Magazine

Highlighting the latest research and giving a voice to scientists
Illustration by Davide Bonazzi

Highlights

    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Targeting cardiac repair

    Stanislao Igor Travisano, Ching-Ling Lien
    1. Cell Biology

    Returning aging cells to productivity

    Rachana S Vaidya, Simon Y Tang
    1. Immunology and Inflammation

    The double-edged nature of trained immunity

    Chrissy M Leopold Wager, Larry S Schlesinger
    1. Biochemistry and Chemical Biology

    Searching for druggable targets

    Lana Heganovic, Luiz FM Passalacqua
    1. Computational and Systems Biology

    Methylation and mRNA metabolism

    Sarah Hallstein, Julian König

Highlights controls:

Latest articles

    1. Plant Biology

    Symbiosis: How plants pick their friends

    Estelle Grundy, Michael Udvardi
    A protein called RIN4 has a central role in helping legumes such as soybean and the bacteria rhizobia to develop a mutually beneficial relationship.
    Version of Record
    Insight
    1. Evolutionary Biology

    Evolutionary Biology: Embracing the complexity of cooperation

    Benjamin Allen
    A theoretical framework for analyzing the evolution of nonlinear cooperative interactions is taking shape.
    Version of Record
    Insight
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cardiac Repair: Aiming for spatial and temporal control of gene expression

    Stanislao Igor Travisano, Ching-Ling Lien
    Bioluminescent imaging is helping researchers better understand the effectiveness of tissue regeneration enhancers delivered to injured heart tissue by different adeno-associated virus vectors.
    Version of Record
    Insight
    1. Cell Biology

    Senescence: Returning aging cells to productivity

    Rachana S Vaidya, Simon Y Tang
    Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.
    Version of Record
    Insight
    1. Immunology and Inflammation

    Acute Lung Injury: The double-edged nature of trained immunity

    Chrissy M Leopold Wager, Larry S Schlesinger
    Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.
    Version of Record
    Insight
    1. Biochemistry and Chemical Biology

    RNA: Searching for druggable targets

    Lana Heganovic, Luiz FM Passalacqua
    A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.
    Version of Record
    Insight
    1. Computational and Systems Biology

    Methylation: Modifying gene expression through passive forces

    Sarah Hallstein, Julian König
    The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
    Version of Record
    Insight
  1. Episode 99: June 2025

    In this episode, we hear about giant viruses, monkeys who wash their food, sepsis in infant pigs, how cancers can cause extra tentacles to grow in hydra, and the impact of speaking multiple languages on the structure of the cortex.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Cancer: Reading the DNA of telomeres

    Shamayita Roy, Claus M Azzalin
    Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.
    Version of Record
    Insight
    1. Medicine

    Aging: Multiple roles for a mitochondrial enzyme

    Xicong Tang, Hongyu Qiu
    The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.
    Version of Record
    Insight