Latest research

1. 1. Neuroscience

   7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

   Hideaki Tomita, Kelly M Hines ... Libin Xu

   A 7-dehydrocholesterol-derived oxysterol in SLOS was found to profoundly impact neurogenesis during cortical development by interacting with glucocorticoid receptor, which points to new therapeutic approaches for SLOS by targeting the activities of this oxysterol.
2. 1. Developmental Biology

   A neurogenic signature involving monoamine Oxidase-A controls human thermogenic adipose tissue development

   Javier Solivan-Rivera, Zinger Yang Loureiro ... Silvia Corvera

   A hybrid mouse/human model using mesenchymal progenitor cells reveals dynamics of human adipose tissue development and mechanisms that may enhance human adipose thermogenic capacity.
3. 1. Developmental Biology

   Murine blastocysts generated by in vitro fertilization show increased Warburg metabolism and altered lactate production

   Seok Hee Lee, Xiaowei Liu ... Paolo F Rinaudo

   In vitro fertilization-conceived murine embryos show evidence of oxidative and metabolic stress with alteration in lactic acid metabolism.
4. 1. Neuroscience

   Distinct population and single-neuron selectivity for executive and episodic processing in human dorsal posterior cingulate

   Lyndsey Aponik-Gremillion, Yvonne Y Chen ... Brett L Foster

   Invasive recordings from human dorsal posterior cingulate cortex show neural population responses occur for only executive tasks, while single neuron responses occur for specific executive or episodic cognitive tasks.
5. 1. Cell Biology

   Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1

   Meng Zhao, Niels Banhos Dannieskiold-Samsøe ... Katrin J Svensson
6. 1. Chromosomes and Gene Expression

   The SPARC complex defines RNAPII promoters in Trypanosoma brucei

   Desislava P Staneva, Stefan Bresson ... Robin C Allshire
7. 1. Neuroscience

   Flexing the principal gradient of the cerebral cortex to suit changing semantic task demands

   Zhiyao Gao, Li Zheng ... Elizabeth Jefferies
8. 1. Neuroscience

   Functional gradients in the human lateral prefrontal cortex revealed by a comprehensive coordinate-based meta-analysis

   Majd Abdallah, Gaston E Zanitti ... Demian Wassermann
9. 1. Developmental Biology
   2. Neuroscience

   A dynamic and expandable Digital 3D-Atlas MAKER for monitoring the temporal changes in tissue growth during hindbrain morphogenesis

   Matthias Blanc, Giovanni Dalmasso ... Cristina Pujades
10. 1. Developmental Biology
    2. Neuroscience

    Plexins promote hedgehog signaling through their cytoplasmic GAP activity

    Justine M Pinskey, Tyler M Hoard ... Benjamin L Allen