Latest research

1. 1. Cell Biology

   H⁺- and Na⁺- elicited rapid changes of the microtubule cytoskeleton in the biflagellated green alga Chlamydomonas

   Yi Liu et al.

   Acidification and salt, which are two major stresses caused by environmental changes, swiftly and drastically alter the microtubule system in green algae and likely many other organisms.
2. 1. Neuroscience

   A quantitative theory of gamma synchronization in macaque V1

   Eric Lowet et al.

   Gamma-band synchronization behavior in area V1 was predicted by weakly coupled oscillator principles.
3. 1. Biophysics and Structural Biology

   Asymmetry of movements in CFTR's two ATP sites during pore opening serves their distinct functions

   Ben Sorum et al.
4. 1. Developmental Biology and Stem Cells

   Essential role for SUN5 in anchoring sperm head to the tail

   Yongliang Shang et al.
5. 1. Neuroscience

   Two-photon calcium imaging of the medial prefrontal cortex and hippocampus without cortical invasion

   Masashi Kondo et al.
6. 1. Neuroscience

   Signal integration at spherical bushy cells enhances representation of temporal structure but limits its range

   Christian Keine et al.
7. 1. Cell Biology

   Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe

   Nicholas R Guydosh et al.
8. 1. Neuroscience

   A double-sided microscope to realize whole-ganglion imaging of membrane potential in the medicinal leech

   Yusuke Tomina, Daniel A Wagenaar
9. 1. Cell Biology
   2. Genes and Chromosomes

   Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast

   Wahid A Mulla et al.

   Genetic analyses reveal that purely quantitative changes in the relative copy number of chromosomes can be sufficient to disrupt the epigenetic mechanisms that define the cells' differentiated state.
10. 1. Computational and Systems Biology
    2. Developmental Biology and Stem Cells

    A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning

    Qixuan Wang et al.

    Regional differences in activator and inhibitor signals alter hair cycle pace across mouse skin and produce unique fur renewal 'landscapes', with fastest renewal on the ventrum and slowest renewal on the ear pinnae.