Highlights

  • Replication in Drosophila studies

    An analysis of 400 articles on the immune response in Drosophila highlights a need for caution regarding the replicability of certain claims.

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Reviewed Preprint Updated

  • Tsetse fly feeding adaptations

    Investigations into the biomechanics of tsetse fly blood feeding reveal that subtle anatomical adaptations enable the penetration of a diverse range of host hides.

    Stephan Löwe, Laura Hauf ... Markus Engstler
    Research Article

  • Anatomy of taste and texture

    Comprehensive ultrastructural reconstruction of the Drosophila larval pharyngeal sensory system reveals the organization and diversity of its sensory structures.

    Vincent Richter, Tilman Triphan ... Andreas S Thum
    Research Article

  • Neurosecretory connections

    Connectomic and transcriptomic analyses reveal the anatomical and functional organisation of neurosecretion in the Drosophila brain.

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Research Article

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Explore our new collection

    Delve into leading research on Lifestyle, Environment and Epigenetic Inheritance.

    Collection
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    Specific Sensitivity to Rare and Extreme Events: Quasi-Complete Black Swan Avoidance vs Partial Jackpot Seeking in Rat Decision-Making

    Mickaël Degoulet, Louis-Matis Willem ... Patrick A Pintus
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    NAD boosting mediated by CD38 inhibition drives reversal of a pathological vicious cycle of intracrine activity and inflammation in eyelid meibomian gland dysfunction

    Yuki Hamada, Takehide Sakamoto ... Masao Doi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology

    Chromatin priming and Hunchback recruitment integrate spatial and temporal cues in Drosophila neuroblasts

    Ayanthi Bhattacharya, Hemalatha Rao, Sonia Q Sen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    Human giant GTPase GVIN1 forms an antimicrobial coatomer around the intracellular bacterial pathogen Burkholderia thailandensis

    Weilun Guo, Shruti S Apte ... Jörn Coers
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Microbiology and Infectious Disease

    Virus-specific impacts on honey bee flight performance are mediated by the octopamine pathway

    Naomi G Kaku, Michelle L Flenniken
    Differential virus-specific impacts on honey bee flight performance involve octopamine signaling, and chemical stressors affecting this pathway may impact colony health.
    1. Neuroscience

    Dual-feature selectivity enables bidirectional coding in visual cortical neurons

    Nikos Karantzas, Katrin Franke ... Andreas Savas Tolias
    Many visual cortical neurons are excited by one feature and suppressed by another, encoding stimuli bidirectionally around an elevated baseline in macaques and mice.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The nuclear membrane protein Samp1 links peripheral genome organization to the myogenic transcriptional program

    Urška Kašnik, Irene Mei ... Einar Hallberg
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Single-Molecule Nanopore Profiling of p53-TAD’s Conformational Dynamics, Interactions, and Inhibition

    David DeCoeur, Samantha Schultz ... Min Chen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Compelling
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Dynamin 2–dependent endocytosis differentially regulates ligand and receptor contributions to Notch signaling during neural precursor cell fate determination

    Joshua J Breunig, Jon I Arellano ... Pasko Rakic
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Chromosomes and Gene Expression

    KMT2A modulates the epigenetic landscape of rDNA by facilitating the recruitment of histone lysine acetyltransferase PCAF to the rDNA locus

    Kaisar Ahmad Lone, Anita Choudhary ... Shweta Tyagi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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Magazine

    1. Cell Biology
    2. Physiology

    Mechanosensory Physiology: Lymphatic vessels under pressure

    Asser F Bedair, Osama F Harraz
    1. Epidemiology and Global Health

    Science Forum: The new paradox of women’s health research

    Ursula Debarnot, Alexandre Fouré
    1. Genetics and Genomics
    2. Physiology

    Steroid Signaling: A hormonal message for a longer life

    Kyle Feola, Peter M Douglas
    1. Microbiology and Infectious Disease

    Bird Flu: The cow udder as an influenza mixing ground

    Silke Rimaux, Robert P de Vries
    1. Computational and Systems Biology

    AI in Science: The 42 problem in AI-assisted research

    Giovanni Spitale, Federico Germani
    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan

  7. Research Culture: From East to West – an early-career researcher’s voyage across continents

    Samuel C Eziuzor
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
  17. Plant Biology
  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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