Highlights

  • Closing the neural tube

    High-throughput arrayed CRISPR interference screening of organoid models gives insight into genetic regulators of neural tube closure in humans.

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    Research Article

  • Mechanics of oncogenesis

    Integrative mechanobiological approaches provide insight into the biophysics of tissue-specific tumor growth.

    Amrapali Datta, Phanindra Dewan ... Medhavi Vishwakarma
    Research Article

  • Pikas power yak pastures

    Plateau pikas play a role in enhancing weight gains in yaks, by suppressing toxic plants and improving the availability and quality of palatable forage.

    Zhiwei Zhong, Bingbo Ni ... Zhibin Zhang
    Reviewed Preprint Updated

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    Axially decoupled photo-stimulation and two photon readout (ADePT) for mapping functional connectivity of neural circuits

    Matthew Koh, Francesca Anselmi ... Dinu F Albeanu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Temporal constraints on the neural signatures of narrative processing

    Aline-Priscillia Messi, Abir Bhuyain, Liina Pylkkanen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Distance Mapping and Variable-Specific Geometry of Goal-Relevant Frames in the Retrosplenial Cortex

    Yumin Chen, Xinhang Wei ... Haibing Xu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Evolutionary Biology

    Super compensatory substitutions restore protein function and flatten fitness landscapes

    Wenhong Jiang, Hengchuang Yin ... Lucas B Carey
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Whole brain mapping of spinal-projecting neurons in larval zebrafish

    Martin Carbo-Tano, Kevin Fidelin ... Claire Wyart
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Computational and Systems Biology

    Protein generation with evolutionary diffusion: sequence is all you need

    Sarah Alamdari, Nitya Thakkar ... Kevin K Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    High basal autophagic activity in the brain revealed by systemic quantitative analysis using GFP-LC3-RFP mice

    Yuki Kanda, Tomoya Eguchi ... Noboru Mizushima
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Polo-like kinase phosphorylation of the orphan kinesin KIN-G negatively regulates centrin arm biogenesis in Trypanosoma brucei

    Yasuhiro Kurasawa, Qing Zhou ... Ziyin Li
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Starvation transforms signal encoding in C. elegans thermoresponsive neurons and suppresses heat avoidance via bidirectional glutamatergic and peptidergic signaling

    Saurabh Thapliyal, Parvathi Sushama Gopinath, Dominique A Glauser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Olfactory combinatorial coding supports risk-reward decision making in C. elegans

    Md Zubayer Hossain Saad, William G Ryan ... Bruce A Bamber
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
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Magazine

  1. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
    1. Cell Biology

    Stress: How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Epidemiology and Global Health

    Malaria Prevention: Using mathematical models to optimise mosquito net distribution

    Carlos A Prete Jr
    1. Plant Biology

    Mixotrophy: An updated view of glucose pathways in cyanobacteria

    José Manuel García-Fernández
  6. Mountain gorilla

    Episode 104: July 2026

    1. Cell Biology
    2. Developmental Biology

    Organ Development: Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
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  4. Chromosomes and Gene Expression
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  12. Medicine
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