Highlights

  • Replication in Drosophila studies

    An analysis of 400 articles on the immune response in Drosophila highlights a need for caution regarding the replicability of certain claims.

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Reviewed Preprint Updated

  • Tsetse fly feeding adaptations

    Investigations into the biomechanics of tsetse fly blood feeding reveal that subtle anatomical adaptations enable the penetration of a diverse range of host hides.

    Stephan Löwe, Laura Hauf ... Markus Engstler
    Research Article

  • Anatomy of taste and texture

    Comprehensive ultrastructural reconstruction of the Drosophila larval pharyngeal sensory system reveals the organization and diversity of its sensory structures.

    Vincent Richter, Tilman Triphan ... Andreas S Thum
    Research Article

  • Neurosecretory connections

    Connectomic and transcriptomic analyses reveal the anatomical and functional organisation of neurosecretion in the Drosophila brain.

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Research Article

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Explore our new collection

    Delve into leading research on Lifestyle, Environment and Epigenetic Inheritance.

    Collection
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Cell Biology
    2. Developmental Biology

    Dynamin 2–dependent endocytosis differentially regulates ligand and receptor contributions to Notch signaling during neural precursor cell fate determination

    Joshua J Breunig, Jon I Arellano ... Pasko Rakic
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Chromosomes and Gene Expression

    KMT2A modulates the epigenetic landscape of rDNA by facilitating the recruitment of histone lysine acetyltransferase PCAF to the rDNA locus

    Kaisar Ahmad Lone, Anita Choudhary ... Shweta Tyagi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Integrin-dependent trafficking of CD98hc reduces endocytic noise to maintain metabolic homeostasis

    F Sila Rizalar, Hans Peter Grimm ... Roberto Villaseñor
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Computational and Systems Biology

    High-dimensional Characterization of Genome–Environment Fitness Landscapes in Klebsiella pneumoniae

    Ge Zhou, Georgia Williams ... Danesh Moradigaravand
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Plant Biology

    Multi-omic integration using interpretable machine learning reveals genetic mechanisms of trait variation and phenotypic plasticity in switchgrass

    Paulo Izquierdo, Xiaoyu Weng ... Shin-Han Shiu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Simple methods to acutely measure multiple timing metrics among the sexual repertoire of male Drosophila

    Yutong Song, Hongyu Miao ... Woo Jae Kim
    DrosoMating is a streamlined software and open-hardware platform that automates high-throughput temporal profiling of male Drosophila courtship and mating behaviors with high accuracy.
    1. Neuroscience

    Expectation-driven gain modulation of preparatory spatial attention

    Dirk van Moorselaar, Stefan van der Stigchel
    Expectations about visual search difficulty enhance processing at attended locations by strengthening attentional signals rather than narrowing the spatial focus of attention.
    1. Genetics and Genomics
    2. Neuroscience

    The hypoxic response extends lifespan through a bioaminergic and peptidergic neural circuit

    Elizabeth S Kitto, Shijiao Huang ... Scott F Leiser
    Genetic induction of the hypoxic response promotes longevity through a cell-nonautonomous neuronal to intestinal circuit governed by serotonin, tyramine/adrenaline, GABA, and neuropeptide signaling.
    1. Evolutionary Biology

    Large inversions in Lake Malawi cichlids are associated with habitat, lineage, and sex determination

    Nikesh M Kumar, Taylor L Cooper ... Patrick T McGrath
    Structural variants acquired through ancient hybridization can supply the raw material for ecological divergence while providing the recombination-suppressed background in which sex determination systems operate.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Kinesin-1 holoenzyme assembly coordinates cargo-adaptor recognition with heavy-chain autoinhibition

    Jingling Niu, Mengmeng Zhang ... Chao Wang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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Magazine

    1. Cell Biology
    2. Physiology

    Mechanosensory Physiology: Lymphatic vessels under pressure

    Asser F Bedair, Osama F Harraz
    1. Epidemiology and Global Health

    Science Forum: The new paradox of women’s health research

    Ursula Debarnot, Alexandre Fouré
    1. Genetics and Genomics
    2. Physiology

    Steroid Signaling: A hormonal message for a longer life

    Kyle Feola, Peter M Douglas
    1. Microbiology and Infectious Disease

    Bird Flu: The cow udder as an influenza mixing ground

    Silke Rimaux, Robert P de Vries
    1. Computational and Systems Biology

    AI in Science: The 42 problem in AI-assisted research

    Giovanni Spitale, Federico Germani
    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan

  7. Research Culture: From East to West – an early-career researcher’s voyage across continents

    Samuel C Eziuzor
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
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  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
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  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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