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Highlights

  • Cylicins and male fertility

    Mutations in the genes for two cytoskeletal proteins found in sperm, Cylicin 1 and Cylicin 2, can lead to infertility in mice and humans.

    Simon Schneider, Andjela Kovacevic ... Hubert Schorle
    Research Article

  • The ins and outs of breathing

    Subpopulations of neurons in the pre-Bötzinger complex coordinate breathing with a range of physiological behaviors.

    Mariana R Melo, Alexander D Wykes ... Andrew M Allen
    Research Article Updated

  • Memory and multiple sclerosis

    A new approach to measuring visual working memory has revealed fresh insights into the origins of memory deficit in multiple sclerosis. (Photo: Pouria Motaghi CC-BY)

    Ali Motahharynia, Ahmad Pourmohammadi ... Mehdi Sanayei
    Research Article

Latest research

    1. Evolutionary Biology
    2. Genetics and Genomics

    Down the Penrose stairs, or how selection for fewer recombination hotspots maintains their existence

    Zachary Baker, Molly Przeworski, Guy Sella
    Modeling the evolution of PRDM9 in light of recent results implicating the importance of PRDM9 binding symmetry suggests the advantage of new PRMD9 alleles is in limiting the number of binding sites used effectively rather than increasing net binding.
    1. Neuroscience

    Modeling apical and basal tree contribution to orientation selectivity in a mouse primary visual cortex layer 2/3 pyramidal cell

    Konstantinos-Evangelos Petousakis, Ji Young Park ... Panayiota Poirazi
    1. Immunology and Inflammation

    Pulsed ultrasound promotes secretion of anti-inflammatory extracellular vesicles from skeletal myotubes via elevation of intracellular calcium level

    Atomu Yamaguchi, Noriaki Maeshige ... Hidemi Fujino
    Ultrasound promotes release of extracellular vesicles from cultured myotubes and elicits anti-inflammatory effects on macrophages, indicating the potential of ultrasound stimulation to muscle for anti-inflammatory purposes.
    1. Physics of Living Systems

    A unified approach to dissecting biphasic responses in cell signalling

    Vaidhiswaran Ramesh, J Krishnan
    1. Immunology and Inflammation

    G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs

    Yi-Hong Li, Yi-Sen Yang ... Liquan Huang
    1. Cell Biology
    2. Immunology and Inflammation

    DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

    Fabian Hersperger, Tim Meyring ... Katrin Kierdorf
    1. Developmental Biology

    FMNL2 regulates actin for ER and mitochondria distribution in oocyte meiosis

    Meng-Hao Pan, Zhen-Nan Pan ... Shao-Chen Sun
    1. Cancer Biology
    2. Cell Biology

    mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3IBTK-mediated non-degradative ubiquitination of eIF4A1

    Huiru Sun, Dongyue Jiao ... Chenji Wang
    1. Neuroscience

    Haplotype Function Score improves biological interpretation and cross-ancestry polygenic prediction of human complex traits

    Weichen Song, Yongyong Shi, Guan Ning Lin
    1. Neuroscience

    Systemic pharmacological suppression of neural activity reverses learning impairment in a mouse model of Fragile X syndrome

    Amin Md Shakhawat, Jacqueline G Foltz ... Jennifer L Raymond
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Magazine

  1. Albatrosses at sea

    Episode 90: December 2023

  2. A cartoonish human figure sitting on the outline of a brain on a light brown background with a bright white spark. Vicky Bowskill (CC BY-NC-ND 4.0)

    Being Neurodivergent in Academia: How to navigate fieldwork

    Hella Péter
    1. Epidemiology and Global Health

    Sleep: Another benefit of regular sleep

    Tianyi Huang
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Transcription: A hub of activity

    Virginia L Pimmett, Mounia Lagha
    1. Cell Biology

    Trans-Golgi Network: Sorting secretory proteins

    Anup Parchure, Julia von Blume

  6. Meta-Research: The changing career paths of PhDs and postdocs trained at EMBL

    Junyan Lu, Britta Velten ... Rachel Coulthard-Graf
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Antibody Specificity: A strong case for third-party testing

    Fridtjof Lund-Johansen
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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