Negreira, Pieter Monsieurs ... Malgorzata A Domagalska
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    D-serine suppresses one-carbon metabolism by competing with mitochondrial L-serine transport

    Masataka Suzuki, Kenichiro Adachi ... Jumpei Sasabe
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Parvalbumin interneuron ErbB4 controls ongoing network oscillations and olfactory behaviours in mice

    Bin Hu, Chi Geng ... Xiao-Yu Hou
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Ultrasound neuromodulation hypotheses on the directionality of effects and community resource

    Hugo Caffaratti, Ben Slater ... Chris Petkov
    An inTUS scientific resource is advanced to support evaluation of how low-intensity transcranial ultrasound can enhance or suppress neural function.
    1. Structural Biology and Molecular Biophysics

    Structural insights into peptidoglycan hydrolysis by the FtsEX system in Escherichia coli during cell division

    Jianwei Li, Yutong He ... Min Luo
    Structural and biochemical analyses reveal how E. coli FtsEX accommodates EnvC asymmetry to regulate amidase activation during bacterial cell division.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Out-of-balance growth enables cost-free synthesis of the flagellum and other proteins in a single bacterium

    Mayra Patricia Garcia Alcala, Josiah C Kratz, Philippe Cluzel
    Surprisingly, monitoring single bacteria expressing constitutive or flagellar genes reveals faster growth, a benefit driven by inherited, cost-free growth factors, whereas bulk measurements show an expected net fitness cost.
    1. Neuroscience

    Loose coupling between Ca2+ channels and release sensors as a synaptic correlate of higher-order brain function

    Grit Bornschein, Max Schwarze ... Hartmut Schmidt
    Identical pyramidal neuron synapses use distinct presynaptic calcium influx-transmitter release coupling architectures in prefrontal and primary somatosensory cortices, shaping synaptic properties to support area-specific cortical functions.
    1. Ecology
    2. Genetics and Genomics

    Plasticity associated with adoption of social roles in clown anemonefish

    Lili F Vizer, Douglas Alvarado ... Pete Buston
    During the establishment of size-based dominance hierarchies in clown anemonefish, an individual's social context shapes its growth trajectory through coordinated changes in feeding behavior, aggressive behaviors, and gene expression.
    1. Biochemistry and Chemical Biology

    Cell cycle-coupled CK1δ turnover, autoinhibition, and activity

    Fidel Emmanuel Serrano, Bianca Ruppert ... Michael Brunner
    In light of recent observations of how CK1δ is dynamically regulated, kinase activity and abundance are also regulated throughout the cell cycle primarily through phosphorylation at the C-terminal tail.
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Magazine

    1. Epidemiology and Global Health

    Science Forum: The new paradox of women’s health research

    Ursula Debarnot, Alexandre Fouré
    1. Genetics and Genomics
    2. Physiology

    Steroid Signaling: A hormonal message for a longer life

    Kyle Feola, Peter M Douglas
    1. Microbiology and Infectious Disease

    Bird Flu: The cow udder as an influenza mixing ground

    Silke Rimaux, Robert P de Vries
    1. Computational and Systems Biology

    AI in Science: The 42 problem in AI-assisted research

    Giovanni Spitale, Federico Germani
    1. Genetics and Genomics
    2. Developmental Biology
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    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

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  6. Research Culture: From East to West – an early-career researcher’s voyage across continents

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  7. Close-up of an iris

    Episode 105: September 2026

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Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
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  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
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  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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