Highlights

  • The ins and outs of breathing

    Subpopulations of neurons in the pre-Bötzinger complex coordinate breathing with a range of physiological behaviors.

    Mariana R Melo, Alexander D Wykes ... Andrew M Allen
    Research Article Updated
  • How V. cholerae senses bile

    A complex called ToxRS is central to the mechanism by which bile acids cause Vibrio cholerae to become virulent.

    Nina Gubensäk, Theo Sagmeister ... Tea Pavkov-Keller
    Research Article Updated
  • Memory and multiple sclerosis

    A new approach to measuring visual working memory has revealed fresh insights into the origins of memory deficit in multiple sclerosis. (Photo: Pouria Motaghi CC-BY)

    Ali Motahharynia, Ahmad Pourmohammadi ... Mehdi Sanayei
    Research Article

Latest research

    1. Microbiology and Infectious Disease

    Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein

    Qibin Geng, Yushun Wan ... Fang Li
    Lys417 regulates the opening and closing of SARS-CoV-2 spike protein, allowing SARS-CoV-2 to maintain a delicate balance between infectiousness and evading host immune response.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance

    Rebecca EK Mandt, Madeline R Luth ... Amanda K Lukens
    The mutational flexibility of the antimalarial target dihydroorotate dehydrogenase thwarts the use of collateral sensitivity as a strategy to suppress the evolution of resistance.
    1. Genetics and Genomics
    2. Medicine

    Type I fiber decrease and ectopic fat accumulation in skeletal muscle from women with PCOS

    E Stener-Victorin, G Eriksson ... A Benrick
    1. Physics of Living Systems

    Universal length fluctuations of actin structures found in cells

    Aldric Rosario, Shane G. McInally ... Jane Kondev
    1. Computational and Systems Biology

    Detection of new pioneer transcription factors as cell-type specific nucleosome binders

    Yunhui Peng, Wei Song ... Anna R. Panchenko