Highlights

Latest research

    1. Neuroscience

    Distinct cortical encoding of acoustic and electrical cochlear stimulation

    Ariel Edward Hight, Michele N Insanally ... Robert C Froemke
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression

    Linking Germline Telomere Removal to Global Programmed DNA Elimination in Tetrahymena Genome Differentiation

    Kohei Nagao, Alix Lemoine ... Kazufumi Mochizuki
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Cancer Biology

    DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma

    Simar Pal Singh, Kumar Mangalam ... Annemiek B van Spriel
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into the recruitment of viral type 2 IRES to ribosomal preinitiation complex for protein synthesis

    Deepakash Das, Tanweer Hussain
    The viral type 2 internal ribosome entry site uses a unique mechanism to hijack the host ribosomal machinery by interacting with initiator tRNA and 40S head.
    1. Developmental Biology

    A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivatives

    Rotem Leshem, Syed Murtuza-Baker ... Nicoletta Bobola
    Transcriptomic profiling of the developing human outflow tract and adult aortic valves reveals that adult valve cells retain distinct embryonic molecular signatures.
    1. Physics of Living Systems

    Controlling the synchronization and symmetry breaking of coupled bacterial pili on active biofilm carpets

    Baha Altın, Enes Talha Günay ... Askin Kocabas
    Active biofilm carpets generate Mexican-wave-like synchronized dynamics and topological defects through nonreciprocal pili interactions.
    1. Neuroscience

    Intrinsic properties link a network model to zebra finch song

    Nelson D Medina, Dan Margoliash
    Whole-cell recordings paired with a network model show that post-inhibitory rebound excitation in premotor neurons couples intrinsic excitability to the temporal structure of learned birdsong.
    1. Neuroscience

    SynaptoTagMe, a toolkit for in vivo mapping and modulating neurotransmission at single-cell resolution

    Andrea Cuentas-Condori, Patricia Chanabá-López ... Daniel A Colón-Ramos
    Endogenous tagging and conditional silencing of vesicular transporters reveal widespread, conserved co-transmission, and enable causal dissection of transmitter-specific synaptic function, linking molecular identity to circuit dynamics and behavior in vivo.
    1. Microbiology and Infectious Disease

    Mycobacterium tuberculosis partitions the Krebs cycle under iron starvation

    Agnese Serafini, Acely Garza-Garcia ... Riccardo Manganelli
    Mycobacterium tuberculosis rewires central carbon metabolism to circumvent iron-dependent metabolic routes during iron starvation.
    1. Cell Biology

    PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progression

    Jimena Druker, Hao Jiang ... Angus I Lamond
    Proline hydroxylation of RepoMan (CDCA2) at P604 by PHD1 is shown to be important for mitotic progression and regulating interaction with PP2A regulatory subunit B56 gamma.