Latest research

1. 1. Neuroscience

   RIM is essential for stimulated but not spontaneous somatodendritic dopamine release in the midbrain

   Brooks G Robinson et al.

   Midbrain dopamine neurons use sophisticated secretory machinery to establish specialized sites for action potential-evoked release of dopamine from their cell bodies and dendrites.
2. 1. Developmental Biology
   2. Genetics and Genomics

   Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network

   Yamila N Torres Cleuren et al.

   Quantitative genetic analyses reveal remarkably broad genetic variation underlies the requirement for two critical regulatory inputs into a core embryonic gene regulatory network within one animal species.
3. 1. Developmental Biology
   2. Neuroscience

   How prolonged expression of Hunchback, a temporal transcription factor, re-wires locomotor circuits

   Julia L Meng et al.

   In vivo stem cell reprogramming in the well-studied stem cell NB7-1 using the classic temporal transcription factor Hunchback increases motor neuron number and re-specifies dendritic morphology and neuromuscular synaptic partnerships.
4. 1. Cell Biology
   2. Computational and Systems Biology

   Remote control of microtubule plus-end dynamics and function from the minus-end

   Xiuzhen Chen et al.

   A mechanism for yeast centrosomes to differentiate the microtubule cytoskeleton.
5. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing

   Carlos Gorbea et al.
6. 1. Developmental Biology
   2. Evolutionary Biology

   Fgf-signaling is compartmentalized within the mesenchyme and controls proliferation during salamander limb development

   Sruthi Purushothaman et al.

   While movement of Fgf-signaling to the limb mesenchyme accompanied a shift in function, the ultimate outcome remains a convergent tetrapod limb phenotype.
7. 1. Evolutionary Biology

   Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes

   Wen Xu et al.

   Gene sharing through different isoforms can precede the formation of independent genes.
8. 1. Plant Biology

   Proximity labeling of protein complexes and cell type-specific organellar proteomes in Arabidopsis enabled by TurboID

   Andrea Mair et al.
9. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   A distinct transition from cell growth to physiological homeostasis in the tendon

   Mor Grinstein et al.
10. 1. Neuroscience

    ON selectivity in Drosophila vision is a multisynaptic process involving both glutamatergic and GABAergic inhibition

    Sebastian Molina-Obando et al.