Latest research

1. 1. Neuroscience

   Male pheromones modulate synaptic transmission at the C. elegans neuromuscular junction in a sexually dimorphic manner

   Kang-Ying Qian et al.

   Male pheromone environment increases the cholinergic synaptic transmission at the neuromuscular junction in Caenorhabditis elegans hermaphrodites during development, decreasing hermaphrodites' locomotion activity and promoting mating efficiency.
2. 1. Developmental Biology

   Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic diseases in mice

   Georges Raad et al.

   Predisposition to obesity-associated diseases is dependent on the ancestors' diet.
3. 1. Evolutionary Biology

   Striking parallels between dorsoventral patterning in Drosophila and Gryllus reveal a complex evolutionary history behind a model gene regulatory network

   Matthias Pechmann et al.

   Crucial functions of Toll signalling during dorsoventral axis formation might have evolved convergently in flies and crickets.
4. 1. Immunology and Inflammation
   2. Neuroscience

   Development and characterization of a chronic implant mouse model for vagus nerve stimulation

   Ibrahim T Mughrabi et al.

   Long-term, dose-controlled vagus nerve stimulation (VNS) is feasible in mice using a multi-lab validated implantation procedure, allowing therapeutic testing of VNS in many disease models.
5. 1. Neuroscience

   Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex

   Shinya Ohara et al.

   The connection from layer Vb-to-Va neurons, a key component of the canonical hippocampal-cortical output circuit, which is allegedly crucial for memory consolidation, is relatively stronger in lateral entorhinal cortex compared with the medial entorhinal cortex, thus suggesting different operating principles.
6. 1. Neuroscience

   Slowing the body slows down time perception

   Rose De Kock et al.

   The perception of time is influenced by movement environments, with slower movements associated with shorter perceived time intervals.
7. 1. Microbiology and Infectious Disease

   Functional insights from a surface antigen mRNA-bound proteome

   Larissa Melo do Nascimento et al.

   A robust procedure to purify mRNAs and their associated proteins identify CFB2 as the critical protein that binds and influences the fate of the main virulence factor in Trypanosoma brucei.
8. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

   Emma Carley et al.

   Forces stemming from cell-matrix adhesions, but not cell-cell adhesions, are directly transmitted to the nuclear lamina to regulate epidermal cell fate.
9. 1. Neuroscience

   A visual pathway for skylight polarization processing in Drosophila

   Ben J Hardcastle et al.

   Circuit tracing and in vivo calcium imaging reveals neurons conveying polarized light information from photoreceptors to the central brain, transforming patterns in the sky into a directional cue for navigation.
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

    Thomas J Etheridge et al.