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Highlighting the latest research and giving a voice to scientists
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Latest articles

    1. Microbiology and Infectious Disease

    Helicase Loading: A back-up mechanism for replication

    Godefroid Charbon, Anders Løbner-Olesen
    A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.
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    1. Neuroscience

    Consciousness: Did you see it?

    Ling Liu
    Cautious reporting choices can artificially enhance how well analyses of brain activity reflect conscious and unconscious experiences, making distinguishing between the two more challenging.
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    1. Cell Biology
    2. Neuroscience

    Vision: A pathway to sight

    Katherine J Wert
    The breakdown of glutamine is an important metabolic pathway for the health and survival of rod photoreceptors within the retina.
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    1. Neuroscience

    Synaptic Plasticity: A new mode of action for unconventional NMDA receptors

    Ikuko Smith
    Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.
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    1. Genetics and Genomics
    2. Neuroscience

    Pain: Epidermal cells and sensory neurons team up

    Jean-Christophe Boivin, Tomoko Ohyama
    Experiments in fruit fly larvae show that epidermal cells can communicate with sensory neurons to drive responses to pain.
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    1. Chromosomes and Gene Expression

    Gene Regulation: Linking O-GlcNAc and intron retention

    John A Hanover
    An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.
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    1. Cell Biology
    2. Developmental Biology

    Cell Signaling: Not all dimers are equal

    Jeet H Patel, Mary C Mullins
    Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.
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    1. Immunology and Inflammation

    Bacterial Clearance: With a little help from T cells

    Troy Burtchett, Neal Hammer
    Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.
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  1. members of the coordinating team for the Brazilian Reproducibility Initiative

    Reproducibility: How replicable is biomedical science in Brazil?

    The results of a project to estimate the reproducibility of research in Brazil have just been published.
  2. Image of the female leafhopper Macrosteles quadrilineatus

    Episode 98: April 2025

    In this episode, we hear about parasites as molecular matchmakers, drug combinations and cancer treatment, chemical defences in poison frogs, the impact of education on brain structure, and what movies can reveal about the organisation of the infant visual system.