Magazine

Latest articles

1. 1. Neuroscience

   Pain: Revisiting the role of Substance P and CGRPα

   Weihua Cai, Arkady Khoutorsky

   Mice lacking two neuropeptides thought to be essential for processing pain show no change in how they respond to a wide range of harmful stimuli.
2. 1. Genetics and Genomics
   2. Neuroscience

   Neuronal Signaling: Cell-specific tools for understanding behavior

   Brandon L Holder, Stephane Dissel

   Novel tools that allow neuron-specific investigations of the structure controlling sleep regulation in fruit flies reveal the extent of neuronal heterogeneity.
3. 1. Cell Biology
   2. Medicine

   Pulmonary Hypertension: When cell teamwork turns toxic

   Wadih EI Khoury, Stephen Y Chan

   In pulmonary hypertension, a combination of metabolic and mechanical dysfunction leads to irreversible vascular damage.

4. Equity, Diversity and Inclusion: Improving gender equity in academia depends on the workplace environment

   Sreetama Bhadra, Gabriella Damasceno ... Alexandra Weyrich

   The authors recommend actions that can be taken by individuals, institutions and policymakers to promote gender equity.
5. 1. Neuroscience

   Neuronal Signaling: At the crossroads of calcium signaling, protein synthesis and neuropeptide release

   Jakob Rupert, Dragomir Milovanovic

   By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.
6. 1. Cell Biology
   2. Developmental Biology

   Lens Development: Bringing signaling complexity into focus

   Sarah Y Coomson, Salil A Lachke

   A study in mice reveals key interactions between proteins involved in fibroblast growth factor signaling and how they contribute to distinct stages of eye lens development.
7. 1. Immunology and Inflammation

   Inflammasomes: A tale of two caspases

   Denise M Monack

   Macrophages control intracellular pathogens like Salmonella by using two caspase enzymes at different times during infection.

8. Science Under Threat in the United States: Campaigning for science and scientists

   Adriana Bankston

   A Congressional Science & Technology policy fellow outlines some options available for responding to the blatant attacks on science and the scientific workforce in the US.
9. 1. Neuroscience

   Memory: Integrating past experiences

   Thomas MW Leir, Matthew PH Gardner

   New results help address a longstanding debate regarding which learning strategies allow animals to anticipate negative events based on past associations between sensory stimuli.

10. Science Under Threat in the United States: How to make science more efficient

    Stuart Buck

    DOGE needs to completely rethink its efforts to increase the efficiency of the federal agencies that fund research in the US.