Latest research

1. 1. Developmental Biology
   2. Neuroscience

   Presynaptic developmental plasticity allows robust sparse wiring of the Drosophila mushroom body

   Najia A Elkahlah et al.

   Sensory innervation density in the insect associative learning center is set by postsynaptic cells and accomplished by flexible allocation of processes by presynaptic cells.
2. 1. Biochemistry and Chemical Biology

   Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription

   Sarah K Stumper et al.

   Single-molecule observations reveal a mechanism that may be used by multiple competing regulatory proteins to control ribosomal RNA production during rapid bacterial cell growth.
3. 1. Cell Biology
   2. Neuroscience

   Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

   Junjun Zhao et al.

   Two homologous kinesin motors, KIF5A and KIF5B, have distinct functions in dendritic spine morphogenesis, and KIF5B plays a role in synaptic plasticity and memory.
4. 1. Cell Biology
   2. Neuroscience

   TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons

   Emily Bowie, Sarah C Goetz

   Signaling at the primary cilium is important to sustain the morphology, connectivity, and survival of a key neural population within the brain.
5. 1. Cell Biology

   Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes

   Natalia Wesolowska et al.

   Combined light and electron microscopy reveals a new function for Arp2/3-mediated actin assembly in nuclear envelope rupture, which leads to a separation of nuclear membranes and pores from the lamina.
6. 1. Ecology

   Genomic adaptations in information processing underpin trophic strategy in a whole-ecosystem nutrient enrichment experiment

   Jordan G Okie et al.

   Trait-based metagenomic analysis of an ecosystem fertilization experiment shows that genomic traits that affect the costs and rates of biochemical information-processing mediate community assembly.
7. 1. Neuroscience
   2. Structural Biology and Molecular Biophysics

   Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain

   Tianyu Wang et al.

   Quantitative experiments and analysis determine the limit of excitation power of 1300-nm three-photon microscopy, and the imaging depth where three-photon outperforms two-photon for calcium imaging in the mouse brain.
8. 1. Neuroscience

   Social structure learning in human anterior insula

   Tatiana Lau et al.
9. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols

   Vayu Maini Rekdal et al.

   A previously unrecognized group of metalloenzymes enables human gut microbes to metabolize dietary molecules and neurotransmitters and likely mediates interactions and metabolism among environmental microorganisms.
10. 1. Neuroscience

    A Toll-receptor map underlies structural brain plasticity

    Guiyi Li et al.