Highlights

  • Evolutionary interplay

    The evolutionary history of a family of beetles called Belidae has been influenced by the breakup of the supercontinent Gondwana and the rise of angiosperms.

    Xuankun Li, Adriana E Marvaldi ... Duane D McKenna
    Research Article
  • eLife in 2024

    Looking back at some of the key milestones and announcements of the past year.

    Inside eLife
  • Bone repair in aged mice

    A combination of intermittent fasting and Wnt3a proteins administered via a bandage can rejuvenate bone repair.

    Joshua Reeves, Pierre Tournier ... Shukry J Habib
    Research Article

Latest research

    1. Cell Biology

    Hypersensitive intercellular responses of endometrial stromal cells drive invasion in endometriosis

    Chun-Wei Chen, Jeffery B Chavez ... Bruce J Nicholson
    A unique functional comparison of the major endometrial cell types from 44 control and endometriosis patients demonstrates not only a uterine origin of the disease, but also that endometrial to mesothelial cell gap junctions are required for invasive lesion formation.
    1. Neuroscience

    Deficiency of Orexin Receptor Type 1 in Dopaminergic Neurons Increases Novelty-Induced Locomotion and Exploration

    Xing Xiao, Gagik Yeghiazaryan ... A Christine Hausen
    Revised
    Reviewed Preprint v3
    Updated
    1. Genetics and Genomics
    2. Evolutionary Biology

    The Primate Major Histocompatibility Complex: An Illustrative Example of Gene Family Evolution

    Alyssa Lyn Fortier, Jonathan K Pritchard
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Humans adapt rationally to approximate estimates of uncertainty

    Erdem Pulcu, Michael Browning
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Canonical neurodevelopmental trajectories of structural and functional manifolds

    Alicja Monaghan, Richard. AI Bethlehem ... Duncan E Astle
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Sex-specific behavioral and thalamo-accumbal circuit adaptations after oxycodone abstinence

    Yanaira Alonso-Caraballo, Yan Li ... Elena H Chartoff
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Geometry and dynamics of representations in a precisely balanced memory network related to olfactory cortex

    Claire Meissner-Bernard, Friedemann Zenke, Rainer W Friedrich
    Computational modeling revealed that balanced assemblies of excitatory and inhibitory neurons shape representational manifolds in olfactory cortex-like recurrent networks, resulting in joint maps of sensory and semantic information.
    1. Neuroscience

    Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG

    Cristina Gil Avila, Elisabeth S May ... Markus Ploner
    Multiverse analysis of the aperiodic component of the electroencephalography (EEG) power spectrum yielded robust evidence against a relationship to chronic pain, guiding further research on EEG biomarkers of chronic pain.
    1. Computational and Systems Biology

    AI-driven automated discovery tools reveal diverse behavioral competencies of biological networks

    Mayalen Etcheverry, Clément Moulin-Frier ... Michael Levin
    A novel methodology, using diversity search AI algorithms, for exploring the space of possible behaviors of gene regulatory networks, from the perspective of generic problem-solving agents navigating their environment.