Magazine

Highlighting the latest research and giving a voice to scientists
Illustration by Davide Bonazzi

Highlights

    1. Medicine
    2. Neuroscience

    An alternative to opioids

    Jie Zhang, Jianguo Cheng
    1. Neuroscience

    Beware of hidden noise

    Morgan Fitzgerald, Eena Kosik, Bradley Voytek
    1. Neuroscience

    Dopamine: Making memories

    Francesco Longo
    1. Neuroscience

    Neurons: Preparation pays off

    Mark M Churchland
    1. Biochemistry and Chemical Biology

    Improving immunotherapy

    Luca Unione, Jesús Jiménez-Barbero

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Latest articles

    1. Neuroscience

    Dopamine: Making memories

    Francesco Longo
    The neurotransmitter dopamine helps form long-term memories by increasing the production of proteins through a unique signaling pathway.
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    1. Neuroscience

    Neuroscience: Unveiling hidden sources of noise

    Morgan Fitzgerald, Eena Kosik, Bradley Voytek
    Changes in neural activity thought to reflect brain aging may be partly influenced by age-dependent signals ‘leaking’ from the heart.
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    1. Medicine
    2. Neuroscience

    Pain Management: A promising alternative to opioids

    Jie Zhang, Jianguo Cheng
    A complex extracted from the amniotic membrane in humans reduces post-surgical pain in mice by directly inhibiting pain-sensing neurons.
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    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Reprogramming: A perfect recipe for a corticospinal neuron

    Alfonso Aguilera, Marta Nieto
    A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.
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    1. Neuroscience

    Motor Networks: When preparation pays off

    Mark M Churchland
    Computational principles shed light on why movement is preceded by preparatory activity within the neural networks that control muscles.
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    1. Biochemistry and Chemical Biology

    Immunotherapy: The power lies in the glycans

    Luca Unione, Jesús Jiménez-Barbero
    Glycans play an important role in modulating the interactions between natural killer cells and antibodies to fight pathogens and harmful cells.
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    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Point of View: Teaching troubleshooting skills to graduate students

    Gina Partipilo, Yang Gao ... Benjamin K Keitz
    Pipettes and Problem Solving is an initiative that teaches some of the skills needed to figure out why an experiment is producing unexpected results.
    1. Cell Biology

    Kidney Fibrosis: Lock out SIRT4

    Kaiqiang Zhao, Zhongjun Zhou
    The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
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  1. Two ants walking on a branch in the moonlight

    Episode 94: September 2024

    In this episode, we hear about bacterial vampirism, how ants use moonlight to navigate, spontaneous preterm birth, and the different responses of male and female mice to food restriction.
    1. Medicine

    Point of View: Applied research won’t flourish without basic science

    Jon R Lorsch, Lawrence A Tabak, Monica M Bertagnolli
    Three senior figures at the US National Institutes of Health explain why the agency remains committed to supporting basic science and research.