Magazine

Highlighting the latest research and giving a voice to scientists
Illustration by Davide Bonazzi

Latest articles

    1. Stem Cells and Regenerative Medicine

    Hematopoiesis: Counting blood precursors

    Sarah Duchamp de Chastaigne, Catherine M Sawai
    A new mathematical model can estimate the number of precursor cells that contribute to regenerating blood cells in mice.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Neuroscience

    Spatial Attention: Time to get deep

    Max Schulz, Malte Wöstmann
    Asymmetries in the size of structures deep below the cortex explain how alpha oscillations in the brain respond to shifts in attention.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Neuroscience

    Neural Plasticity: Restoring cerebellar-dependent learning

    Jessica L Verpeut
    Behavioral and pharmaceutical interventions reverse defects associated with increased cerebellar long-term depression in a mouse model of Fragile X syndrome.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics
    3. Cell Biology
    Plasma membrane going around a banner with two different kinases and one affecting the nucleus/cell cycle. Phosphates are dotted in the background

    Special Issue: Allosteric Regulation of Kinase Activity

    Edited by Volker Dötsch et al.
    Our latest Special Issue brings together research on the allosteric regulation of kinase activity.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Special Issue: Allosteric regulation of kinase activity

    Amy H Andreotti, Volker Dötsch
    The articles in this special issue highlight how modern cellular, biochemical, biophysical and computational techniques are allowing deeper and more detailed studies of allosteric kinase regulation.
    Editorial
    Formats available:
    • HTML
    • PDF
    1. Neuroscience

    Decision Making: Unraveling the enigmatic role of the subthalamic nucleus

    Qianli Yang
    Subpopulations of neurons in the subthalamic nucleus have distinct activity patterns that relate to the three hypotheses of the Drift Diffusion Model.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Neuroscience

    Connectomes: Mapping the fly nerve cord

    Anna Seggewisse, Michael Winding
    The first neuronal wiring diagram of an insect nerve cord, which includes biological information on cell type and organisation, enables further investigation into premotor circuit function.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Chromosomes and Gene Expression

    Tardigrades: Surviving extreme radiation

    Chaitra Shree Udugere Shivakumara Swamy, Thomas C Boothby
    Tiny animals known as tardigrades use a combination of DNA repair machinery and a novel protein to mend their genome after intense ionizing radiation.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Cell Biology
    2. Physics of Living Systems

    Cell Migration: Pump up the volume

    Qin Ni, Sean X Sun
    An influx of water molecules can help immune cells called neutrophils to move to where they are needed in the body.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Viral Variants: How mutations affect function

    Thomas Kuhlman
    A new study reveals how naturally occurring mutations affect the biophysical properties of nucleocapsid proteins in SARS-CoV-2.
    Insight
    Formats available:
    • HTML
    • PDF