Latest research

1. 1. Developmental Biology
   2. Genetics and Genomics

   An atlas of cell types in the mouse epididymis and vas deferens

   Vera D Rinaldi et al.

   A systematic survey of the epididymis identifies the cell types involved in post-testicular maturation of sperm.
2. 1. Structural Biology and Molecular Biophysics

   Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations

   Tone Bengtsen et al.

   Molecular simulations, small-angle X-ray and neutron scattering experiments and previously measured NMR experiments were combined to study the structure and dynamics of the proteins and lipids in a nanodisc.
3. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution

   Bishnu P Paudel et al.

   Human telomerase unfolds and extends parallel G-quadruplexes using a unique mechanism involving its RNA template.
4. 1. Computational and Systems Biology
   2. Neuroscience

   A unified computational model for cortical post-synaptic plasticity

   Tuomo Mäki-Marttunen et al.

   Biochemically detailed modelling of pathways leading to post-synaptic plasticity reveals the dependence of neocortical LTP/LTD on the availability of different proteins and stimulation patterns.
5. 1. Epidemiology and Global Health

   Early analysis of the Australian COVID-19 epidemic

   David J Price et al.
6. 1. Evolutionary Biology

   Plasticity and evolutionary convergence in the locomotor skeleton of Greater Antillean Anolis lizards

   Nathalie Feiner et al.
7. 1. Evolutionary Biology
   2. Genetics and Genomics

   Atypical meiosis can be adaptive in outcrossed Schizosaccharomyces pombe due to wtf meiotic drivers

   María Angélica Bravo Núñez et al.

   The wtf meiotic drivers change the fitness landscape of meiosis in outcrossed Schizosaccharomyces pombe demonstrating that genetic parasites can favor the evolution of variants that disrupt meiotic fidelity.
8. 1. Computational and Systems Biology
   2. Developmental Biology

   A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

   Bjoern Gaertner et al.

   Ribosome profiling and loss-of-function during human ESC pancreatic differentiation reveal abundant lncRNA translation and an essential role for translated LINC00261 in beta cell differentiation, likely through a trans-regulatory, microprotein-independent mechanism.
9. 1. Neuroscience

   Tuning of olfactory cortex ventral tenia tecta neurons to distinct task elements of goal-directed behavior

   Kazuki Shiotani et al.

   Individual neurons of ventral tenia tecta which is a part of olfactory cortex tune to specific time windows in the behavioral context during odor-guided goal-directed behaviors.
10. 1. Developmental Biology
    2. Medicine

    RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1

    Md Rakibul Hasan et al.

    RAB23 regulates calvarial bone and suture development both independently through, and by cross-talk between, Hedgehog and fibroblast growth factor signaling.