Magazine

Highlighting the latest research and giving a voice to scientists
Illustration by Davide Bonazzi

Highlights

    1. Neuroscience

    Reversing opioid overdoses

    Jill R Turner, Jocelyn Martin
    1. Neuroscience

    Chronic pain and memory loss

    Suelen Pereira, Ivan Tomsic ... Mychael V Lourenco
    1. Chromosomes and Gene Expression

    A MagIC approach to cryo-EM

    Carlos Moreno-Yruela, Beat Fierz
    1. Genetics and Genomics

    Otitis media and Down syndrome

    Sedigheh Delmaghani, Aziz El-Amraoui
    1. Cell Biology

    Bone repair in aged mice

    Inês Sequeira
    1. Developmental Biology

    Patterning the neural plate

    Margaret Hines, Elias Oxman ... Irene Zohn

Highlights controls:

Latest articles

    1. Medicine

    Special Issue: Reproductive Health

    Edited by Wei Yan et al.
    Our latest Special Issue showcases research in reproductive biology and medicine.
    1. Developmental Biology

    Special Issue: Reproductive health

    Wei Yan
    The articles in this special issue highlight the diversity and complexity of research into reproductive health, including the need for a better understanding of the fundamental biology of reproduction and for new treatments for a range of reproductive disorders.
    1. Neuroscience

    Opioids: Finding new ways to treat overdoses

    Jill R Turner, Jocelyn Martin
    Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.
    Version of Record
    Insight
    1. Neuroscience

    Pain-Related Memory Impairment: How does chronic pain lead to memory loss?

    Suelen Pereira, Ivan Tomsic ... Mychael V Lourenco
    A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.
    Version of Record
    Insight
    1. Genetics and Genomics

    Down Syndrome: How a gene fuels ear infections

    Sedigheh Delmaghani, Aziz El-Amraoui
    The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.
    Version of Record
    Insight
    1. Chromosomes and Gene Expression

    Cryogenic Electron Microscopy: MagIC beads for scarce macromolecules

    Carlos Moreno-Yruela, Beat Fierz
    Specialized magnetic beads that bind target proteins to a cryogenic electron microscopy grid make it possible to study the structure of protein complexes from dilute samples.
    Version of Record
    Insight
    1. Cell Biology

    Aging: Restoring bone healing potential

    Inês Sequeira
    A combination of intermittent fasting and administering Wnt3a proteins to a bone injury can rejuvenate bone repair in aged mice.
    Version of Record
    Insight
    1. Developmental Biology

    Brain Development: Single cells tell it all

    Margaret Hines, Elias Oxman ... Irene Zohn
    A new single-cell atlas of gene expression provides insights into the patterning of the neural plate of mice.
    Version of Record
    Insight
  1. An isopod, well-adapted to the harsh conditions of arid-lands, crawls on the desert floor in search of leaf litter

    Episode 96: December 2024

    In this episode, we hear about predicting the evolution of influenza viruses, how deserts decompose matter, what worms are revealing about a gene linked to autism, and how mice detect the smell of cats.
    1. Computational and Systems Biology

    Cellular Respiration: Mapping mitochondrial aging

    Alessandro Bitto
    Measuring mitochondrial respiration in frozen tissue samples provides the first comprehensive atlas of how aging affects mitochondrial function in mice.
    Version of Record
    Insight