Ketone diet helps suppress mutant phenotype in worms

Latest research

1. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells

   Nathaniel Paul Meyer, Tania Singh ... Diane L Barber

   Clonal naïve human embryonic stem cells assemble an Arp2/3 complex-dependent contractile actin filament ring around colonies that promotes tensional forces favoring cell-cell adhesion and nuclear translocation of YAP to maintain ground-state pluripotency.
2. 1. Cell Biology

   Time-resolved proximity proteomics uncovers a membrane tension-sensitive caveolin-1 interactome at the rear of migrating cells

   Eleanor Martin, Rossana Girardello ... Alexander Ludwig

   Membrane tension controls the dynamic assembly and disassembly of caveolae and their association with the F-actin cortex in migrating cells.
3. 1. Cell Biology
   2. Developmental Biology

   Limited column formation in the embryonic growth plate implies divergent growth mechanisms during pre- and postnatal bone development

   Sarah Rubin, Ankit Agrawal ... Elazar Zelzer

   Modulation of division plane rotation in proliferating chondrocytes determines the ratio of clusters and columns, which may support the multifunctional design of the growth plate.
4. 1. Cancer Biology
   2. Evolutionary Biology

   The theory of massively repeated evolution and full identifications of Cancer Driving Nucleotides (CDNs)

   Lingjie Zhang, Tong Deng ... Chung-I Wu
5. 1. Physics of Living Systems

   Information gain at the onset of habituation to repeated stimuli

   Giorgio Nicoletti, Matteo Bruzzone ... Daniel Maria Busiello
6. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   SIV-specific neutralizing antibody induction following selection of a PI3K drive-attenuated nef variant

   Hiroyuki Yamamoto, Tetsuro Matano
7. 1. Microbiology and Infectious Disease
   2. Computational and Systems Biology

   Lipid discovery enabled by sequence statistics and machine learning

   Priya M Christensen, Jonathan Martin ... Kelli L Palmer
8. 1. Neuroscience

   The dominance of global phase dynamics in human cortex, from delta to gamma

   David M Alexander, Laura Dugué
9. 1. Biochemistry and Chemical Biology

   SLC35G1: A highly chloride-sensitive transporter responsible for the basolateral membrane transport in intestinal citrate absorption

   Yoshihisa Mimura, Tomoya Yasujima ... Hiroaki Yuasa
10. 1. Neuroscience

    Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits

    Yaroslav I Molkov, Anke Borgmann ... Jeffrey C Smith