Magazine

Highlighting the latest research and giving a voice to scientists
Illustration by Davide Bonazzi

Highlights

    1. Computational and Systems Biology
    2. Neuroscience

    Circadian rhythms

    Gabriele Andreatta, Charles N Allen
    1. Medicine
    2. Neuroscience

    Multi-analyst studies

    Balazs Aczel et al.
    1. Neuroscience

    Pain: Why sex matters

    Josette J Wlaschin et al.

Highlights controls:

Latest articles

    1. Cancer Biology

    Science Forum: Is preclinical research in cancer biology reproducible enough?

    Patrick Bodilly Kane, Jonathan Kimmelman
    Results from the Reproducibility Project: Cancer Biology provide a picture of the rate of false positives in cancer preclinical research, but it is still not clear if research in this field is less reproducible than it should be.
    1. Cancer Biology

    Reproducibility in Cancer Biology: What have we learned?

    Peter Rodgers, Andy Collings
    As the final outputs of the Reproducibility Project: Cancer Biology are published, it is clear that preclinical research in cancer biology is not as reproducible as it should be.
    Editorial
    Available as:
    • HTML
    • PDF
    1. Cancer Biology

    Reproducibility in Cancer Biology: Challenges for assessing replicability in preclinical cancer biology

    Timothy M Errington et al.
    A project to repeat experiments from high-impact papers in cancer biology encountered a series of challenges, many of which were caused by a lack of detail in the original papers.
    1. Structural Biology and Molecular Biophysics

    Cell Signaling: The many states of STIM1

    Marc Fahrner, Christoph Romanin
    Harnessing single-molecule FRET illuminates the structural changes necessary for a protein to fine-tune the influx of calcium when reserves inside a cell run low.
    Insight
    Available as:
    • HTML
    • PDF
    1. Neuroscience

    Magnetic Resonance: Mapping the visual world to the human brain

    Betina Ip, Holly Bridge
    The visual maps measured non-invasively in the brain of human and non-human primates reliably reflect the underlying neuronal responses recorded with invasive electrodes.
    Insight
    Available as:
    • HTML
    • PDF
    1. Neuroscience

    Pain: Why sex matters

    Josette J Wlaschin et al.
    The immune mechanisms underlying hypersensitivity to pain after nerve injury are different in male and female mice.
    Insight
    Available as:
    • HTML
    • PDF
    1. Computational and Systems Biology
    2. Neuroscience

    Circadian Rhythm: How neurons adjust to diurnality

    Gabriele Andreatta, Charles N Allen
    Being active during the day requires a slow-closing ion channel that dampens the activity of neurons in a specific area of the brain.
    Insight
    Available as:
    • HTML
    • PDF
    1. Medicine
    2. Neuroscience

    Science Forum: Consensus-based guidance for conducting and reporting multi-analyst studies

    Balazs Aczel et al.
    Using multiple analysts to independently analyze the same dataset has the potential to explore and strengthen the robustness of results and conclusions in basic and applied research.
    1. Cell Biology
    2. Medicine

    Funding: Blinding peer review

    Michael A Taffe
    Concealing the identity of the principal investigator only partially closes the success gap between white and African American or Black researchers in NIH grant applications.
    Insight
    Available as:
    • HTML
    • PDF