Magazine

Highlighting the latest research and giving a voice to scientists
Illustration by Davide Bonazzi

Highlights

    1. Microbiology and Infectious Disease

    A back-up mechanism for replication

    Godefroid Charbon, Anders Løbner-Olesen
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Receptors versus viruses

    Ping-Ping Liu, Zhe Wei, Xian-Wei Wang
    1. Genetics and Genomics
    2. Neuroscience

    Responding to pain

    Jean-Christophe Boivin, Tomoko Ohyama

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Latest articles

    1. Immunology and Inflammation

    Interferon Signaling: Immobilizing bacteria to prevent infections

    Patricia Reist Iscar, Petr Broz
    The interferon-induced GTPase GVIN1 prevents bacteria from spreading among cells by coating them and rendering them immobile.
    Version of Record
    Insight
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Cell Surface Receptors: Virus attacks fish by muscling its way into cells

    Ping-Ping Liu, Zhe Wei, Xian-Wei Wang
    Nervous necrosis virus typically enters host cells via endocytosis, but it can also enter via a process called macropinocytosis.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Helicase Loading: A back-up mechanism for replication

    Godefroid Charbon, Anders Løbner-Olesen
    A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.
    Version of Record
    Insight
    1. Neuroscience

    Consciousness: Did you see it?

    Ling Liu
    Cautious reporting choices can artificially enhance how well analyses of brain activity reflect conscious and unconscious experiences, making distinguishing between the two more challenging.
    Version of Record
    Insight
    1. Cell Biology
    2. Neuroscience

    Vision: A pathway to sight

    Katherine J Wert
    The breakdown of glutamine is an important metabolic pathway for the health and survival of rod photoreceptors within the retina.
    Version of Record
    Insight
    1. Neuroscience

    Synaptic Plasticity: A new mode of action for unconventional NMDA receptors

    Ikuko Smith
    Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.
    Version of Record
    Insight
    1. Genetics and Genomics
    2. Neuroscience

    Pain: Epidermal cells and sensory neurons team up

    Jean-Christophe Boivin, Tomoko Ohyama
    Experiments in fruit fly larvae show that epidermal cells can communicate with sensory neurons to drive responses to pain.
    Version of Record
    Insight
    1. Chromosomes and Gene Expression

    Gene Regulation: Linking O-GlcNAc and intron retention

    John A Hanover
    An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    Cell Signaling: Not all dimers are equal

    Jeet H Patel, Mary C Mullins
    Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.
    Version of Record
    Insight
    1. Immunology and Inflammation

    Bacterial Clearance: With a little help from T cells

    Troy Burtchett, Neal Hammer
    Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.
    Version of Record
    Insight