Highlights

  • From disorder to stability

    An intrinsically disordered region in a scaffolding protein called Zasp52 is required to stabilize Z-discs in the indirect flight muscle in Drosophila.

    Nikolai Ho, Frieder Schöck
    Reviewed Preprint

  • Context-dependent behavior

    A region of the brain called the retrosplenial cortex has an important role in integrating contextual information and sensory stimuli in mice.

    Pol Bech, Robin F Dard ... Carl CH Petersen
    Reviewed Preprint Updated

  • Seeing movement

    Inhibitory feedback from GABAergic interneurons C2 and C3 is tied to neural computation of moving visual stimuli in Drosophila.

    Miriam Henning, Madhura D Ketkar ... Marion Silies
    Research Article

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article

  • How to respond to peer reviewers

    Responding to peer reviews is a crucial part of publishing, but early-career researchers are rarely taught about it.

    Eric Kalkhoven, Manon Kluijtmans
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Cancer Biology

    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis

    Patrick B Jonker, Mumina Sadullozoda ... Alexander Muir
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Physics of Living Systems

    The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

    Robbert van der Pijl, Jochen Gohlke ... Coen Ottenheijm
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology
    2. Neuroscience

    ARHGEF6-dependent cytoskeletal regulation underlies a conserved program of forebrain interneuron development

    Carla Liaci, Beatrice Savarese ... Giorgio R Merlo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Modality-Specific and Amodal Language Processing by Single Neurons

    Yair Lakretz, Naama Friedmann ... Itzhak Fried
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Arousal modulates functional connectivity through structured and hemispherically asymmetric community architecture during wakefulness

    Xiangyu Kong, Siyu Li, Gaolang Gong
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cancer Biology
    2. Physics of Living Systems

    Heterotypic interfacial tension between oncogenic and wild-type populations forms the mechanical basis of tissue-specific oncogenesis in epithelia

    Amrapali Datta, Phanindra Dewan ... Medhavi Vishwakarma
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis

    Peter Georgiev, Sheila Johnson ... Arlene H Sharpe
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Divergent spatiotemporal integration of whole-field visual motion in medaka and zebrafish larvae

    Yasuko Isoe, Yasmine Fatima Mabene ... Florian Engert
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Intron Retention Controls Localization of lncRNAs PURPL and MALAT1 to Promote Cell Proliferation and Migration

    Ioannis Grammatikakis, Chosita Norkaew ... Ashish Lal
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    • Compelling
    1. Cell Biology
    2. Neuroscience

    A validated antibody toolbox for ALS research

    Riham Ayoubi, Emma J MacDougall ... Carl Laflamme
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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Magazine

    1. Neuroscience

    Verbal Memory: Language acquisition in newborns

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  2. Episode 103: May 2026

    1. Neuroscience

    Visual Perception: Insights into perceptual learning

    Zhong-Lin Lu
    1. Neuroscience

    Neuroendocrinology: Surging towards a better understanding of ovulation

    Lillian Rose, Alexander S Kauffman
    1. Cell Biology
    2. Neuroscience

    Auditory Hair Cells: Examining the role of lipids in hearing

    Yein Christina Park, Angela Ballesteros

  6. Point of View: Science under threat around the world

    Humberto J Debat
    1. Biochemistry and Chemical Biology

    Lipid Transport: How membranes shape up for lipid transfer

    Takashi Hirashima, Toshiya Endo
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
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