Highlights

  • Vocal learning in bats

    Maternal behavior influences vocal development and learning in the neotropical bat species Saccopteryx bilineata. Photo credit: Michael Stifter.

    Ahana A Fernandez, Nora Serve ... Mirjam Knörnschild
    Reviewed Preprint Updated
  • Exploring vascular disease

    Interactions between fibroblast cells and smooth muscle cells have a central role in the development of pulmonary hypertension.

    Slaven Crnkovic, Helene Thekkekara Puthenparampil ... Grazyna Kwapiszewska
    Research Article
  • Looking at lens development

    A study in mice reveals key interactions between the proteins involved in fibroblast growth factor (FGF) signaling and how they contribute to distinct stages of eye lens development.

    Qian Wang, Hongge Li ... Xin Zhang
    Reviewed Preprint Updated

Latest research

    1. Microbiology and Infectious Disease

    Secretory leukocyte protease inhibitor influences periarticular joint inflammation in B. burgdorferi-infected mice

    Qian Yu, Xiaotian Tang ... Erol Fikrig
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia

    Nguyet Le, Sherine Awad ... Seth Blackshaw
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Rhythmic circuit function is more robust to changes in synaptic than intrinsic conductances

    Zachary Fournier, Leandro M Alonso, Eve Marder
    Modifications of the intrinsic currents in neuronal circuits are more likely to result in loss of function than changes in synaptic strength.
    1. Developmental Biology

    The epididymis contributes to sperm DNA integrity and early embryo development through Cysteine-Rich Secretory Proteins

    Valeria Sulzyk, Ludmila Curci ... Patricia S Cuasnicu
    The identification of epididymal proteins relevant for sperm DNA integrity and early embryo development will contribute to a better understanding, diagnosis, and treatment of human infertility.
    1. Immunology and Inflammation

    Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice

    Mohsen Khosravi-Maharlooei, Andrea Vecchione ... Megan Sykes
    Functional analyses identify Tfh-like and Tph-like CD4+ T cells as drivers of a spontaneous autoimmune syndrome characterized by autoreactive B cells in human immune system mice.
    1. Developmental Biology
    2. Neuroscience

    In mice, discrete odors can selectively promote the neurogenesis of sensory neuron subtypes that they stimulate

    Kawsar Hossain, Madeline Smith ... Stephen W Santoro
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    DeePosit: an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments

    David Peles, Shai Netser ... Shlomo Wagner
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Medicine
    2. Neuroscience

    mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

    Philip Stavrides, Chris N Goulbourne ... Dun-Sheng Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Cholecystokinin modulates age-dependent Thalamocortical Neuroplasticity

    Xiao Li, Jingyu Feng ... Jufang He
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology
    2. Cell Biology

    Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications

    Ida Marie Boisen, Nadia Krarup Knudsen ... Martin Blomberg Jensen
    Testicular microcalcifications arise secondary to local alterations in mineral homeostasis, which in combination with impaired Sertoli cell function and reduced levels of mineralization inhibitors facilitate deposition of hydroxyapatite.