Highlights

  • Measures of consciousness

    The methods used to assess whether stimuli are ‘seen’ (conscious) or ‘unseen’ (unconscious) have an impact of neural measures of consciousness. Image: Matthew Willis (CC BY 4.0).

    Johannes J Fahrenfort, Philippa A Johnson ... Simon van Gaal
    Reviewed Preprint Updated
  • Exploring vascular disease

    Interactions between fibroblast cells and smooth muscle cells have a central role in the development of pulmonary hypertension.

    Slaven Crnkovic, Helene Thekkekara Puthenparampil ... Grazyna Kwapiszewska
    Research Article
  • Looking at lens development

    A study in mice reveals key interactions between the proteins involved in fibroblast growth factor (FGF) signaling and how they contribute to distinct stages of eye lens development.

    Qian Wang, Hongge Li ... Xin Zhang
    Reviewed Preprint Updated

Latest research

    1. Cell Biology
    2. Developmental Biology

    Transcriptome profiling of tendon fibroblasts at the onset of embryonic muscle contraction reveals novel force-responsive genes

    Pavan K Nayak, Arul Subramanian, Thomas F Schilling
    Muscle contraction forces shape tenocyte gene expression, with sequencing and spatial analyses revealing unique force-dependent gene regulation patterns, suggesting tenocytes fine-tune tendon matrix in response to varied mechanical cues.
    1. Genetics and Genomics
    2. Medicine

    EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis

    Lianlei Wang, Xinyu Yang ... Nan Wu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani

    Supratim Pradhan, Dhruba Dhar ... Budhaditya Mukherjee
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Neural substrates of cold nociception in Drosophila larva

    Atit A Patel, Albert Cardona, Daniel N Cox
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    A multiplex of connectome trajectories enables several connectivity patterns in parallel

    Parham Mostame, Jonathan Wirsich ... Sepideh Sadaghiani
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling

    Rachel Nakagawa, Andrew Beardsley ... Andrei Goga
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    A toolbox for ablating excitatory and inhibitory synapses

    Aida Bareghamyan, Changfeng Deng ... Don B Arnold
    Novel genetically encoded tools PFE3, paGFE3, and chGFE3 can be used to reversibly ablate excitatory synapses constitutively, and inhibitory synapses in a light- or chemically dependent manner.
    1. Ecology

    A circadian clock drives behavioral activity in Antarctic krill (Euphausia superba) and provides a potential mechanism for seasonal timing

    Lukas Hüppe, Dominik Bahlburg ... Bettina Meyer
    Behavioral experiments provide strong evidence that krill swimming behavior is controlled by biological clocks throughout the year, revealing a key mechanism for adaptation to high-latitude habitats.
    1. Neuroscience

    Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair

    Patricia E Phelps, Sung Min Ha ... Xia Yang
    To better understand how olfactory ensheathing cells modify spinal cord injury sites, single-cell RNA-sequencing was used to identify five OEC subtypes, progenitors, and novel genes associated with axonal outgrowth.