Highlights

  • Evolutionary interplay

    The evolutionary history of a family of beetles called Belidae has been influenced by the breakup of the supercontinent Gondwana and the rise of angiosperms.

    Xuankun Li, Adriana E Marvaldi ... Duane D McKenna
    Research Article
  • eLife in 2024

    Looking back at some of the key milestones and announcements of the past year.

    Inside eLife
  • Plasticity and performance

    A mechanism linking the plasticity of a dopaminergic circuit and behavioural performance has been observed in Drosophila.

    Jun Sun, Francisca Rojo-Cortes ... Alicia Hidalgo
    Research Article

Latest research

    1. Neuroscience

    Input-specific gating of NMDA amplification via HCN channels in mouse L2/3 pyramidal neurons

    Viktor János Oláh, Jing Wu ... Matthew JM Rowan
    Revised
    Reviewed Preprint v2
    Updated
    1. Cell Biology

    Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

    Joan Chang, Adam Pickard ... Karl E Kadler
    Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in fibrotic fibroblasts.
    1. Neuroscience

    Complementary cognitive roles for D2-MSNs and D1-MSNs during interval timing

    Robert A Bruce, Matthew Weber ... Kumar Narayanan
    Dorsomedial D2-MSNs and D1-MSNs exhibit opposing dynamics during interval timing, however disrupting either MSN type produces similar effects on behavior, highlighting the complementary roles of striatal pathways in cognitive operations.
    1. Epidemiology and Global Health

    Leveraging mobility data to analyze persistent SARS-CoV-2 mutations and inform targeted genomic surveillance

    Riccardo Spott, Mathias W Pletz ... Christian Brandt
    Integrating mobile service and fine-granular sample data enhances SARS-CoV-2 genomic surveillance, improving variant tracking, optimizing efficiency, and guiding targeted sampling strategies.
    1. Genetics and Genomics

    3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

    Khanh B Trang, Matthew C Pahl ... Struan FA Grant
    Integration of GWAS summary statistics with extensive 3D genomic datasets generated in a myriad of different cell types provides genomic insights into pediatric obesity pathogenesis.
    1. Neuroscience

    Statistical learning beyond words in human neonates

    Ana Fló, Lucas Benjamin ... Ghislaine Dehaene-Lambertz
    Revised
    Reviewed Preprint v2
    Updated