All research categories

Highlights

  • Deep mutational scanning

    High-resolution approach has been used to assess the effect of more than 6000 protein-coding variants in a G protein-coupled receptor associated with obesity.

    Conor J Howard, Nathan S Abell ... Nathan B Lubock
    Reviewed Preprint Updated

  • Cell mechanics and metastasis

    The discovery of a pro-invasive mechanotransduction pathway driven by cell crowding suggests that an ion channel called TRPV4 may be a promising therapeutic target for inhibiting metastasis.

    Xiangning Bu, Nathanael Ashby ... Inhee Chung
    Reviewed Preprint Updated

  • Social behaviors in mice

    A cell atlas for the preoptic area of the brain could be used to investigate how neuronal traits may be evolving to give rise to innate differences in social behavior across species.

    Jenny Chen, Phoebe R Richardson ... Hopi E Hoekstra
    Reviewed Preprint Updated

Latest research

    1. Neuroscience

    Visual routines for detecting causal interactions are tuned to motion direction

    Sven Ohl, Martin Rolfs
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience
    2. Physics of Living Systems

    The Geometry and Dimensionality of Brain-wide Activity

    Zezhen Wang, Weihao Mai ... Quan Wen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine

    Early menarche and childbirth accelerate aging-related outcomes and age-related diseases: Evidence for antagonistic pleiotropy in humans

    Yifan Xiang, Vineeta Tanwar ... Pankaj Kapahi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Progressively shifting patterns of co-modulation among premotor cortex neurons carry dynamically similar signals during action execution and observation

    Zhonghao Zhao, Marc H Schieber
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Untangling stability and gain modulation in cortical circuits with multiple interneuron classes

    Hannah Bos, Christoph Miehl ... Brent Doiron
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    Load-based divergence in the dynamic allostery of two TCRs recognizing the same pMHC

    Ana C Chang-Gonzalez, Aoi Akitsu ... Wonmuk Hwang
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Evolutionary Biology

    Pronounced expression of extracellular matrix proteoglycans regulated by Wnt pathway underlies the parallel evolution of lip hypertrophy in East African cichlids

    Nagatoshi Machii, Ryo Hatashima ... Masato Nikaido
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Ecology

    Loss of olfaction reduces caterpillar performance and increases susceptibility to a natural enemy

    Qi Wang, Yufei Jia ... Alexander Haverkamp
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    A multiomic study reveals the role of ZFHX3 transcription factor in daily timekeeping with a combination of transcription factor and histone ChIP-seq and time-resolved RNA-seq in the mammalian central clock.
    1. Neuroscience

    The neural correlates of novelty and variability in human decision-making under an active inference framework

    Shuo Zhang, Yan Tian ... Haiyan Wu
    Neurobehavioral data combined with computational models shows the superiority of active inference models in explaining human decisions under uncertainty.
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Magazine

    1. Neuroscience

    Hippocampus: Mapping out overlapping connectivity patterns

    Myrthe Faber, Koen V Haak
    1. Cell Biology
    2. Developmental Biology

    Ovarian Biology: Revisiting the rete ovarii

    Yan Zhang, Hua Zhang
    1. Microbiology and Infectious Disease

    Viruses: How herpes is assembled

    Dawid S Zyla
    1. Neuroscience

    Metabolism: Insulin control in fruit flies

    Omowumi Kayode
  5. Anne Urai and Clare Kelly (CC BY 4.0)

    Activism and Science: Anne Urai and Clare Kelly on responding to the climate and biodiversity crises

    1. Developmental Biology
    2. Genetics and Genomics

    Vascular Development: Enhancing our understanding of endothelial cells

    Guillermo Luxán
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Cellular Energy Production: Mycofactocin and the mycobacterial electron transport chain

    Stephanie M Stuteley, Ghader Bashiri
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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