Highlights

  • Evolutionary interplay

    The evolutionary history of a family of beetles called Belidae has been influenced by the breakup of the supercontinent Gondwana and the rise of angiosperms.

    Xuankun Li, Adriana E Marvaldi ... Duane D McKenna
    Research Article
  • Targeting a methyltransferase

    The SARS-CoV-2 main protease targets an enzyme called TRMT1 that modifies transfer RNA.

    Angel D'Oliviera, Xuhang Dai ... Jeffrey S Mugridge
    Research Article
  • eLife’s new Editor-in-Chief

    Timothy Behrens has been appointed Editor-in-Chief to lead our efforts to improve research communication for all.

    Press Pack

Latest research

    1. Biochemistry and Chemical Biology

    Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

    Gabriella O Estevam, Edmond M Linossi ... James S Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    DIO-SPOTlight Transgenic Mouse to Functionally Monitor Protein Synthesis Regulated by the Integrated Stress Response

    Matthew L Oliver, Zachary F Caffall ... Nicole Calakos
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Plant Biology
    2. Ecology

    Strip cropping designed for maintaining productivity increases ground beetle biodiversity

    Luuk Croijmans, Fogelina Cuperus ... Erik H Poelman
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology

    Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process

    Ke Ning, Yuanyuan Xie ... Ling Yu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics
    2. Evolutionary Biology

    Inversions Can Accumulate Balanced Sexual Antagonism: Evidence from Simulations and Drosophila Experiments

    Christopher S McAllester, John E Pool
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter

    Parveen Goyal, KanagaVijayan Dhanabalan ... Subramanian Ramaswamy
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Ecology

    A circadian clock drives behavioral activity in Antarctic krill (Euphausia superba) and provides a potential mechanism for seasonal timing

    Lukas Hüppe, Dominik Bahlburg ... Bettina Meyer
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Computational and Systems Biology
    2. Physics of Living Systems

    How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective

    Joseph Ackermann, Chiara Bernard ... Martine Ben Amar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing