Highlights

Latest research

    1. Neuroscience

    AVN: A Deep Learning Approach for the Analysis of Birdsong

    Therese MI Koch, Ethan S Marks, Todd F Roberts
    1. Genetics and Genomics

    Dysfunction of Calcyphosine-Like gene impairs retinal angiogenesis through the MYC axis and is associated with familial exudative vitreoretinopathy

    Wenjing Liu, Shujin Li ... Xianjun Zhu
    Genetic analysis and knockout mouse model study identified calcyphosine-like (CAPSL) as a candidate disease gene in familial exudative vitreoretinopathy (FEVR), offering valuable insights into disease mechanisms.
    1. Cell Biology
    2. Immunology and Inflammation

    S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi

    Daniel M Williams, Andrew A Peden
    Recruitment of NLRP3 to the Golgi is controlled by the reversible addition of a lipid anchor adjacent to the polybasic region.
    1. Ecology

    Fine-scale tracking reveals visual field use for predator detection and escape in collective foraging of pigeon flocks

    Mathilde Delacoux, Fumihiro Kano
    Foveal vision in pigeons plays a crucial role in predator detection while the flock is collectively foraging and being vigilant.
    1. Evolutionary Biology

    Improved inference of population histories by integrating genomic and epigenomic data

    Thibaut Sellinger, Frank Johannes, Aurélien Tellier
    The developed statistical method paves the way for next generation demographic and selection inference by combining information from several heritable genomic and epigenomic markers.
    1. Neuroscience

    Altered firing output of VIP interneurons and early dysfunctions in CA1 hippocampal circuits in the 3xTg mouse model of Alzheimer’s disease

    Felix Michaud, Ruggiero Francavilla ... Lisa Topolnik
    Early alterations in VIP interneuron activity may contribute to disruptions in CA1 hippocampal circuits and cognitive deficits in the 3xTg mouse model of Alzheimer's disease.
    1. Cell Biology
    2. Neuroscience

    Upregulated expression of ubiquitin ligase TRIM21 promotes PKM2 nuclear translocation and astrocyte activation in experimental autoimmune encephalomyelitis

    Luting Yang, Chunqing Hu ... Yaping Yan
    Cell biology and animal model analysis in mice shows that molecules involved in glycolytic metabolism could potentially serve as therapeutic targets for the treatment of neurological diseases.
    1. Neuroscience

    Sensory-memory interactions via modular structure explain errors in visual working memory

    Jun Yang, Hanqi Zhang, Sukbin Lim
    1. Neuroscience

    POMC neurons control fertility through differential signaling of MC4R in Kisspeptin neurons

    Rajae Talbi, Todd L Stincic ... Víctor M Navarro