eLife Magazine

Highlighting the latest research and giving a voice to scientists
A touch of generations: grandmother reaching out to grandchild. Image credit: Rod Long (CC0)

A hormonal message for a longer life

The steroid hormone dafachronic acid may carry the effects of reduced mTOR activity between tissues to coordinate metabolism and longevity across the body.

Kyle Feola, Peter M Douglas
Insight

Latest articles

    1. Cell Biology
    2. Physiology

    Mechanosensory Physiology: Lymphatic vessels under pressure

    Asser F Bedair, Osama F Harraz
    Lymphatic vessels beat faster as they fill with fluid through a chain of calcium signaling, though the first pressure sensor remains a mystery.
    Version of Record
    Insight
    1. Epidemiology and Global Health

    Science Forum: The new paradox of women’s health research

    Ursula Debarnot, Alexandre Fouré
    Women’s health research will advance when methodological rigor is matched to the question being asked, so that stronger standards improve evidence without inadvertently making studies involving women harder to conduct.
    1. Genetics and Genomics
    2. Physiology

    Steroid Signaling: A hormonal message for a longer life

    Kyle Feola, Peter M Douglas
    The steroid hormone dafachronic acid may carry the effects of reduced mTOR activity between tissues to coordinate metabolism and longevity across the body.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Bird Flu: The cow udder as an influenza mixing ground

    Silke Rimaux, Robert P de Vries
    Bovine mammary tissue can support infection and replication of diverse influenza A viruses and may provide an environment in which different viral strains can co-infect cells.
    Version of Record
    Insight
    1. Computational and Systems Biology

    AI in Science: The 42 problem in AI-assisted research

    Giovanni Spitale, Federico Germani
    Large language models excel at producing answers, but an answer severed from its question and context may lack meaning.
    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan
    eLife publishes research on the mechanisms and biological significance of environmentally driven epigenetic inheritance.
  1. Research Culture: From East to West – an early-career researcher’s voyage across continents

    Samuel C Eziuzor
    International early-career researchers navigating doctoral training and postdoctoral fellowships face compounding structural precarity at every stage but also accumulate a distinctive professional toolkit that institutions on both sides are poorly equipped to recognise or support.
  2. Close-up of an iris

    Episode 105: September 2026

    In this episode, we hear about the origins of our individuality, how synaesthetes' pupil size changes just by thinking of a colour, female chickadees expanding the spectrum of cognitive abilities through non-monogamy, urban wildlife, and the switch to DNA organisation that accompanies cancer.
    1. Cell Biology
    2. Computational and Systems Biology

    Philosophy of Biology: The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    Theory can help address cell and molecular biology’s major challenges, particularly those arising from large omics datasets.
    1. Genetics and Genomics

    Environmental Learning: How experience shapes individuality

    Bassem A Hassan
    Behavioural diversity across fruit flies changes with individual learning, even when genetic, past and momentary environmental factors are held constant.
    Version of Record
    Insight