Magazine

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Cell Signaling: Uncovering the secret life of Rho GTPases

   Jenna A Perry, Amy Shaub Maddox

   New methods to directly visualize Rho GTPases reveal how a protein called RhoGDI regulates the activity of these 'molecular switches' at the plasma membrane.
2. 1. Human Biology and Medicine
   2. Immunology and Inflammation

   Sepsis: Modelling survival

   Teresa A Zimmers, Leonidas G Koniaris

   A new mouse model of sepsis can reproduce the long-term muscle weakness seen in patients who survive this life-threatening illness.
3. 1. Computational and Systems Biology

   Meta-Research: Releasing a preprint is associated with more attention and citations for the peer-reviewed article

   Darwin Y Fu, Jacob J Hughey
4. 1. Neuroscience

   Neurodegeneration: Fly model sheds light on brain disease

   Martin H Berryer et al.

   Experiments on flies suggest that a gain-of-function mechanism in a protein called CSPɑ contributes to the progressive brain disease CLN4.
5. 1. Genetics and Genomics

   Genetic Variation: Searching for solutions to the missing heritability problem

   Luisa F Pallares

   Rare genetic variants in yeast explain a large amount of phenotypic variation in a complex trait like growth.
6. 1. Developmental Biology
   2. Microbiology and Infectious Disease

   Plant Disease: Cycling in synchrony

   Míriam Osés-Ruiz, Nicholas J Talbot

   The corn smut fungus uses two different mechanisms to control its cell cycle when it is infecting plants.
7. 1. Immunology and Inflammation
   2. Neuroscience

   Autoimmunity: Bringing on the itch

   Daniel A Waizman et al.

   Neutrophils are the first immune cells that enter the skin and cause itch in atopic dermatitis.
8. 1. Cancer Biology

   Philosophy of Biology: Characterizing causality in cancer

   Elena Rondeau et al.

   Ideas about causality from philosophy can help scientists to better understand how cancerous tumors grow and spread in the body.
9. 1. Cell Biology
   2. Evolutionary Biology

   Multicellularity: How contraction has shaped evolution

   Mukund Thattai

   Two new unicellular organisms reveal that coordinated contractions of groups of cells using actomyosin predated animal multicellularity during evolution.
10. 1. Neuroscience

    Behavior: The cerebellum shows its stripes

    Ashley L Holloway, Talia N Lerner

    New studies examine how the different sub-structures in the cerebellum are organized to receive information during complex behavioral tasks.