Magazine

Highlighting the latest research and giving a voice to scientists
Illustration by Davide Bonazzi

Highlights

    1. Neuroscience

    Movement: Planning ahead

    Raeed H Chowdhury
    1. Plant Biology

    Seed germination and salt stress

    Xiaoyan Liang, Caifu Jiang
    1. Neuroscience

    The secrets of rhythm

    Mohini Sengupta
    1. Cell Biology

    Burning questions about axons

    Diána Kaszás, Balázs Enyedi

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Latest articles

    1. Medicine

    Point of View: Applied research won’t flourish without basic science

    Jon R Lorsch, Lawrence A Tabak, Monica M Bertagnolli
    Three senior figures at the US National Institutes of Health explain why the agency remains committed to supporting basic science and research.
    1. Neuroscience

    Status Epilepticus: Stopping runaway seizures with a chill pill

    Gordon F Buchanan
    The neuropeptide neurotensin can reduce status epilepticus and its associated consequences through induction of therapeutic hypothermia when bound to a molecule that can penetrate the blood-brain barrier.
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    1. Neuroscience

    Sequential Movement: Reaching into the future

    Raeed H Chowdhury
    When carrying out a sequence of movements, humans can plan several steps in advance to make the movement smooth.
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    1. Plant Biology

    Seed Germination: Coping with salt stress

    Xiaoyan Liang, Caifu Jiang
    Salt stress delays seed germination in plants by increasing the hydrolysis of arginine-derived urea.
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    1. Neuroscience

    Locomotion: The rhythm is going to get you

    Mohini Sengupta
    Slow and fast movements are controlled by distinct sets of spinal V2a neurons with matching properties and connections.
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    1. Cell Biology

    Sensory Neurons: Addressing burning questions on axon regeneration

    Diána Kaszás, Balázs Enyedi
    Regeneration of sensory axons after a burn injury depends on early keratinocyte responses regulated by the wound microenvironment.
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    1. Cell Biology
    2. Developmental Biology

    Fertilization: Switching on lysosomes

    Deepak Adhikari, John Carroll
    The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.
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    1. Structural Biology and Molecular Biophysics

    Nuclear Receptors: A new mode of inhibition

    Andrew D Huber, Taosheng Chen
    Complementary structural biology approaches reveal how an agonist and a covalent inhibitor simultaneously bind to a nuclear receptor.
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    1. Cell Biology
    2. Immunology and Inflammation

    Science Forum: Antibody characterization is critical to enhance reproducibility in biomedical research

    Richard A Kahn, Harvinder Virk ... Skye Longworth
    There is an ongoing need for researchers and all stakeholders to better understand issues surrounding antibody characterization to improve the quality and reproducibility of research that employs these reagents.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Vaccines: How do adjuvants enhance immune responses?

    Rekha R Rapaka
    By altering which peptide antigens are presented to CD4+ T cells, adjuvants affect the specificity of the immune response.
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