Latest research

1. 1. Ecology
   2. Plant Biology

   Genetic variation, environment and demography intersect to shape Arabidopsis defense metabolite variation across Europe

   Ella Katz et al.

   Measurements of specialized metabolites across a population of 800 natural Arabidopsis thaliana accessions revealed different pressures and evolutionary processes that shaped their variation and distribution across Europe.
2. 1. Evolutionary Biology

   Myoglobin primary structure reveals multiple convergent transitions to semi-aquatic life in the world's smallest mammalian divers

   Kai He et al.

   Ancestral sequence reconstruction of an essential muscle protein involved in O₂ storage and transport accurately tracks secondary aquatic transitions in a speciose clade of insectivorous mammals.
3. 1. Computational and Systems Biology
   2. Developmental Biology

   Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration

   Emanuel Cura Costa et al.

   Computational modeling and a cell cycle-reporting axolotl reveal how spinal cord regeneration can be achieved by a signal that propagates 828 μm from the injury site during the first 85 hours post-amputation.
4. 1. Genetics and Genomics

   Establishment of H3K9me3-dependent heterochromatin during embryogenesis in Drosophila miranda

   Kevin H-C Wei et al.
5. 1. Microbiology and Infectious Disease
   2. Plant Biology

   Biosynthesis of a sulfated exopolysaccharide, synechan, and bloom formation in the model cyanobacterium Synechocystis sp. strain PCC 6803

   Kaisei Maeda et al.

   A potentially useful cyanobacterial sulfated exopolysaccharide and its biosynthesis and regulation genes, which contribute to the laboratorial bloom formation, are elucidated for the first time among prokaryotes.
6. 1. Cell Biology
   2. Neuroscience

   The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia

   Katalin Skrapits et al.
7. 1. Neuroscience

   The temporal representation of experience in subjective mood

   Hanna Keren et al.
8. 1. Genetics and Genomics
   2. Medicine

   Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning

   Yi Liu et al.

   Systematic quantification of abdominal organ health parameters using deep learning generates new insights into the genetic architecture of cardiometabolic health traits.
9. 1. Cell Biology
   2. Medicine

   Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ

   Yang Zhang et al.

   Identifying xanthohumol and its derivatives as PPARγ anatagonists provides new insight into how natural compounds beneficially treat obesity and metabolic syndrome, and provide new compounds for therapeutic development.
10. 1. Biochemistry and Chemical Biology

    Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA

    M'Lynn E Fisher et al.

    Activation of the sarcoplasmic reticulum calcium pump and enhancement of cellular calcium homeostasis by dwarf open reading frame reveal how this small membrane protein opposes phospholamban inhibitory function in cardiac muscle.