Magazine

Latest articles

1. Scientific Publishing: Progress and promise

   Randy Schekman

   As he prepares to step down as the Editor-in-Chief of eLife, Randy Schekman reflects on the origins of the journal, the eLife approach to peer review, and current challenges in scientific publishing.
2. 1. Evolutionary Biology
   2. Structural Biology and Molecular Biophysics

   Protein Evolution: Building bigger beta-barrels

   Vikas Nanda

   The range of barrel-shaped proteins found in the outer membrane of certain bacteria evolved through multiple pathways.
3. 1. Structural Biology and Molecular Biophysics

   Ion Channels: Solving a specificity mystery

   Sanduo Zheng, Andrew C Kruse

   Differences in the kinetics of G protein activation can explain why only some receptors can activate potassium ion channels called GIRKs.
4. 1. Cancer Biology

   Breast Cancer: Targeting mutant estrogen receptors

   Suzanne E Wardell et al.

   A drug used in hormone replacement therapy can target estrogen receptors that have become resistant to breast cancer treatments.
5. 

   Global Science: Get grants or perish

   Despite the limited range of grants available in Russia, the careers of many researchers depend on this funding.
6. 1. Microbiology and Infectious Disease

   Carboxysomes: How bacteria arrange their organelles

   Emilia Mauriello

   The structures responsible for photosynthesis in bacteria use the nucleoid and two unique proteins as a scaffold to position themselves.
7. 1. Human Biology and Medicine

   Meta-Research: Why we need to report more than 'Data were Analyzed by t-tests or ANOVA'

   Tracey L Weissgerber et al.

   Many papers in basic biomedical science do not contain the information that is needed to determine what statistical tests were used and to verify the results of these tests.
8. 1. Ecology
   2. Evolutionary Biology

   The Natural History of Model Organisms: Nothobranchius furzeri, an 'instant' fish from an ephemeral habitat

   Martin Reichard, Matej Polačik

   The turquoise killifish from ephemeral pools in African savannah combines extremely short lifespan with a standard vertebrate body plan – ideal attributes for a laboratory animal.
9. 1. Neuroscience

   Sexual Differentiation: A matter of timing

   Michael W Perry, Claude Desplan

   A genetic pathway involved in development works together with the sex-determination pathway to control the timing of sexually dimorphic neural development in C. elegans.
10. 1. Evolutionary Biology
    2. Neuroscience

    Glutamate Receptors: Family matters

    Mark L Mayer, Timothy Jegla

    Genome sequence data from a range of animal species are raising questions about the origins of glutamate receptors.