Highlights

We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Developmental Biology

    Gcn5 and mTORC1 mediated regulation of autophagy controls Drosophila blood cell homeostasis

    Arjun Aji Reeja, Mincy Kunjumon ... Rohan Jayant Khadilkar
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    A Spatiotemporal Hierarchy for Social Interaction Perception in the Lateral Visual Stream

    Emalie McMahon, Elizabeth Jiwon Im ... Leyla Isik
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Hierarchical Neural Circuit Theory of Normalization and Inter-areal Communication

    Asit Pal, Shivang Rawat ... Stefano Martiniani
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Ecology
    2. Plant Biology

    Genetic canalization of nutrient resorption in the widespread grass Phragmites australis under salt stress

    Lele Liu, Wenyi Sheng ... Weihua Guo
    Salinity does not alter nutrient resorption efficiency, which is instead shaped by phylogeographic history and latitude.
    1. Cell Biology

    Small brown planthopper infestation enhances it reproduction and insecticide tolerance by manipulating glucose distribution and levels in rice

    Hainan Zhang, Qi Zhang ... Jianjun Wang
    Small brown planthopper infestation drives rice glucose redistribution to boost its own reproduction and insecticide tolerance.
    1. Neuroscience

    The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cells

    Tanay Ghosh, Roey Baror ... Robin JM Franklin
    gSWITCH identifies dynamic lineage switch genes and reveals BCL11A as an evolutionarily conserved regulator whose restoration rescues age-impaired oligodendrocyte progenitor cell differentiation.
    1. Biochemistry and Chemical Biology

    SARS-CoV-2 main protease inhibition through dimerization promotion by peptidomimetic inhibitors and disruption by ebselen

    Chengxi Liu, Qinyu Jia ... Zhong-Ping Yao
    Distinct effects of peptidomimetic inhibitors and ebselen on SARS-CoV-2 main protease dimerization reveal new strategies for antiviral drug design.
    1. Structural Biology and Molecular Biophysics

    Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching

    Kexin Zhang, Timothy Grant, Nikolaus Grigorieff
    High-resolution structural information can be recovered from proteins well below the conventional cryo-electron microscopy size range, substantially extending the range of complexes accessible to structural analysis.
    1. Developmental Biology
    2. Neuroscience

    Heterogeneous responses to embryonic critical period perturbations within the Drosophila larval locomotor circuit

    Niklas Krick, Jacob J Davies ... Matthias Landgraf
    Within the locomotor network of the Drosophila embryo, connected elements, from premotor interneuron to muscle, respond differentially to a critical period perturbation, suggesting a sequence of adjustment.
    1. Medicine

    Mid-zone hepatocytes trade proliferation for survival via Atf4-Chop axis in early acute liver injury

    Yaying Zhu, Chengxiang Deng ... Zhao Shan
    Mid-zone hepatocytes transiently pause proliferation through the Atf4-Chop-Btg2 axis to prioritize survival over regeneration during early acute liver injury.
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Magazine

    1. Epidemiology and Global Health

    Science Forum: The new paradox of women’s health research

    Ursula Debarnot, Alexandre Fouré
    1. Genetics and Genomics
    2. Physiology

    Steroid Signaling: A hormonal message for a longer life

    Kyle Feola, Peter M Douglas
    1. Microbiology and Infectious Disease

    Bird Flu: The cow udder as an influenza mixing ground

    Silke Rimaux, Robert P de Vries
    1. Computational and Systems Biology

    AI in Science: The 42 problem in AI-assisted research

    Giovanni Spitale, Federico Germani
    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan

  6. Research Culture: From East to West – an early-career researcher’s voyage across continents

    Samuel C Eziuzor
  7. Close-up of an iris

    Episode 105: September 2026

  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
  17. Plant Biology
  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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